2,6R,10-trimethyl-2,9-undecadien-1-al | 113301-27-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 2,6R,10-trimethyl-2,9-undecadien-1-al
• 英文别名: (2E)-2,6,10-trimethylundeca-2,9-dienal
• CAS: 113301-27-2
• 化学式: C₁₄H₂₄O
• 分子量: 208.344
• InChiKey: FZRDVGSDXJJFNY-GXDHUFHOSA-N

物化性质

• 沸点：
  308.0±21.0 °C(Predicted)
• 密度：
  0.853±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  15
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.64
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  4,8-二甲基壬-7-烯醛 在 盐酸 作用下， 以 四氢呋喃 、 乙醚 为溶剂， 反应 3.5h， 生成 2,6R,10-trimethyl-2,9-undecadien-1-al
  参考文献：
  名称：

  Phosphonates α-lithies agents de transfert fonctionnel. Preparation d'aldehydes α,β-insatures α-substitues

  摘要：

  DOI：

  10.1016/s0040-4039(00)95341-3

文献信息

• CATALYST FOR ASYMMETRIC HYDROGENATION AND METHOD FOR MANUFACTURING OPTICALLY ACTIVE CARBONYL COMPOUND USING THE SAME
  申请人：YAMADA Shinya

  公开号：US20120136176A1

  公开（公告）日：2012-05-31

  The present invention provides a catalyst used for manufacturing an optically active carbonyl compound by selective asymmetric hydrogenation of an α,β-unsaturated carbonyl compound, which is insoluble in a reaction mixture, and a method for manufacturing the corresponding optically active carbonyl compound. Particularly, the invention provides a catalyst for obtaining an optically active citronellal useful as a flavor or fragrance, by selective asymmetric hydrogenation of citral, geranial or neral. The invention relates to a catalyst for asymmetric hydrogenation of an α,β-unsaturated carbonyl compound, which comprises: a powder of at least one metal selected from metals belonging to Group 8 to Group 10 of the Periodic Table, or a metal-supported substance in which the at least one metal is supported on a support; an optically active peptide compound; and an acid, and also relates to a method for manufacturing an optically active carbonyl compound using the same.

  本发明提供了一种用于通过选择性不对称加氢α，β-不饱和羰基化合物制备光学活性羰基化合物的催化剂，该催化剂在反应混合物中不溶解，并提供了制备相应光学活性羰基化合物的方法。特别地，该发明提供了一种催化剂，通过选择性不对称加氢柠檬醛、香叶醛或柠檬醛制备出用作香料或芳香剂的光学活性香茅醛。该发明涉及一种用于不对称加氢α，β-不饱和羰基化合物的催化剂，包括：来自周期表第8至第10族金属中至少一种金属的粉末，或者至少一种金属负载物质，其中至少一种金属负载在一种载体上；一种光学活性肽化合物；和一种酸，还涉及使用该催化剂制备光学活性羰基化合物的方法。
• CATALYST FOR ASYMMETRIC HYDROGENATION
  申请人：MAEDA Hironori

  公开号：US20100324338A1

  公开（公告）日：2010-12-23

  This invention aims at providing a catalyst for producing an optically active aldehyde or an optically active ketone, which is an optically active carbonyl compound, by carrying out selective asymmetric hydrogenation of an α,β-unsaturated carbonyl compound, particularly a catalyst which is insoluble in a reaction mixture for obtaining optically active citronellal which is useful as a flavor or fragrance, by carrying out selective asymmetric hydrogenation of citral, geranial or neral; and a method for producing a corresponding optically active carbonyl compound. The invention relates to a catalyst for asymmetric hydrogenation of an α,β-unsaturated carbonyl compound, which comprises a powder of at least one metal selected from metals belonging to Group 8 to Group 10 of the Periodic Table, or a metal-supported substance in which at least one metal selected from metals belonging to Group 8 to Group 10 of the Periodic Table is supported on a support, an optically active cyclic nitrogen-containing compound and an acid.

  这项发明旨在通过对α，β-不饱和羰基化合物进行选择性不对称加氢，特别是通过对柠檬醛、香叶醛或柠檬醛进行选择性不对称加氢，从而提供用作香料或香精的有用的光学活性香茅醛的催化剂，该香茅醛是一种光学活性羰基化合物；以及生产相应的光学活性羰基化合物的方法。该发明涉及一种用于不对称加氢α，β-不饱和羰基化合物的催化剂，其包括来自周期表第8至第10族金属中至少一种金属的粉末，或者至少一种来自周期表第8至第10族金属的金属负载物质，该金属负载在一种支撑物上，还包括光学活性的含氮环化合物和酸。
• Process for preparing epoxide-cyclohexyl compound and resultant compound
  申请人：Hoffmann-La Roche Inc.

  公开号：US04000131A1

  公开（公告）日：1976-12-28

  Homologation of .alpha.,.beta.-polyene unsaturated aldehydes and ketones to form .alpha.,.beta.-unsaturated aldehydes via epoxidation of the ketone or aldehyde and intermediates in this process such as .beta.,.gamma.-unsaturated polyene aldehydes.

  通过对.alpha.,.beta.-聚烯烃不饱和醛和酮进行同源化，以形成.alpha.,.beta.-不饱和醛，通过对酮或醛和此过程中的中间体进行环氧化，如.beta.,.gamma.-不饱和聚烯烃醛。
• Catalyst for asymmetric hydrogenation comprising peptides and method for manufacturing optically active carbonyl compound using the same
  申请人：Takasago International Corporation

  公开号：EP2457655A2

  公开（公告）日：2012-05-30

  The present invention provides a catalyst used for manufacturing an optically active carbonyl compound by selective asymmetric hydrogenation of an α, β-unsaturated carbonyl compound, which is insoluble in a reaction mixture, and a method for manufacturing the corresponding optically active carbonyl compound. Particularly, the invention provides a catalyst for obtaining an optically active citronellal useful as a flavor or fragrance, by selective asymmetric hydrogenation of citral, geranial or neral. The invention relates to a catalyst for asymmetric hydrogenation of an α, β-unsaturated carbonyl compound, which comprises: a powder of at least one metal selected from metals belonging to Group 8 to Group 10 of the Periodic Table, or a metal-supported substance in which the at least one metal is supported on a support; an optically active peptide compound; and an acid, and also relates to a method for manufacturing an optically active carbonyl compound using the same.

  本发明提供了一种通过选择性不对称氢化不溶于反应混合物中的α，β-不饱和羰基化合物来制造光学活性羰基化合物的催化剂，以及制造相应光学活性羰基化合物的方法。特别是，本发明提供了一种催化剂，通过对柠檬醛、香叶醇或橙花醛的选择性不对称氢化，获得光学活性香茅醛，用作香精或香料。本发明涉及一种用于α，β-不饱和羰基化合物不对称氢化的催化剂，它包括：至少一种选自属于元素周期表第8组至第10组的金属的粉末，或其中至少一种金属被支撑在支撑物上的金属支撑物质；一种光学活性肽化合物；以及一种酸，还涉及一种使用该催化剂制造光学活性羰基化合物的方法。
• USE OF ASYMMETRIC HYDROGENATION CATALYST
  申请人：Takasago International Corporation

  公开号：EP2438989B1

  公开（公告）日：2016-04-13