menthyl bromide | 64240-80-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: menthyl bromide
• 英文别名: 3-bromo-p-menthane；3-Brom-p-menthan；3-p-menthyl bromide；Menthylbromide；2-bromo-4-methyl-1-propan-2-ylcyclohexane
• CAS: 64240-80-8
• 化学式: C₁₀H₁₉Br
• 分子量: 219.165
• InChiKey: MPVONIMKFUZRQI-UHFFFAOYSA-N

物化性质

• 沸点：
  105.5 °C(Press: 13 Torr)
• 密度：
  1.1504 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  menthyl bromide 在 magnesium 作用下， 生成 trans-1,4-menthane
  参考文献：
  名称：

  423.一些对-薄荷烷衍生物的构型

  摘要：

  DOI：

  10.1039/jr9370002003
• 作为产物：
  描述：

  薄荷脑 在 4-aminophenyl diphenylphosphinite 、 溴 作用下， 以 二氯甲烷 为溶剂， 反应 3.0h， 以80%的产率得到menthyl bromide
  参考文献：
  名称：

  4-氨基苯基二苯基次膦酸盐 (APDPP)，一种新的异质酸清除剂次膦酸盐 — 将醇、三甲基甲硅烷基和四氢吡喃基醚转化为具有卤素或 N-卤代琥珀酰亚胺的烷基卤

  摘要：

  制备了一种新的非均相次膦酸盐，即 4-氨基苯基二苯基次膦酸盐 (APDPP)，并用于在分子卤素或 N-卤代琥珀酰亚胺存在下将醇、三甲基甲硅烷基醚和四氢吡喃基醚有效转化为其相应的溴化物、碘化物和氯化物。该次膦酸盐中的氨基充当酸清除剂并去除产生的酸。简单的过滤很容易去除副产物次膦酸盐。关键词：4-氨基苯基二苯基次膦酸盐，醇，三甲基甲硅烷基醚，四氢吡喃基醚，卤代烷。

  DOI：

  10.1139/v06-120

文献信息

• BORATE-BASED BASE GENERATOR, AND BASE-REACTIVE COMPOSITION COMPRISING SUCH BASE GENERATOR
  申请人：WAKO PURE CHEMICAL INDUSTRIES, LTD.

  公开号：US20160340374A1

  公开（公告）日：2016-11-24

  An object of the present invention is to provide a compound which is capable of attaining a composition having high storage stability without reacting with a base-reactive compound, even in the case of storage for a long period of time in a mixed state with the base-reactive compound, such as an epoxy-based compound, as well as capable of generating a strong base (guanidines, biguanides, phosphazenes or phosphoniums) by irradiation of light (active energy rays) or heating; a base generator comprising the compound; and a base-reactive composition comprising the base generator and the base-reactive compound. The present invention relates to the compound represented by the general formula (A); the base generator comprising the compound; and the base-reactive composition comprising the base generator and the base-reactive compound. (wherein R 1 represents an alkyl group; an arylalkynyl group which may be substituted with a halogen atom, an alkyl group, an alkoxy group, or an alkylthio group; an alkenyl group; a 2-furylethynyl group; a 2-thiophenylethynyl group; or a 2,6-dithianyl group; R 2 to R 4 each independently represent an alkyl group; an arylalkynyl group which may be substituted with a halogen atom, an alkyl group, an alkoxy group, or an alkylthio group; the aryl group which may be substituted with a halogen atom, an alkyl group, an alkoxy group, or an alkylthio group; a furanyl group; a thienyl group; or an N-alkyl-substituted pyrrolyl group; Z + represents an ammonium cation having a guanidinium group, a biguanidium group or a phosphazenium group, or a phosphonium cation.)

  本发明的目的是提供一种化合物，能够在与碱反应性化合物混合状态长时间存储的情况下，仍能获得具有高储存稳定性的组合物，而不与碱反应性化合物发生反应，同时还能通过光照（活性能量射线）或加热产生强碱（胍胺、双胍胺、磷氮烷或磷銨）；包括该化合物的碱发生器；以及包括该碱发生器和碱反应性化合物的碱反应性组合物。本发明涉及由通式（A）表示的化合物；包括该化合物的碱发生器；以及包括该碱发生器和碱反应性化合物的碱反应性组合物。（其中R1代表烷基；可能被卤素原子、烷基、烷氧基或烷硫基取代的芳基炔基；烯基；2-呋喃基炔基；2-噻吩基炔基；或2,6-二硫基基；R2到R4各自独立地代表烷基；可能被卤素原子、烷基、烷氧基或烷硫基取代的芳基炔基；可能被卤素原子、烷基、烷氧基或烷硫基取代的芳基；呋喃基；噻吩基；或N-烷基取代的吡咯基；Z+代表具有胍胺基团、双胍胺基团或磷氮烷基团的铵阳离子，或磷銨阳离子。）
• Cleavage of carbonoxygen bonds. Dimethylboron bromide. A new reagent for ether cleavage
  作者：Yvan Guindon、Christiane Yoakim、Howard E. Morton

  DOI：10.1016/s0040-4039(00)88071-5

  日期：1983.1

  A general and efficient procedure for the cleavage of aliphatic, aromatic and cyclic ethers by the use of dimethylboron bromide is described.

