3,4-dihydroxy-heptan-2-one | 101080-32-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3,4-dihydroxy-heptan-2-one
• 英文别名: 3,4-Dihydroxy-heptan-2-on；3,4-Dihydroxyheptan-2-one
• CAS: 101080-32-4
• 化学式: C₇H₁₄O₃
• 分子量: 146.186
• InChiKey: WMONXLCFDLFZOM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0
• 重原子数：
  10
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  57.5
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  正丁醛 、 羟基丙酮 在 C₃₃H₄₃N₃O₃Si 作用下， 以 5,5-dimethyl-1,3-cyclohexadiene 为溶剂， 生成 (3R,4S)-3,4-dihydroxyheptan-2-one 、 3,4-dihydroxy-heptan-2-one
  参考文献：
  名称：

  羟基丙酮和醛的高效有机催化直接不对称羟醛反应

  摘要：

  合成了衍生自L-苏氨酸和L-亮氨酸的新型有机催化剂，用于催化羟基丙酮与未活化的脂族醛的直接醛醇缩合反应，催化剂的负载量低至2 mol％，对脂族醛具有良好至优异的收率和优异的对映选择性。 ，而芳族醛仅产生中等对映选择性。

  DOI：

  10.1002/adsc.200800558

文献信息

• COMPOUNDS AND METHODS FOR INHIBITING NHE-MEDIATED ANTIPORT IN THE TREATMENT OF DISORDERS ASSOCIATED WITH FLUID RETENTION OR SALT OVERLOAD AND GASTROINTESTINAL TRACT DISORDERS
  申请人：ARDELYX, INC.

  公开号：US20150336892A1

  公开（公告）日：2015-11-26

  The present disclosure is directed to compounds and methods for the treatment of disorders associated with fluid retention or salt overload, such as heart failure (in particular, congestive heart failure), chronic kidney disease, end-stage renal disease, liver disease, and peroxisome proliferator-activated receptor (PPAR) gamma agonist-induced fluid retention. The present disclosure is also directed to compounds and methods for the treatment of hypertension. The present disclosure is also directed to compounds and methods for the treatment of gastrointestinal tract disorders, including the treatment or reduction of pain associated with gastrointestinal tract disorders.

  本公开涉及化合物和方法，用于治疗与液体潴留或盐过量相关的疾病，例如心力衰竭（特别是充血性心力衰竭）、慢性肾脏疾病、晚期肾脏疾病、肝病和过氧化物酶体增殖物激活受体（PPAR）γ激动剂引起的液体潴留。本公开还涉及化合物和方法，用于治疗高血压。本公开还涉及化合物和方法，用于治疗胃肠道疾病，包括治疗或减轻与胃肠道疾病相关的疼痛。
• Heat-ray reflective film, heat-ray reflective structure, and production method thereof
  申请人：FUJIFILM Corporation

  公开号：EP2219053A1

  公开（公告）日：2010-08-18

  A heat-ray reflective films, containing: a convex-concave portion formed by arranging a plurality of concave portions in one surface of the heat-ray reflective film using the surface as a base plane; and a conductive layer formed on a surface of the convex-concave portion, wherein each of the concave portions has a depth of less than 1 µm, and the conductive layer has a thickness of 1 µm or less, and wherein the convex-concave portion contains a slanted side wall, and the heat-ray reflective film satisfies the relationship of: A/B×100≥20% where A denotes a projected area obtained by vertically projecting the slanted side wall of the convex portion onto a horizontal plane, and B denotes a projected area obtained by vertically projecting the entire concave portion onto a horizontal plane.

  一种热射线反射膜，包含：以热射线反射膜的一个表面为基面，在该表面上排列多个凹部而形成的凸凹部；以及形成在凸凹部表面上的导电层，其中每个凹部的深度小于 1 µm，导电层的厚度小于等于 1 µm，凸凹部包含一个斜侧壁，热射线反射膜满足以下关系：A/B×100≥20%，其中 A 表示将凸面部分的斜侧壁垂直投影到水平面上得到的投影面积，B 表示将整个凹面部分垂直投影到水平面上得到的投影面积。
• AZO METAL CHELATE DYE AND OPTICAL RECORDING MEDIUM
  申请人：Mitsubishi Kagaku Media Co., Ltd.

  公开号：EP2302003A1

  公开（公告）日：2011-03-30

  To provide a dye to be used for an optical recording medium excellent in both high speed recording characteristics and reproduction durability. A dye having an azo compound represented by the following formula coordinated to a metal ion: wherein the ring A represents a nitrogen-containing heteroaromatic ring containing a carbon atom and a nitrogen atom; X represents C-R1R2, an oxygen atom, a sulfur atom or N-R3, wherein each of R1, R2 and R3 which are independent of one another, represents a hydrogen atom, a linear or branched alkyl group, an aralkyl group, a cycloalkyl group, a linear or branched alkenyl group, an aryl group or an acyl group represented by -COR4, wherein R4 is a hydrocarbon group or a heterocyclic group which may be substituted; and the benzene ring B represents a benzene ring which may have a substituent(s), provided that adjacent substituents in the benzene ring B may be mutually bonded to form a ring.

