N-trans-feruloyl-4'-O-methyldopamine | 78510-20-0

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 英文名称: N-trans-feruloyl-4'-O-methyldopamine
• 英文别名: N-trans-m-coumaroyl-4-methyldopamine；N-trans-feruloyl 4-O-methyldopamine；N-trans-feruloyl-4-O-methyldopamine；N-trans-feruloyl-4-methyldopamine；(E)-3-(4-hydroxy-3-methoxyphenyl)-N-[2-(3-hydroxy-4-methoxyphenyl)ethyl]prop-2-enamide
• CAS: 78510-20-0
• 化学式: C₁₉H₂₁NO₅
• 分子量: 343.379
• InChiKey: ACSWAJLDOHJFNA-VMPITWQZSA-N

物化性质

• 沸点：
  620.7±55.0 °C(Predicted)
• 密度：
  1.248±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  25
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.21
• 拓扑面积：
  88
• 氢给体数：
  3
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  阿魏酸 、 5-(2-氨基乙基)-2-甲氧基苯酚 在 N,N'-二环己基碳二亚胺 作用下， 以 四氢呋喃 为溶剂， 以38%的产率得到N-trans-feruloyl-4'-O-methyldopamine
  参考文献：
  名称：

  来自长叶放线菌的酚酰胺

  摘要：

  摘要 对长叶放线菌的进一步研究导致分离出一种新的酚酰胺、N-反式阿魏酰 3-甲基多巴胺以及 N-反式阿魏酰酪胺。通过光谱和化学手段阐明了该化合物的结构。

  DOI：

  10.1016/s0031-9422(00)98022-1

文献信息

• Synthesis of phenolic amides and evaluation of their antioxidant and anti-inflammatory activity in vitro and in vivo
  作者：Ya-Ting Lee、You-Liang Hsieh、Yen-Hung Yeh、Chih-Yang Huang

  DOI：10.1039/c5ra14137k

  日期：——

  15 phenolic amides (PAs) have been synthesized and examinedin vitrousing four tests: (1) prevention of Cu²⁺-induced human low-density lipoprotein oxidation, (2) scavenging of stable radicals, (3) anti-inflammatory activity, and (4) scavenging of superoxide radicals.

  已合成和检验了15种酚酰胺（PAs），使用四种测试方法：in vitro（1）预防Cu²⁺诱导的人类低密度脂蛋白氧化，（2）稳定自由基清除，（3）抗炎活性和（4）清除超氧自由基。
• TANAKA, HITOSHI;NAKAMURA, TAKESHI;ICHINO, KAZUHIKO;ITO, KAZUO, PHYTOCHEMISTRY, 28,(1989) N, C. 2516-2517
  作者：TANAKA, HITOSHI、NAKAMURA, TAKESHI、ICHINO, KAZUHIKO、ITO, KAZUO

  DOI：——

  日期：——
• COMPOSITIONS AND METHODS TO CONTROL OOMYCETE FUNGAL PATHOGENS
  申请人：Dow AgroSciences LLC

  公开号：EP2278882A2

  公开（公告）日：2011-02-02
• [EN] COMPOSITIONS AND METHODS TO CONTROL OOMYCETE FUNGAL PATHOGENS<br/>[FR] COMPOSITIONS ET PROCÉDÉS POUR LUTTER CONTRE LES PATHOGÈNES FONGIQUES OOMYCÈTES
  申请人：DOW AGROSCIENCES LLC

  公开号：WO2009146079A2

  公开（公告）日：2009-12-03

  The present invention relates to compounds and the use of such compounds for increasing the efficacy of fungicides for controlling oomycete pathogen induced disease or diseases in one or more plants.
• [EN] COMPOSITIONS AND METHODS TO CONTROL OOMYCETE FUNGAL PATHOGENS<br/>[FR] COMPOSITIONS ET PROCÉDÉS POUR LUTTER CONTRE DES PATHOGÈNES FONGIQUES OOMYCÈTES
  申请人：DOW AGROSCIENCES LLC

  公开号：WO2011047025A1

  公开（公告）日：2011-04-21

  The present invention relates to fungicidal compositions and their use for controlling oomycete pathogen induced disease or diseases in one or more plants The inventive methods comprise contacting a plant at risk of being diseased from an oomycete pathogen that produces zoospores with a composition comprising an effective amount of a fungicide, at least one of a zoospore attractant and a zoospore attractant derivative, one or more binders and optionally, other inert formulation ingredients Alternatively, the composition of the present invention may be comprised of differing zoospore attractants and zoospore attractant derivatives as well as a mixture of differing fungicides.