Desacetylipecosid | 21618-62-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: Desacetylipecosid
• 英文别名: deacetylipecoside；methyl (2S,3R,4S)-4-[[(1R)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl]-3-ethenyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,4-dihydro-2H-pyran-5-carboxylate
• CAS: 21618-62-2；69400-51-7
• 化学式: C₂₅H₃₃NO₁₁
• 分子量: 523.537
• InChiKey: MTAVTRZTGFLKSC-MDXCLUIBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  37
• 可旋转键数：
  8
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  187
• 氢给体数：
  7
• 氢受体数：
  12

反应信息

• 作为反应物：
  描述：

  重氮甲烷 、 Desacetylipecosid 在 desacetylisoipecoside 作用下， 以 甲醇 为溶剂， 以40.2 mg的产率得到Methylisoalangisid
  参考文献：
  名称：

  Hoefle, Gerhard; Nagakura, Naotaka; Zenk, Meinhart H., Chemische Berichte, 1980, vol. 113, # 2, p. 566 - 576

  摘要：

  DOI：
• 作为产物：
  描述：

  多巴胺 、 开联番木鳖苷 在 deacetylipecoside synthase 、 三(羟甲基)甲基甘氨酸 、 D-glucurono-3,6-lactone 作用下， 以 sodium hydroxide 为溶剂， 生成 Desacetylipecosid
  参考文献：
  名称：

  来自 Alangium lamarckii Thw 的脱乙酰基佩克苷合酶的纯化和表征。

  摘要：

  脱乙酰基多糖苷合酶 (DIS) 是一种催化多巴胺和 secologanin 缩合形成脱乙酰基多糖苷的 (R)-差向异构体的酶，已从 Alangium lamarckii 的叶子中纯化 570 倍，并进行了部分表征。分离的酶是单一多肽，Mr 为 30,000，最适 pH 值为 7.5，最适温度为 45 摄氏度。多巴胺和赛洛加宁的表观 Km 值分别为 0.7 和 0.9 mM。DIS 对多巴胺表现出高底物特异性，而既不利用酪胺也不利用色胺。酶活性不受其底物多巴胺的抑制，但被具有 10 microM 的类似 I50 值的 alangimakine 和 dehydroalangimakine 抑制。

  DOI：

  10.1016/s0031-9422(00)00260-0

文献信息

• Enzymatic Biosensors With Enhanced Activity Retention For Detection Of Organic Compounds
  申请人：REARDON Kenneth F.

  公开号：US20090221014A1

  公开（公告）日：2009-09-03

  Enzymatic biosensors and methods of producing distal tips for biosensor transducers for use in detecting one or more analytes selected from organic compounds susceptible to dehalogenation, organic compounds susceptible to oxygenation, organic compounds susceptible to deamination, organosulfate compounds susceptible to hydrolysis, and organophosphate compounds susceptible to hydrolysis are disclosed herein, as well as biosensor arrays, methods of detecting and quantifying analytes within a mixture, and devices and methods for delivering reagents to enzymes disposed within the distal tip of a biosensor.
• CONSTRUCTS AND METHODS FOR BIOSYNTHESIS OF GALANTHAMINE
  申请人：Donald Danforth Plant Science Center

  公开号：US20190300892A1

  公开（公告）日：2019-10-03

  The present disclosure relates generally to the identification of biosynthetic pathway genes. In particular, it relates to the identification of enzymes within the Amaryllidaceae alkaloid biosynthetic pathway as well as to engineering transgenic organisms for the production of galanthamine and/or hemanthamine and/or lycorine.
• US8323956B2
  申请人：——

  公开号：US8323956B2

  公开（公告）日：2012-12-04
• [EN] ENZYMATIC BIOSENSORS WITH ENHANCED ACTIVITY RETENTION FOR DETECTION OF ORGANIC COMPOUNDS<br/>[FR] BIOCAPTEURS ENZYMATIQUES À RÉTENTION D'ACTIVITÉ ACCRUE POUR LA DÉTECTION DE COMPOSÉS ORGANIQUES
  申请人：UNIV COLORADO STATE RES FOUND

  公开号：WO2009126841A1

  公开（公告）日：2009-10-15

  Enzymatic biosensors and methods of producing distal tips for biosensor transducers for use in detecting one or more analytes selected from organic compounds susceptible to dehalogenation, organic compounds susceptible to oxygenation, organic compounds susceptible to deamination, organosulfate compounds susceptible to hydrolysis, and organophosphate compounds susceptible to hydrolysis are disclosed herein, as well as biosensor arrays, methods of detecting and quantifying analytes within a mixture, and devices and methods for delivering reagents to enzymes disposed within the distal tip of a biosensor.
• Hoefle, Gerhard; Nagakura, Naotaka; Zenk, Meinhart H., Chemische Berichte, 1980, vol. 113, # 2, p. 566 - 576
  作者：Hoefle, Gerhard、Nagakura, Naotaka、Zenk, Meinhart H.

  DOI：——

  日期：——