(2-hydroxy-7,7-dimethylbicyclo[2.2.1]heptan-1-yl)methanesulfonic acid | 791002-19-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: (2-hydroxy-7,7-dimethylbicyclo[2.2.1]heptan-1-yl)methanesulfonic acid
• 英文别名: 2-hydroxy-bornane-10-sulfonic acid；Camphanol-(2)-sulfonsaeure-(1¹)；2-Oxy-1.7.7-trimethyl-bicyclo-[1.2.2]-heptan-sulfonsaeure-(1¹)；2-Oxy-camphan-sulfonsaeure-(10)；2-Hydroxy-bornan-10-sulfonsaeure；(2-Hydroxy-7,7-dimethyl-1-bicyclo[2.2.1]heptanyl)methanesulfonic acid
• CAS: 791002-19-2
• 化学式: C₁₀H₁₈O₄S
• 分子量: 234.317
• InChiKey: UVNMGCYEZKGPLX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  83
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  (2-hydroxy-7,7-dimethylbicyclo[2.2.1]heptan-1-yl)methanesulfonic acid 在 盐酸 、 溶剂黄146 作用下， 生成 3A,7a-dimethyl-hexahydro-4,7-methano-benz[d][1,2]oxathiol-2,2-dioxide
  参考文献：
  名称：

  Lipp; Holl, Chemische Berichte, 1929, vol. 62, p. 501

  摘要：

  DOI：
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 乙醇 、 sodium 作用下， 生成 (2-hydroxy-7,7-dimethylbicyclo[2.2.1]heptan-1-yl)methanesulfonic acid
  参考文献：
  名称：

  Lipp; Holl, Chemische Berichte, 1929, vol. 62, p. 501

  摘要：

  DOI：

文献信息

• Ruthenium complexes of phosphine–amide based ligands as efficient catalysts for transfer hydrogenation reactions
  作者：Samanta Yadav、Paranthaman Vijayan、Sunil Yadav、Rajeev Gupta

  DOI：10.1039/d0dt04401f

  日期：——

  mononuclear Ru(II) complexes of tridentate phosphine–carboxamide based ligands providing a NNP coordination environment. The octahedral Ru(II) ion shows additional coordination with co-ligands; CO, Cl and CH3OH. All three Ru(II) complexes were thoroughly characterized including their crystal structures. These Ru(II) complexes were utilized as catalysts for the transfer hydrogenation of assorted carbonyl

  这项工作提出了三齿膦-羧酰胺基配体的三种单核Ru（II）配合物，提供了NNP配位环境。八面体Ru（II）离子显示出与共配体的额外配位；CO，Cl和CH 3 OH。三种Ru（II）配合物都被彻底表征，包括其晶体结构。这些Ru（II配合物被用作催化剂，使用异丙醇作为氢源，对各种羰基化合物（包括一些具有挑战性的生物学相关底物）进行转移加氢。结合研究表明，通过取代Ru-连接的氯离子，然后生成Ru-H中间体，异丙醇离子的配位被分离和表征，并被发现参与催化。
• PROCESS FOR THE MANUFACTURE OF CHIRAL CATALYSTS AND THEIR SALTS
  申请人：Scinopharm Taiwan, LTD.

  公开号：US20130150574A1

  公开（公告）日：2013-06-13

  The present invention provides efficient and economical methods for synthesis of (−)-2-exo-morpholinoisoborne-10-thiol, its enantiomer, and related chiral catalysts. Novel compounds and methods of asymmetric synthesis are also disclosed.

  本发明提供了合成(−)-2-exo-morpholinoisoborne-10-thiol及其对映异构体和相关手性催化剂的高效经济方法。还公开了新型化合物和不对称合成方法。
• ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM, PATTERN FORMING METHOD, MANUFACTURING METHOD OF ELECTRONIC DEVICE USING THE SAME, AND ELECTRONIC DEVICE
  申请人：FUJIFILM CORPORATION

  公开号：US20150185612A1

  公开（公告）日：2015-07-02

  There is provided an actinic ray-sensitive or radiation-sensitive resin composition comprising: (A) a resin having a repeating unit represented by the specific formula and a group capable of decomposing by an action of an acid to produce a polar group; and an ionic compound represented by the specific formula, and a resist film comprising the actinic ray-sensitive or radiation-sensitive resin composition.

  提供一种光致射线敏感或辐射敏感的树脂组合物，包括：（A）具有特定公式表示的重复单元和能够通过酸作用分解产生极性基团的基团的树脂；以及具有特定公式表示的离子化合物，以及包括该光致射线敏感或辐射敏感的树脂组合物的抗蚀膜。
• [EN] ENANTIOSELECTIVE ALKENYLATION OF ALDEHYDES<br/>[FR] ALCÉNYLATION ÉNANTIOSÉLECTIVE D'ALDÉHYDES
  申请人：AMGEN INC

  公开号：WO2022115400A1

  公开（公告）日：2022-06-02

  Provided herein are processes for synthesizing intermediates useful in preparing Mcl-1 inhibitors. In particular, provided herein are processes for synthesizing compound IA, wherein R1is described herein. Compound IA can be useful in synthesizing compound A1, or a salt or solvate thereof, and compound A2, or a salt of solvate thereof.

  本文提供了一些合成中间体的过程，这些中间体对于制备Mcl-1抑制剂非常有用。具体来说，本文提供了合成化合物IA的过程，其中R1在此处描述。化合物IA可以用于合成化合物A1或其盐或溶剂，以及化合物A2或其盐或溶剂。
• Resist composition and method for forming resist pattern
  申请人：TOKYO OHKA KOGYO CO., LTD.

  公开号：US10241406B2

  公开（公告）日：2019-03-26

  A resist composition containing a resin component having a structural unit represented by general formula (a0-1), and a compound represented by general formula (b1). In general formula (a0-1), R is a hydrogen atom, an alkyl group, or a halogenated alkyl group. Va1 is a divalent hydrocarbon group. na1 represents an integer of 0 to 2. Ra′12 and Ra′13 are a monovalent chain saturated hydrocarbon group having 1 to 10 carbon atoms or a hydrogen atom. Ra′14 is a phenyl group, a naphthyl group, or an anthryl group. In general formula (b1), Rb1 represents a cyclic hydrocarbon group. Yb1 represents a divalent linking group containing an ester bond. Vb1 represents an alkylene group, a fluorinated alkylene group, or a single bond. m is an integer of 1 or more, and Mm+ is an m-valent organic cation.

  一种抗蚀剂组合物，含有具有通式（a0-1）表示的结构单元的树脂成分和通式（b1）表示的化合物。在通式（a0-1）中，R 是氢原子、烷基或卤代烷基。Va1是二价烃基，na1代表0至2的整数。 Ra′12和Ra′13是具有1至10个碳原子的单价链饱和烃基或氢原子。Ra′14 是苯基、萘基或蒽基。通式（b1）中，Rb1 代表环状烃基。Yb1 代表含有酯键的二价连接基团。Vb1 代表亚烷基、氟化亚烷基或单键。m 为 1 或 1 以上的整数，Mm+ 为 m 价有机阳离子。