Anemosapogenin

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: Anemosapogenin
• 英文别名: 9-hydroxy-8-(hydroxymethyl)-5a,5b,8,11a-tetramethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid
• 化学式: C₃₀H₄₈O₄
• 分子量: 472.7
• InChiKey: HXWLKAXCQLXHML-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.5
• 重原子数：
  34
• 可旋转键数：
  3
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  77.8
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• 23-HYDROXY-BETULINIC ACID DERIVATIVES, PREPARATION METHODS AND USES THEREOF
  申请人：Zhang Nan

  公开号：US20120302530A1

  公开（公告）日：2012-11-29

  The present invention discloses 23-hydroxyl-betulinic acid derivatives, including 3-oxo-23-hydroxyl-betulinic acid, 3-oxo-23-hydroxyl-dihydrobetulinic acid, and 23-hydroxyl-dihydrobetulinic acid. The present invention also discloses the preparation methods thereof and medical applications as anti-tumor and anti-HIV agents.
• [EN] TRITERPENOIDS THAT DECREASE LIPID PRODUCTION IN SEBOCYTES<br/>[FR] TRITERPÉNOÏDES DIMINUANT LA PRODUCTION DE LIPIDES DANS DES SÉBOCYTES
  申请人：AGENCY SCIENCE TECH & RES

  公开号：WO2020263188A1

  公开（公告）日：2020-12-30

  The present invention relates to methods for decreasing lipid production in sebocytes comprising the contacting of sebocytes with at least one triterpenoid compound, to compositions comprising at least one triterpenoid compound, to the use of such a composition for decreasing lipid production in sebocytes or for the manufacture of a pharmaceutical for decreasing lipid production in sebocytes, and to a cosmetic method for decreasing lipid production in sebocytes. In some embodiments, the triterpenoid compound of the herein described method is selected from the group consisting of hederagenin, ursonic acid, cycloastragenol, beta-elemonic acid, acetylursolic acid, alisol B 23-acetate, toosendanin, (20R)-protopanaxdiol, anemosapogenin, rutundic acid, and oleanolic acid.