2-((7-chloroquinolin-4-yl)amino)ethyl methanesulfonate | 852402-04-1

分子结构分类

有机化合物 - 有机杂环化合物 - 喹啉及其衍生物

中文名称

——

中文别名

——

英文名称

2-((7-chloroquinolin-4-yl)amino)ethyl methanesulfonate

英文别名

2-[(7-Chloroquinolin-4-yl)amino]ethyl methanesulfonate

CAS

852402-04-1

化学式

C₁₂H₁₃ClN₂O₃S

mdl

——

分子量

300.766

InChiKey

XCHVSVATQCDPNN-UHFFFAOYSA-N

BEILSTEIN

——

EINECS

——

计算性质

辛醇/水分配系数(LogP)：

2.3
重原子数：

19
可旋转键数：

5
环数：

2.0
sp3杂化的碳原子比例：

0.25
拓扑面积：

76.7
氢给体数：

1
氢受体数：

5

上下游信息

上游原料

中文名称	英文名称	CAS号	化学式	分子量
2-(7-氯喹啉-4-氨基)乙醇	3-(7-chloroquinolin-4-ylamino)propyl alcohol	91066-18-1	C₁₁H₁₁ClN₂O	222.674

下游产品

中文名称	英文名称	CAS号	化学式	分子量
——	N-(2-azidoethyl)-7-chloroquinolin-4-amine	1145669-30-2	C₁₁H₁₀ClN₅	247.687
——	3-[(7-chloroquinolin-4-yl)amino]azidopropane	1236121-98-4	C₁₂H₁₂ClN₅	261.714
——	2-((2-((7-chloroquinolin-4-yl)amino)ethyl)(methyl)amino)ethan-1-ol	1415338-54-3	C₁₄H₁₈ClN₃O	279.769
——	{1-[2-(7-chloroquinolin-4-ylamino)ethyl]-1H-[1,2,3]triazol-4-yl}methanol	1335447-15-8	C₁₄H₁₄ClN₅O	303.751
——	7-chloro-N-(2-(4-(4,6-di(piperidin-1-yl)-1,3,5-triazin-2-yl)piperazin-1-yl)ethyl)quinolin-4-amine	1099811-62-7	C₂₈H₃₈ClN₉	536.123
——	N-(2-(4-benzhydrylpiperazin-1-yl)ethyl)-7-chloroquinolin-4-amine	——	C₂₈H₂₉ClN₄	457.018
——	4-[4-[4-[2-[(7-Chloroquinolin-4-yl)amino]ethyl]piperazin-1-yl]-6-morpholin-4-yl-1,3,5-triazin-2-yl]piperazine-1-carbaldehyde	1099811-66-1	C₂₇H₃₅ClN₁₀O₂	567.094
——	7-chloro-N-[2-(3,4-dihydro-1H-isoquinolin-2-yl)ethyl]quinolin-4-amine	1259436-81-1	C₂₀H₂₀ClN₃	337.852
——	7-chloro-N-[2-[4-[4-(cyclohexylamino)-6-piperidin-1-yl-1,3,5-triazin-2-yl]piperazin-1-yl]ethyl]quinolin-4-amine	1099811-64-9	C₂₉H₄₀ClN₉	550.15
——	1-[2-[(7-Chloro-4-quinolyl)amino]ethyl]-4-phenyl-piperidine-4-carbonitrile	1259436-83-3	C₂₃H₂₃ClN₄	390.915
——	6-[4-[2-[(7-chloroquinolin-4-yl)amino]ethyl]piperazin-1-yl]-2-N,4-N-diphenyl-1,3,5-triazine-2,4-diamine	1099811-46-7	C₃₀H₃₀ClN₉	552.082
——	7-chloro-N-(2-(4-(2-nitrophenyl)piperazin-1-yl)ethyl)quinolin-4-amine	1259436-75-3	C₂₁H₂₂ClN₅O₂	411.891
——	N-[2-[4-[4-anilino-6-(4-ethylpiperazin-1-yl)-1,3,5-triazin-2-yl]piperazin-1-yl]ethyl]-7-chloroquinolin-4-amine	1099811-47-8	C₃₀H₃₇ClN₁₀	573.144
——	6-(4-(2-((7-chloroquinolin-4-yl)amino)ethyl)piperazin-1-yl)-N²,N⁴-di-p-tolyl-1,3,5-triazine-2,4-diamine	1099811-55-8	C₃₂H₃₄ClN₉	580.135
——	7-chloro-N-[2-[4-[4-(4-ethylpiperazin-1-yl)-6-(4-methylanilino)-1,3,5-triazin-2-yl]piperazin-1-yl]ethyl]quinolin-4-amine	1099811-54-7	C₃₁H₃₉ClN₁₀	587.171
——	{2-[4-(4-chlorophenoxymethyl)-[1,2,3]triazol-1-yl]-ethyl}-(7-chloroquinolin-4-yl)amine	1335447-27-2	C₂₀H₁₇Cl₂N₅O	414.294
——	N-[2-[4-(4-anilino-6-morpholin-4-yl-1,3,5-triazin-2-yl)piperazin-1-yl]ethyl]-7-chloroquinolin-4-amine	1099811-45-6	C₂₈H₃₂ClN₉O	546.075
——	(7-chloroquinolin-4-yl)-[2-(4-p-tolyloxymethyl-[1,2,3]triazol-1-yl)ethyl]amine	1335447-32-9	C₂₁H₂₀ClN₅O	393.876
——	{2-[4-(4-bromophenoxymethyl)-[1,2,3]triazol-1-yl]ethyl}-(7-chloroquinolin-4-yl)amine	1335447-24-9	C₂₀H₁₇BrClN₅O	458.745
