Luteolin 4'-glucoside | 6920-38-3

• 物质功能分类: 生物化工 - 提取物
• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: Luteolin 4'-glucoside
• 英文别名: 5,7-dihydroxy-2-[3-hydroxy-4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]chromen-4-one
• CAS: 6920-38-3
• 化学式: C₂₁H₂₀O₁₁
• 分子量: 448.4
• InChiKey: UHNXUSWGOJMEFO-UHFFFAOYSA-N

物化性质

• 熔点：
  210°C (dec.)
• 沸点：
  814.5±65.0 °C(Predicted)
• 密度：
  1.713±0.06 g/cm3(Predicted)
• 物理描述：
  Solid

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  32
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  186
• 氢给体数：
  7
• 氢受体数：
  11

安全信息

• 储存条件：
  存储条件：2-8℃，请保持干燥并密封。

制备方法与用途

木犀草素-4'-O-葡萄糖苷是一种IL-5抑制剂，其IC50值为3.7μM。这种化合物不仅对抗高尿酸血症和急性痛风性关节炎有效，还表现出抗癌活性[1][2][3]。

文献信息

• Extract of the aerial parts of Lawsonia inermis and its preparation method
  申请人：PIERRE FABRE DERMO-COSMETIQUE

  公开号：US11207265B2

  公开（公告）日：2021-12-28

  The invention relates to an extract of the aerial parts of Lawsonia inermis, as well as its preparation method and the extract that can be obtained by said method. The invention also relates to a cosmetic dye composition comprising such an extract. The invention finally concerns a cosmetic method for dying keratin fibers comprising the application of such a composition.

  本发明涉及光亮鼠李(Lawsonia inermis)地上部分的一种提取物，及其制备方法以及通过所述方法能够获得的提取物。本发明还涉及一种含有这种提取物的化妆品染料组合物。最后，本发明涉及一种用于使角蛋白纤维染色的化妆品方法，其包括应用这种组合物。
• EXTRACT OF THE AERIAL PARTS OF LAWSONIA INERMIS AND ITS PREPARATION METHOD
  申请人：PIERRE FABRE DERMO-COSMETIQUE

  公开号：US20200330365A1

  公开（公告）日：2020-10-22

  The invention relates to an extract of the aerial parts of Lawsonia inermis , as well as its preparation method and the extract that can be obtained by said method. The invention also relates to a cosmetic dye composition comprising such an extract. The invention finally concerns a cosmetic method for dying keratin fibers comprising the application of such a composition.
• PROCESS FOR PREPARING A LAWSONIA INERMIS EXTRACT
  申请人：PIERRE FABRE DERMO-COSMETIQUE

  公开号：US20220204776A1

  公开（公告）日：2022-06-30

  The present disclosure relates to a process for preparing a Lawsonia inermis extract which is rich in Lawsone. It also relates to the extract which may be obtained by said process and to a composition comprising thereof. The disclosure also relates to a method for dying fibers, in particular keratin fibers.
• [EN] EXTRACT OF THE AERIAL PARTS OF LAWSONIA INERMIS AND ITS PREPARATION METHOD<br/>[FR] EXTRAIT DES PARTIES AÉRIENNES DE LAWSONIA INERMIS ET SON PROCÉDÉ DE PRÉPARATION
  申请人：FABRE PIERRE DERMO COSMETIQUE

  公开号：WO2019115651A1

  公开（公告）日：2019-06-20

  The invention relates to an extract of the aerial parts of Lawsonia inermis, as well as its preparation method and the extract that can be obtained by said method. The invention also relates to a cosmetic dye composition comprising such an extract. The invention finally concerns a cosmetic method for dying keratin fibers comprising the application of such a composition.
• [EN] PROCESS FOR PREPARING A LAWSONIA INERMIS EXTRACT<br/>[FR] PROCÉDÉ DE PRÉPARATION D'UN EXTRAIT DE LAWSONIA INERMIS
  申请人：FABRE PIERRE DERMO COSMETIQUE

  公开号：WO2020249746A1

  公开（公告）日：2020-12-17

  The present disclosure relates to a process for preparing a Lawsonia inermis extract which is rich in Lawsone. It also relates to the extract which may be obtained by said process and to a composition comprising thereof. The disclosure also relates to a method for dying fibers, in particular keratin fibers.