(E)-N-(3-acetamidopropyl)-cinnamamide | 1442435-88-2

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 英文名称: (E)-N-(3-acetamidopropyl)-cinnamamide
• 英文别名: (E)-N-(3-acetamidopropyl)-3-phenylprop-2-enamide
• CAS: 1442435-88-2
• 化学式: C₁₄H₁₈N₂O₂
• 分子量: 246.309
• InChiKey: ZBHVCVVWZRRCHE-CMDGGOBGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  18
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  58.2
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  N-乙酰基-1,3-丙二胺 、 肉桂酸 、 乙酸酐 在 N,N'-二环己基碳二亚胺 作用下， 以 氯仿 为溶剂， 反应 9.0h， 以96%的产率得到(E)-N-(3-acetamidopropyl)-cinnamamide
  参考文献：
  名称：

  A new asymmetric diamide from the seed cake of Jatropha curcas L.

  摘要：

  A new asymmetric diamide (E)-N-(3-acetamidopropyl)-cinnamamide named curcamide (1) has been isolated from the ethanol extract of the seed cake of Jatropha curcas L. along with 7 known compounds identified as isoamericanin (2), isoprincepin (3), caffeoylaldehyde (4), isoferulaldehyde (5), glycerol monooleate (6), syringaldehyde (7), and beta-ethyl-o-glucopyranoside (8). The synthesis and antibacterial activity of the new compound have been also studied. (C) 2012 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.fitote.2012.04.001

文献信息

• A new asymmetric diamide from the seed cake of Jatropha curcas L.
  作者：Licheng Yao、Changri Han、Guangying Chen、Xiaoping Song、Yonghui Chang、Wenxia Zang

  DOI：10.1016/j.fitote.2012.04.001

  日期：2012.12

  A new asymmetric diamide (E)-N-(3-acetamidopropyl)-cinnamamide named curcamide (1) has been isolated from the ethanol extract of the seed cake of Jatropha curcas L. along with 7 known compounds identified as isoamericanin (2), isoprincepin (3), caffeoylaldehyde (4), isoferulaldehyde (5), glycerol monooleate (6), syringaldehyde (7), and beta-ethyl-o-glucopyranoside (8). The synthesis and antibacterial activity of the new compound have been also studied. (C) 2012 Elsevier B.V. All rights reserved.