1,2-Di-(p-methoxyphenyl)-4-phenyl-butan-1,4-dion | 21757-10-8

• 分子结构分类: 有机化合物 - 木脂素、新木脂素和相关化合物
• 英文名称: 1,2-Di-(p-methoxyphenyl)-4-phenyl-butan-1,4-dion
• 英文别名: 1,2-Bis(4-methoxyphenyl)-4-phenyl-1,4-butanedione；1,2-bis(4-methoxyphenyl)-4-phenylbutane-1,4-dione
• CAS: 21757-10-8
• 化学式: C₂₄H₂₂O₄
• 分子量: 374.436
• InChiKey: YSOBXGPXNAQWAJ-UHFFFAOYSA-N

物化性质

• 熔点：
  129-131 °C(Solvent: Acetone; Hexane)
• 沸点：
  555.1±50.0 °C(predicted)
• 密度：
  1.159±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  28
• 可旋转键数：
  8
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  二甲氧基苯甲醇 在 pyridinium chlorochromate 作用下， 以 四氢呋喃 、 二氯甲烷 、 苯 为溶剂， 反应 34.0h， 生成 1,2-Di-(p-methoxyphenyl)-4-phenyl-butan-1,4-dion
  参考文献：
  名称：

  UV Light-Mediated Difunctionalization of Alkenes through Aroyl Radical Addition/1,4-/1,2-Aryl Shift Cascade Reactions

  摘要：

  UV light-mediated difunctionalization of alkenes through an aroyl radical addition/1,4-/1,2-aryl shift has been described. The resulted aroyl radical from a photocleavage reaction added to acrylamide compounds followed by cyclization led to the formation of oxindoles, whereas the addition to cinnamic amides aroused a unique 1,4-aryl shift reaction. Furthermore, the difunctionalization of alkenes of prop-2-en-1-ols was also achieved through aroyl radical addition and a sequential 1,2-aryl shift cascade reaction.

  DOI：

  10.1021/acs.orglett.5b00144

文献信息

• Canevet,J.C.; Graff,Y., Bulletin de la Societe Chimique de France, 1978, vol. <II>, p. 278 - 282
  作者：Canevet,J.C.、Graff,Y.

  DOI：——

  日期：——
• CANEVET J. C.; GRAFF Y., BULL. SOC. CHIM. FRANCE, 1978, PART 2, NO 5-6, 278-282
  作者：CANEVET J. C.、 GRAFF Y.

  DOI：——

  日期：——
• UV Light-Mediated Difunctionalization of Alkenes through Aroyl Radical Addition/1,4-/1,2-Aryl Shift Cascade Reactions
  作者：Lewei Zheng、Hongli Huang、Chao Yang、Wujiong Xia

  DOI：10.1021/acs.orglett.5b00144

  日期：2015.2.20

  UV light-mediated difunctionalization of alkenes through an aroyl radical addition/1,4-/1,2-aryl shift has been described. The resulted aroyl radical from a photocleavage reaction added to acrylamide compounds followed by cyclization led to the formation of oxindoles, whereas the addition to cinnamic amides aroused a unique 1,4-aryl shift reaction. Furthermore, the difunctionalization of alkenes of prop-2-en-1-ols was also achieved through aroyl radical addition and a sequential 1,2-aryl shift cascade reaction.