(+)-bornyl diphosphate | 64822-87-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: (+)-bornyl diphosphate
• 英文别名: phosphono [(1R,2S,4R)-1,7,7-trimethyl-2-bicyclo[2.2.1]heptanyl] hydrogen phosphate
• CAS: 64822-87-3
• 化学式: C₁₀H₂₀O₇P₂
• 分子量: 314.212
• InChiKey: VZPAJODTZAAANV-WEDXCCLWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  19
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  113
• 氢给体数：
  3
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  (+)-冰片 在 四丁基磷酸氢铵 、 三氯乙腈 作用下， 反应 0.33h， 生成 (+)-bornyl monophosphate 、 (+)-bornyl diphosphate
  参考文献：
  名称：

  Stereochemical disposition of the geminal dimethyl groups in the enzymatic cyclization of geranyl diphosphate to (+)-bornyl diphosphate by recombinant (+)-bornyl diphosphate synthase from Salvia officinalis

  摘要：

  Regiospecifically deuterated geranyl diphosphate, in concert with NMR spectrometry, was employed to demonstrate that the trans-methyl group (C8) of geranyl diphosphate becomes the C9 carbon of (+)-bornyl diphosphate (geminal methyl syn to the diphosphate moiety) and that the cis-methyl group (C9) becomes the C8 (geminal methyl anti to the diphosphate). The syntheses of the relevant substrates and products, with accompanying spectrometric data are provided. (C) 2001 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4020(01)00451-3

文献信息

• [EN] PRODUCTION OF TERPENES AND TERPENOIDS<br/>[FR] PRODUCTION DE TERPÈNES ET DE TERPÉNOÏDES
  申请人：UNIV DANMARKS TEKNISKE

  公开号：WO2019057258A1

  公开（公告）日：2019-03-28

  This invention relates to a transgenic bryophytic cell capable of producing geranyl pyrophosphate (GPP), farnesyl-pyrophosphate (FPP) and/or geranylgeranyl pyrophosphate (GGPP) comprising at least one heterologous nucleic acid molecule encoding at least one chimeric protein comprising at least a first and a second polypeptide where said first and second polypeptides are operationally linked and said first polypeptide is a lipid body-associated protein.The invention further relates to a method for producing the transgenic bryophytic cell as well as a method for preparing terpenes and terpenoids using the transgenic bryophytic cells.
• Stereochemical disposition of the geminal dimethyl groups in the enzymatic cyclization of geranyl diphosphate to (+)-bornyl diphosphate by recombinant (+)-bornyl diphosphate synthase from Salvia officinalis
  作者：Mitchell L Wise、Hyung-Jung Pyun、Greg Helms、Bryce Assink、Robert M Coates、Rodney B Croteau

  DOI：10.1016/s0040-4020(01)00451-3

  日期：2001.6

  Regiospecifically deuterated geranyl diphosphate, in concert with NMR spectrometry, was employed to demonstrate that the trans-methyl group (C8) of geranyl diphosphate becomes the C9 carbon of (+)-bornyl diphosphate (geminal methyl syn to the diphosphate moiety) and that the cis-methyl group (C9) becomes the C8 (geminal methyl anti to the diphosphate). The syntheses of the relevant substrates and products, with accompanying spectrometric data are provided. (C) 2001 Elsevier Science Ltd. All rights reserved.