  提供一种在高速记录特性和再现耐久性方面都非常出色的用于光学记录介质的染料。 一种染料具有与金属离子配位的下式所代表的偶氮化合物： 其中环 A 代表含有一个碳原子和一个氮原子的含氮杂芳香环；X 代表 C-R1R2、氧原子、硫原子或 N-R3，其中 R1、R2 和 R3 各自相互独立，代表氢原子、直链或支链烷基、芳烷基、环烷基、直链或支链烯基、芳基或由 -COR4 代表的酰基，其中 R4 是烃基或可被取代的杂环基；苯环 B 代表可具有取代基的苯环，条件是苯环 B 中的相邻取代基可相互结合形成环。
• OPTICAL INFORMATION RECORDING MEDIUM, METHOD FOR INFORMATION RECORDING, AND AZO METAL COMPLEX DYE
  申请人：FUJIFILM Corporation

  公开号：EP2351650A1

  公开（公告）日：2011-08-03

  An aspect of the present invention relates to an optical information recording medium comprising a recording layer on a surface of a support, wherein the surface of the support has pregrooves with a track pitch ranging from 50 to 500 nm, the recording layer comprises an azo metal complex dye being a complex of six azo dyes and seven transition metal ions. A further aspect of the present invention relates to a method of recording information onto the optical information recording medium and a novel azo metal complex dye.

  本发明的一个方面涉及一种光学信息记录介质，该介质包括位于支撑物表面上的记录层，其中支撑物表面具有轨距为50至500纳米的预槽，记录层包括偶氮金属络合染料，该染料是六种偶氮染料和七种过渡金属离子的复合物。本发明的另一方面涉及将信息记录到光学信息记录介质和新型偶氮金属络合染料上的方法。
• Compound which performs non-resonant two-photon absorption, non-resonant two-photon light-emitting compound and non-resonant two-photon absorption induction method and process for emitting light thereby, optical data recording medium and process for recording data thereon, and two-photon polymerizable composition and process for polymerization thereof
  申请人：FUJI PHOTO FILM CO., LTD.

  公开号：US20030162124A1

  公开（公告）日：2003-08-28

  The present invention provides a two-photon light-emitting compound represented by formula (1), an optical data recording medium capable of recording data with a laser beam comprising a compound represented by formula (1) and a two-photon polymerizable composition photopolymerizable by two-photon absorption comprising a polymerizable monomer or polymerizable oligomer and at least a two-photon absorption material being a compound represented by formula (1): X 2 —(—CR 4 ═CR 3 —) m —C(═O)—(—CR 1 ═CR 2 —) n —X 1 (1) wherein X 1 and X 2 may be the same or different and each represent a substituted or unsubstituted aryl group or a substituted or unsubstituted heterocyclic group; R 1 , R 2 , R 3 and R 4 each independently represent a hydrogen atom or substituent; some of R 1 , R 2 , R 3 and R 4 may be connected to each other to form at least one ring; and n and m each independently represent an integer of from 1 to 4, with the proviso that when n and m are 2 or more, the plurality of R 1 's, R 2 's, R 3 's, and R 4 's each may be the same or different. The present invention also provides a photopolymerization process which causes polymerization reaction utilizing two-photon or higher multiple photon absorption induced by irradiating the above polymerizable composition with laser beam having a wavelength longer than the linear absorption band of the compound of the formula (1) and free of linear absorption.

  本发明提供了一种由式（1）表示的双光子发光化合物、一种能够用激光束记录数据的光学数据记录介质，该介质由式（1）表示的化合物和一种可通过双光子吸收进行光聚合的双光子可聚合组合物组成，该组合物由可聚合单体或可聚合低聚物和至少一种双光子吸收材料（即式（1）表示的化合物）组成： X 2 -(-CR 4 ═CR 3 -) m -C(═O)-(-CR 1 ═CR 2 -) n -X 1 (1) 其中 X 1 和 X 2 可以相同或不同，各自代表取代或未取代的芳基或取代或未取代的杂环基团； R 1 , R 2 , R 3 和 R 4 各自独立地代表一个氢原子或取代基；R 1 , R 2 , R 3 和 R 4 可相互连接形成至少一个环；n 和 m 各自独立地代表 1 至 4 的整数，但当 n 和 m 为 2 或更多时，多个 R 1 、R 2 、R 3 和 R 4 可以相同，也可以不同。本发明还提供了一种光聚合工艺，利用波长长于式（1）化合物线性吸收带且无线性吸收的激光束照射上述可聚合组合物，诱导双光子或更高的多重光子吸收，从而引起聚合反应。