Cedrenylacetat | 312964-97-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: Cedrenylacetat
• 英文别名: acetic acid-(3,6,8,8-tetramethyl-octahydro-3a,7-methano-azulen-6-yl ester)；Essigsaeure-(3,6,8,8-tetramethyl-octahydro-3a,7-methano-azulen-6-ylester)；cedryl acetate；(2,6,6,8-tetramethyl-8-tricyclo[5.3.1.01,5]undecanyl) acetate
• CAS: 312964-97-9
• 化学式: C₁₇H₂₈O₂
• 分子量: 264.408
• InChiKey: HQKQRXZEXPXXIG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  19
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  乙酸酐 、 alkaline earth salt of/the/ methylsulfuric acid 生成 Cedrenylacetat
  参考文献：
  名称：

  A multivariate analysis of the association between social class of origin and current social class with self-rated general health and psychological health among 16-year-old Australians

  摘要：

  Abstract: Background: A recent review of international literature concludes that there is a relative absence of social class differentials in health in early youth. There is an absence of Australian studies on the effect of social class on the health of this age group. Aims: To examine the association between social class and health among 16‐year‐old Australians. Methods: The data on 1048 16‐year‐olds came from the fifth wave (1993) of the Australian Youth Survey conducted by the former Department of Employment, Education and Training. Outcome measures were self‐rated general health and psychological health (GHQ‐12). Binary logistic regression was used to analyse data. Results: Neither social class of origin nor current social class was associated with self‐rated general health or psychological health. Conclusion: The argument that social class inequalities in health exist in childhood, disappear during early youth, and reappear later appears to hold ground within the Australian context.

  DOI：

  10.1111/j.1445-5994.2000.tb04359.x

文献信息

• [EN] PERFUME SYSTEM FOR PERFUMED CONSUMER PRODUCT<br/>[FR] SYSTÈME DE PARFUM POUR PRODUIT PARFUMÉ DE CONSOMMATION
  申请人：FIRMENICH & CIE

  公开号：WO2021214205A1

  公开（公告）日：2021-10-28

  The present invention relates to a perfume system comprising a core-shell microcapsule A, optionally, a core-shell microcapsule B, and optionally, a free perfume oil, wherein the core of the core-shell microcapsule A and/or the free perfume oil comprises a 2-oxoacetate derivative of formula (I) as well as a perfumed consumer product comprising the same and methods and uses of the same for enhancing, conferring, increasing and/or modifying the fragrance properties and/or the fragrance intensity of perfumed consumer products.

  本发明涉及一种香水系统，包括一个核-壳微胶囊A，可选地，一个核-壳微胶囊B，以及可选地，一个游离香水油，其中核-壳微胶囊A的核和/或游离香水油包含式(I)的2-氧代乙酸酯衍生物，以及包含相同的香水消费产品以及用于增强、赋予、增加和/或修改香水消费产品的香气特性和/或香气强度的方法和用途。
• ORGANIC COMPOUNDS
  申请人：Givaudan SA

  公开号：US20200330346A1

  公开（公告）日：2020-10-22

  The present invention refers to indanone derivatives of formula (I) wherein R 1 is selected from hydrogen, methyl and ethyl; R 2 is selected from hydrogen, methyl and ethyl, and R 3 is selected from hydrogen and methyl; or R 2 and R 3 form together with the carbon atoms to which they are attached C 3 -C 5 cycloalkyl; and R 4 is selected from C 2 -C 5 alkyl, C 2 -C 5 alkenyl, C 1 -C 4 alkoxy, C 3 -C 5 cycloalkyl, and C 3 -C 6 cycloalkenyl. The invention further refers to perfume compositions and fragrance applications comprising them.

  本发明涉及式(I)的吲哚酮衍生物，其中R1选择氢、甲基和乙基；R2选择氢、甲基和乙基，R3选择氢和甲基；或R2和R3与它们附着的碳原子一起形成C3-C5环烷基；R4选择C2-C5烷基、C2-C5烯基、C1-C4烷氧基、C3-C5环烷基和C3-C6环烯基。该发明还涉及包含它们的香水组合物和香料应用。
• COMPOSITION FOR PREVENTING OR AMELIORATING HYPERSENSITIVE SKIN COMPRISING CEDROL OR DERIVATIVES THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF
  申请人：University Of Seoul Industry Cooperation Foundation

  公开号：EP3384905A1

  公开（公告）日：2018-10-10

  The present invention relates to a pharmaceutical composition for use in preventing or treating autoimmune diseases comprising cedrol or a pharmaceutically acceptable salt thereof as an active ingredient. Particularly, the cedrol or the derivative thereof of the present invention inhibits the expression of IL-17A, and in particular, cedrol, cedryl acetate, and cedrene exhibit the effect of delaying the outbreak of psoriasis and treating thereof in a psoriasis animal model. Therefore, these compounds can be used for the treatment of autoimmune diseases mediated by IL-17.

  本发明涉及一种用于预防或治疗自身免疫性疾病的药物组合物，其活性成分包括西地孕酮或其药学上可接受的盐。特别是，本发明的西地孕酮或其衍生物可抑制 IL-17A 的表达，尤其是西地孕酮、醋酸西地孕酮和西地仑在牛皮癣动物模型中表现出延缓牛皮癣爆发和治疗牛皮癣的效果。因此，这些化合物可用于治疗由 IL-17 介导的自身免疫性疾病。
• FRAGRANCE COMPOSITIONS
  申请人：Givaudan SA

  公开号：EP3403641A1

  公开（公告）日：2018-11-21

  Disclosed are fragrance compositions comprising ethyl cyclohexanoate.

  公开了包含环己酸乙酯的香料组合物。
• (2S,4R)-4-METHYL-2-(2-METHYLBUT-1-EN-1-YL)TETRAHYDRO-2H-PYRANEN AS FRAGRANCE INGREDIENT
  申请人：Givaudan SA

  公开号：EP3666763A1

  公开（公告）日：2020-06-17

  The present invention is concerned with fragrance ingredients and with fragrance preparations, for imparting desirable odor notes to consumer products, in particular it is concerned with (2S,4R)-4-methyl-2-((Z)-2-methylbut-1-en-1-yl)tetrahydro-2H-pyran that can be used as replacements for 4-methyl-2-(2-methylprop-1-en-1-yl)tetrahydro-2H-pyran.

  本发明涉及香料成分和香料制剂，用于为消费品赋予理想的气味，特别是(2S,4R)-4-甲基-2-((Z)-2-甲基丁-1-烯-1-基)四氢-2H-吡喃，可用于替代 4-甲基-2-(2-甲基丙-1-烯-1-基)四氢-2H-吡喃。