3,4-dihydroxyphenethyl alcohol 4-O-β-D-glucopyranoside | 54695-80-6

• 物质功能分类: 分析化学 - 标准品 - 药典标准品和杂质标准品
• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3,4-dihydroxyphenethyl alcohol 4-O-β-D-glucopyranoside
• 英文别名: 2-(3-hydroxy-4-O-D-β-glucopyranosylphenyl)ethanol；hydroxytyrosol 4-O-glucoside；hydroxytyrosol 4-glucoside；hydroxytyrosol glucoside；(2S,3R,4S,5S,6R)-2-[2-hydroxy-4-(2-hydroxyethyl)phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
• CAS: 54695-80-6
• 化学式: C₁₄H₂₀O₈
• 分子量: 316.308
• InChiKey: JVOQYXVFJHETKK-RKQHYHRCSA-N

物化性质

• 沸点：
  613.5±55.0 °C(Predicted)
• 密度：
  1.540±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -1.3
• 重原子数：
  22
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  140
• 氢给体数：
  6
• 氢受体数：
  8

安全信息

• 储存条件：
  2-8℃

反应信息

• 作为反应物：
  描述：

  3,4-dihydroxyphenethyl alcohol 4-O-β-D-glucopyranoside 在 盐酸 、 水 作用下， 以 甲醇 为溶剂， 反应 3.0h， 生成 a-无水葡萄糖酯
  参考文献：
  名称：

  Terpenoids and phenethyl glucosides from Hyssopus cuspidatus (Labiatae)

  摘要：

  Monoterpenoids (3 and 4), sesquiterpenoid (2), diterpenoid (1) and four phenethyl glucosides (5-8), together with fourteen known compounds, were isolated from the whole herb of Hyssopus cuspidatus. Their structures were determined by spectroscopic means. The abietane-type diterpenoids (1, 9, 10), rosmarinic acid (15) and salvigenin (17) inhibited leukotriene (LT) C-4 secretion from primary alveolar cells of Wistar rats. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.phytochem.2011.07.008
• 作为产物：
  描述：

  2-hydroxy-4-(2-hydroxyethyl)phenyl 6-(4-hydroxy-3,5-dimethoxybenzoate) O-β-D-glucopyranoside 在 sodium methylate 作用下， 以 甲醇 为溶剂， 生成 3,4-dihydroxyphenethyl alcohol 4-O-β-D-glucopyranoside
  参考文献：
  名称：

  Terpenoids and phenethyl glucosides from Hyssopus cuspidatus (Labiatae)

  摘要：

  Monoterpenoids (3 and 4), sesquiterpenoid (2), diterpenoid (1) and four phenethyl glucosides (5-8), together with fourteen known compounds, were isolated from the whole herb of Hyssopus cuspidatus. Their structures were determined by spectroscopic means. The abietane-type diterpenoids (1, 9, 10), rosmarinic acid (15) and salvigenin (17) inhibited leukotriene (LT) C-4 secretion from primary alveolar cells of Wistar rats. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.phytochem.2011.07.008

文献信息

• Compositions for potentiating glutatthione
  申请人：Chiba Tomohiro

  公开号：US20060257351A1

  公开（公告）日：2006-11-16

  A composition for potentiating glutathione, which contains at least one member selected from the group consisting of 2-(3,4-dihydroxyphenyl)ethanol or a glycoside thereof, a plant containing 2-(3,4-dihydroxyphenyl)ethanol or a glycoside thereof, an extract of said plant, a hydrolysate of said plant, and a hydrolysate of the extract of said plant (excluding Olea europaea and an extract thereof), and which further contains at least one member selected from among an S-containing compound that is a supply source of cysteine, a protein that contains cysteine and/or cystine, a yeast that contains cysteine and/or cystine, and a vitamin.

  一种用于增强谷胱甘肽作用的组合物，包含至少从以下组合中选择的一种成员：2-(3,4-二羟基苯基)乙醇或其糖苷，含有2-(3,4-二羟基苯基)乙醇或其糖苷的植物，该植物的提取物，该植物的水解产物，以及该植物提取物的水解产物（不包括欧洲橄榄和其提取物），并且进一步包含至少从以下成员中选择的一种：供应半胱氨酸的含硫化合物，含有半胱氨酸和/或半胱氨酸的蛋白质，含有半胱氨酸和/或半胱氨酸的酵母，以及维生素。
• Ageta, Masayuki; Ishimaru, Kanji; Nonaka, Gen-Ichiro, Chemical and pharmaceutical bulletin, 1988, vol. 36, # 3, p. 870 - 876
  作者：Ageta, Masayuki、Ishimaru, Kanji、Nonaka, Gen-Ichiro、Nishioka, Itsuo

  DOI：——

  日期：——
• US7740831B2
  申请人：——

  公开号：US7740831B2

  公开（公告）日：2010-06-22
• Terpenoids and phenethyl glucosides from Hyssopus cuspidatus (Labiatae)
  作者：Megumi Furukawa、Mitsuko Makino、Emika Ohkoshi、Taketo Uchiyama、Yasuo Fujimoto

  DOI：10.1016/j.phytochem.2011.07.008

  日期：2011.12

  Monoterpenoids (3 and 4), sesquiterpenoid (2), diterpenoid (1) and four phenethyl glucosides (5-8), together with fourteen known compounds, were isolated from the whole herb of Hyssopus cuspidatus. Their structures were determined by spectroscopic means. The abietane-type diterpenoids (1, 9, 10), rosmarinic acid (15) and salvigenin (17) inhibited leukotriene (LT) C-4 secretion from primary alveolar cells of Wistar rats. (C) 2011 Elsevier Ltd. All rights reserved.