1-methyl,7,7-dimethyl,bicyclo<2.2.1>heptane,2-carboxylic acid | 62280-85-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 1-methyl,7,7-dimethyl,bicyclo<2.2.1>heptane,2-carboxylic acid
• 英文别名: 1,7,7-trimethyl-norbornane-2ξ-carboxylic acid；1,7,7-trimethyl-norbornane-2-carboxylic acid；1,7,7-Trimethyl-norbornan-2-carbonsaeure；1.7.7-Trimethyl-bicyclo-[1.2.2]-heptan-carbonsaeure-(2)；Camphancarbonsaeure-(2)；2-Bornanecarboxylic acid；1,7,7-trimethylbicyclo[2.2.1]heptane-2-carboxylic acid
• CAS: 62280-85-7
• 化学式: C₁₁H₁₈O₂
• mdl: MFCD20542794
• 分子量: 182.263
• InChiKey: ZURRKVIQUKNLHF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  13
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.909
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1-methyl,7,7-dimethyl,bicyclo<2.2.1>heptane,2-carboxylic acid 在 manganese borate 、 臭氧 作用下， 生成 白樟油
  参考文献：
  名称：

  Ikeda, Scientific Papers of the Institute of Physical and Chemical Research (Japan), vol. 7, p. 10

  摘要：

  DOI：
• 作为产物：
  描述：

  1-bornyl-ethanone 在 sodium hypobromide 作用下， 生成 1-methyl,7,7-dimethyl,bicyclo<2.2.1>heptane,2-carboxylic acid
  参考文献：
  名称：

  Rupe; Hirschmann, Helvetica Chimica Acta, 1928, vol. 11, p. 1195

  摘要：

  DOI：

文献信息

• Serotonin transport inhibitors
  申请人：——

  公开号：US20030105096A1

  公开（公告）日：2003-06-05

  The present invention relates to the therapeutic use of non-amine tropane analogues that bind to the SERT to treat neuropsychiatric disorders.

  本发明涉及治疗非胺类曲梯巴酮类似物与SERT结合以治疗神经精神障碍的用途。
• [EN] 5-METHOXY. 3'-OH UNBLOCKED, FAST PHOTOCLEAVABLE TERMINATING NUCLEOTIDES AND METHODS FOR NUCLEIC ACID SEQUENCING<br/>[FR] 5-MÉTHOXY-NUCLÉOTIDES À TERMINAISON RAPIDEMENT PHOTOCLIVABLE NON BLOQUÉS EN 3'OH ET PROCÉDÉS DE SÉQUENÇAGE D'ACIDE NUCLÉIQUE
  申请人：LASERGEN INC

  公开号：WO2013040257A1

  公开（公告）日：2013-03-21

  The present invention relates generally to 3'-OH unblocked nucleotides and nucleosides labeled and unlabeled with 5-methoxy-substituted nitrobenzyl-based photocleavable terminating groups for use in methods and systems related to DNA and RNA sequencing and analysis. These compounds may be used as reversible terminators as they exhibit fast nucleotide incorporation kinetics, single-base termination, high nucleotide selectivity, and rapid terminating group cleavage that results in a naturally occurring nucleotide.

  本发明通常涉及用于DNA和RNA测序和分析方法及系统中的3'-OH未阻断核苷酸和核苷的标记和未标记的5-甲氧基取代硝基苯基光致裂解终止基团。这些化合物可用作可逆终止剂，因为它们表现出快速的核苷酸结合动力学、单碱基终止、高核苷酸选择性和快速的终止基团裂解，导致自然发生的核苷酸。
• Chemical amplification type resist composition
  申请人：Yamada Airi

  公开号：US20080269506A1

  公开（公告）日：2008-10-30

  The present invention provides a sulfonium salt of the formula (Ia) a polymeric compound comprising a structural unit of the formula (Ib) and a chemical amplification type positive resist composition comprising (A) an acid generator comprising at least one compound selected from the group consisting of a sulfonium salt of the formula (Ia), a polymeric compound comprising a structural unit of the formula (Ib), and a sulfonium salt of the formula (Ic); and (B) resin which contains a structural unit having an acid labile group and which itself is insoluble or poorly soluble in an alkali aqueous solution but becomes soluble in an alkali aqueous solution by the action of an acid.

  本发明提供了一种公式(Ia)的硫鎓盐，包括一个结构单元的聚合物化合物的公式(Ib)，以及一种化学放大型正性光刻胶组合物，包括(A)至少选择自硫鎓盐的公式(Ia)、一个结构单元的聚合物化合物的公式(Ib)和硫鎓盐的公式(Ic)组成的酸发生剂；以及(B)含有酸敏感基团的结构单元的树脂，本身在碱性水溶液中不溶或难溶，但在酸的作用下变得可溶于碱性水溶液。
• [EN] CYCLOPROPANATION PROCESS<br/>[FR] PROCÉDÉ DE CYCLOPROPANATION
  申请人：GIVAUDAN SA

  公开号：WO2009023980A1

  公开（公告）日：2009-02-26

  A method for the preparation of cyclopropyl carbinols by cyclopropanation of unsaturated alcoholates, utilising a reagent system selected from (A) magnesium metal and dibromomethane, and (B) dibromomethane and a tertiary Grignard reagent, the reaction being carried out in the presence of an ether solvent. The process is useful, for example, for the preparation of ingredients for the flavour and fragrance industry.

  一种通过使用选自(A)镁金属和二溴甲烷，以及(B)二溴甲烷和三级格氏试剂的试剂体系，通过环丙烷化不饱和醇酸盐来制备环丙基醇的方法，该反应在醚溶剂存在下进行。该过程可用于为香料和香精行业的成分制备。
• PROCESS FOR PREPARING POLYMERS
  申请人：IMPERIAL INNOVATIONS LIMITED

  公开号：US20170313818A1

  公开（公告）日：2017-11-02

  A process for preparing non-naturally-occurring defined monomer sequence polymers is provided, and in which a high degree of synthetic control is obtained by the use of solvent resistant diafiltration membranes. Also provided is a process for separating non-naturally-occurring defined monomer sequence polymers from synthetic by-products or excess reagents using solvent resistant diafiltration membranes, and a use of a solvent resistant diafiltration membrane in processes for preparing and separating non-naturally-occurring defined monomer sequence polymers.

  提供了一种制备非自然存在的定义单体序列聚合物的方法，通过使用耐溶剂透析膜获得高度的合成控制。还提供了一种利用耐溶剂透析膜从合成副产物或过剩试剂中分离非自然存在的定义单体序列聚合物的方法，以及在制备和分离非自然存在的定义单体序列聚合物的过程中使用耐溶剂透析膜的用途。