  描述了通过使用二甲基溴化硼裂解脂肪族，芳香族和环状醚的通用且有效的方法。
• ACID-RESISTANT BASE AND/OR RADICAL GENERATOR, AND CURABLE RESIN COMPOSITION CONTAINING SAID BASE AND/OR RADICAL GENERATOR
  申请人：WAKO PURE CHEMICAL INDUSTRIES, LTD.

  公开号：US20190002403A1

  公开（公告）日：2019-01-03

  The present invention relates to a compound represented by the general formula (A), a base- and/or radical-generating agent comprising the compound, and so on. In the formula, four pieces of R 1 each independently represents a hydrogen atom or a fluorine atom; four pieces of R 2 each independently represent a fluorine atom or a trifluoromethyl group; R 3 , R 6 , R 7 and R 10 each independently represent a hydrogen atom or an alkyl group having 1 to 12 carbon atoms; R 4 and R 5 each independently represent a hydrogen atom or an alkyl group having 1 to 12 carbon atoms, or R 4 and R 5 are bonded to each other to represent an alkylene group having 2 to 4 carbon atoms; and R 8 and R 9 each independently represent a hydrogen atom, an alkyl group having 1 to 12 carbon atoms, or an aryl group having 6 to 14 carbon atoms and optionally having a substituent selected from the group consisting of an alkyl group having 1 to 6 carbon atoms, an alkoxy group having 1 to 6 carbon atoms, an alkylthio group having 1 to 6 carbon atoms, a dialkylamino group having 2 to 12 carbon atoms, a halogen atom, and a nitro group, or R 8 and R 9 are bonded to each other to represent an alkylene group having 2 to 4 carbon atoms; provided that two or three of the eight groups R 3 to R 10 are each a hydrogen atom, and, in a case where two of the eight groups are each a hydrogen atom, then three to six of the remaining groups are each an alkyl group having 1 to 12 carbon atoms, and, in a case where three of the eight groups are each a hydrogen atom, then four or five of the remaining groups are each an alkyl group having 1 to 12 carbon atoms.

  本发明涉及一种由通式（A）表示的化合物，包括该化合物的生成碱基和/或基团产生剂等。在该式中，四个R1分别独立表示氢原子或氟原子；四个R2分别独立表示氟原子或三氟甲基基团；R3、R6、R7和R10分别独立表示氢原子或具有1至12个碳原子的烷基基团；R4和R5分别独立表示氢原子或具有1至12个碳原子的烷基基团，或者R4和R5相互连接表示具有2至4个碳原子的亚烷基基团；R8和R9分别独立表示氢原子、具有1至12个碳原子的烷基基团或具有6至14个碳原子且可选地具有选自包括具有1至6个碳原子的烷基基团、具有1至6个碳原子的烷氧基团、具有1至6个碳原子的烷硫基团、具有2至12个碳原子的二烷基氨基团、卤素原子和硝基基团的取代基的芳基团，或者R8和R9相互连接表示具有2至4个碳原子的亚烷基基团；前提是八个基团R3至R10中的两个或三个分别是氢原子，并且在其中两个基团分别是氢原子的情况下，其余基团中的三到六个分别是具有1至12个碳原子的烷基基团，而在其中三个基团分别是氢原子的情况下，其余基团中的四个或五个分别是具有1至12个碳原子的烷基基团。
• Radical Alkylation of Heteroaromatic Bases with Polysilane Compounds
  作者：Hideo Togo、Ken Hayashi、Masataka Yokoyama

  DOI：10.1246/bcsj.67.2522

  日期：1994.9

  Alkyl halides were treated with protonated heteroaromatic bases in the presence of 1,1,1,3,3,3-hexamethyl-2,2-bis(trimethylsilyl)trisilane under photochemical conditions to give the corresponding alkylated heteroaromatic bases easily. The alkylation of protonated heteroaromatic bases with 1,1,1,3,3,3-hexamethyl-2-(trimethylsilyl)trisilane proceeded effectively under photochemical conditions or thermal conditions. The present method is the first report on the alkylation of heteroaromatic bases under non-oxidative conditions.

  在1,1,1,3,3,3-六甲基-2,2-双(三甲基甲硅烷基)三硅烷存在下，在光化学条件下用质子化杂芳族碱处理烷基卤，很容易得到相应的烷基化杂芳族碱。质子化杂芳族碱基与1,1,1,3,3,3-六甲基-2-(三甲基甲硅烷基)三硅烷的烷基化在光化学条件或热条件下有效进行。本方法是第一个关于非氧化条件下杂芳族碱基烷基化的报道。
• Tris(trimethylsilyl)silane in the Alkylation of Heteroaromatic Bases with Alkyl Halides
  作者：Hideo Togo、Ken Hayashi、Masataka Yokoyama

  DOI：10.1246/cl.1993.641

  日期：1993.4

  Protonated heteroaromatic bases were easily alkylated via radical pathways using alkyl halides in the presence of tris(trimethylsilyl)silane under photochemical or thermal conditions.

  在三（三甲基甲硅烷基）硅烷的存在下，在光化学或热条件下，质子化的杂芳族碱很容易通过自由基途径使用烷基卤化物进行烷基化。