中文名称 | 英文名称 | CAS号 | 化学式 | 分子量 |
---|---|---|---|---|
2-(2-氧代-3-吲哚)乙腈 | 2-(2-oxoindolin-3-yl)acetonitrile | 54744-66-0 | C10H8N2O | 172.186 |
—— | ethyl 2-oxo-4'H-spiro[indoline-3,5'-isoxazole]-3'-carboxylate | 1280219-26-2 | C13H12N2O4 | 260.249 |
中文名称 | 英文名称 | CAS号 | 化学式 | 分子量 |
---|---|---|---|---|
—— | (S)-2-(3-hydroxy-2-oxoindolin-3-yl)acetonitrile | 137761-24-1 | C10H8N2O2 | 188.186 |
—— | 2-(3-hydroxy-1-methyl-2-oxoindolin-3-yl)acetonitrile | 885117-65-7 | C11H10N2O2 | 202.213 |
—— | [3-hydroxy-1-(3-methyl-2-buten-1-yl)-2-oxo-2,3-dihydroindol-3-yl]acetonitrile | 885117-72-6 | C15H16N2O2 | 256.304 |
—— | 2-(1-benzyl-3-hydroxy-2-oxoindolin-3-yl)acetonitrile | —— | C17H14N2O2 | 278.31 |
—— | tert-butyl (2-(3-methoxy-1-methyl-2-oxoindolin-3-yl)ethyl)carbamate | 1280219-54-6 | C17H24N2O4 | 320.389 |
—— | 1-methyl-2,3,8,8a-tetrahydropyrrolo[2,3-b]indol-3a(1H)-ol | 101053-34-3 | C11H14N2O | 190.245 |
—— | (+/-)-8-methyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-3a-ol | —— | C11H14N2O | 190.245 |
Cesium fluoride catalyzed direct cyanomethylation of various isatins by using trimethylsilyl acetonitrile (TMSAN) as a nucleophile has been developed. The reaction has been explored for a number of isatins, with various substitutions on its aromatic ring. Further, the versatility of the reaction is demonstrated by converting the direct aldol adducts to various corresponding intermediates.