——	N-[2-[4-(4-anilino-6-piperidin-1-yl-1,3,5-triazin-2-yl)piperazin-1-yl]ethyl]-7-chloroquinolin-4-amine	1099811-43-4	C₂₉H₃₄ClN₉	544.102
——	(7-chloroquinolin-4-yl)-{2-[4-(naphthalen-2-yloxymethyl)-[1,2,3]triazol-1-yl]ethyl}amine	1335447-46-5	C₂₄H₂₀ClN₅O	429.909
——	6-(4-(2-((7-chloroquinolin-4-yl)amino)ethyl)piperazin-1-yl)-N²,N⁴-di-o-tolyl-1,3,5-triazine-2,4-diamine	1099811-49-0	C₃₂H₃₄ClN₉	580.135
——	6-[4-[2-[(7-chloroquinolin-4-yl)amino]ethyl]piperazin-1-yl]-2-N-cyclohexyl-4-N-phenyl-1,3,5-triazine-2,4-diamine	1099811-44-5	C₃₀H₃₆ClN₉	558.129
——	(7-chloroquinolin-4-yl)-{2-[4-(tetrahydropyran-2-yloxymethyl)-[1,2,3]triazol-1-yl]ethyl}amine	1335447-23-8	C₁₉H₂₂ClN₅O₂	387.869
——	(7-chloroquinolin-4-yl)-{2-[4-(2,6-dichlorophenoxymethyl)-[1,2,3]triazol-1-yl]ethyl}amine	1335447-29-4	C₂₀H₁₆Cl₃N₅O	448.739
——	7-chloro-N-[2-[4-[4-(4-methylanilino)-6-morpholin-4-yl-1,3,5-triazin-2-yl]piperazin-1-yl]ethyl]quinolin-4-amine	1099811-53-6	C₂₉H₃₄ClN₉O	560.102
——	(7-chloroquinolin-4-yl)-[2-(4-m-tolyloxymethyl-[1,2,3]triazol-1-yl)ethyl]amine	1335447-34-1	C₂₁H₂₀ClN₅O	393.876
——	(7-chloroquinolin-4-yl)-{2-[4-(4-isopropylphenoxymethyl)-[1,2,3]triazol-1-yl]ethyl}amine	1335447-38-5	C₂₃H₂₄ClN₅O	421.929
——	7-chloro-N-[2-[4-[4-(4-fluoroanilino)-6-piperidin-1-yl-1,3,5-triazin-2-yl]piperazin-1-yl]ethyl]quinolin-4-amine	1099811-56-9	C₂₉H₃₃ClFN₉	562.093
——	7-chloro-N-[2-[4-[4-(4-methylanilino)-6-(4-phenylpiperazin-1-yl)-1,3,5-triazin-2-yl]piperazin-1-yl]ethyl]quinolin-4-amine	1099811-51-4	C₃₅H₃₉ClN₁₀	635.215
——	7-chloro-N-[2-[4-(5-methyl-2-nitro-phenyl)piperazin-1-yl]ethyl]quinolin-4-amine	1259436-77-5	C₂₂H₂₄ClN₅O₂	425.918
——	6-[4-[2-[(7-chloroquinolin-4-yl)amino]ethyl]piperazin-1-yl]-2-N-cyclohexyl-4-N-(4-fluorophenyl)-1,3,5-triazine-2,4-diamine	1099811-57-0	C₃₀H₃₅ClFN₉	576.12
——	6-[4-[2-[(7-chloroquinolin-4-yl)amino]ethyl]piperazin-1-yl]-2-N-cyclohexyl-4-N-(4-methylphenyl)-1,3,5-triazine-2,4-diamine	1099811-52-5	C₃₁H₃₈ClN₉	572.156
——	(7-chloroquinolin-4-yl)-{2-[4-(4-nitrophenoxymethyl)-[1,2,3]triazol-1-yl]ethyl}amine	1335447-40-9	C₂₀H₁₇ClN₆O₃	424.846
——	7-chloro-N-[2-[4-[4-(2-methylanilino)-6-morpholin-4-yl-1,3,5-triazin-2-yl]piperazin-1-yl]ethyl]quinolin-4-amine	1099811-48-9	C₂₉H₃₄ClN₉O	560.102
——	1-(4-{1-[2-(7-chloroquinolin-4-ylamino)ethyl]-1H-[1,2,3]triazol-4-ylmethoxy}phenyl)ethanone	1335447-41-0	C₂₂H₂₀ClN₅O₂	421.886
——	7-chloro-N-(2-(4-(dipyridin-2-ylmethyleneamino)piperidin-1-yl)ethyl)quinolin-4-amine	1239953-63-9	C₂₇H₂₇ClN₆	471.005
——	(7-chloroquinolin-4-yl)-{2-[4-(3,4-dimethylphenoxymethyl)-[1,2,3]triazol-1-yl]ethyl}amine	1335447-36-3	C₂₂H₂₂ClN₅O	407.903
——	7-chloro-N-[2-[4-[4-(2-fluoroanilino)-6-piperidin-1-yl-1,3,5-triazin-2-yl]piperazin-1-yl]ethyl]quinolin-4-amine	1099811-60-5	C₂₉H₃₃ClFN₉	562.093

反应信息

作为反应物：

描述：

2-((7-chloroquinolin-4-yl)amino)ethyl methanesulfonate 在 sodium azide 作用下，反应 8.0h，生成 N-(2-azidoethyl)-7-chloroquinolin-4-amine