13β-hydroxyazorellane

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 13β-hydroxyazorellane
• 英文别名: Mulinane diterpenoid；(1R,2R,5R,6R,9S,12S,13R)-6,9,12-trimethyl-5-propan-2-yltetracyclo[7.5.0.01,13.02,6]tetradecan-12-ol
• 化学式: C₂₀H₃₄O
• 分子量: 290.489
• InChiKey: LIXXTIXZQFXCDM-KSLKBLKXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  21
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  13β-hydroxyazorellane 在 对甲苯磺酸 作用下， 以 苯 为溶剂， 反应 1.0h， 以23 mg的产率得到(3R,3aR,5aR)-3-Isopropyl-3a,5a,8-trimethyl-1,2,3,3a,4,5,5a,6,7,10-decahydro-cyclohepta[e]indene
  参考文献：
  名称：

  Diterpenoids from Azorella yareta and their trichomonicidal activities

  摘要：

  Diterpenoids with trichomonicidal activity were isolated from the aerial parts of Azorella yareta Hauman. One was 13 beta -hydroxy-azorellane, together with the known constituents mulinolic acid, mulin-11,13-dien-20-oic acid, azorellanol and 13 alpha -hydroxyazorellane. Their structures were determined by spectroscopic and chemical methods. (C) 2001 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0031-9422(00)00380-0

文献信息

• Diterpenoids from Azorella yareta and their trichomonicidal activities
  作者：Luis A Loyola、Jorge Bórquez、Glauco Morales、Jorge Araya、Jorge González、Ivan Neira、Hernan Sagua、Aurelio San-Martı́n

  DOI：10.1016/s0031-9422(00)00380-0

  日期：2001.1

  Diterpenoids with trichomonicidal activity were isolated from the aerial parts of Azorella yareta Hauman. One was 13 beta -hydroxy-azorellane, together with the known constituents mulinolic acid, mulin-11,13-dien-20-oic acid, azorellanol and 13 alpha -hydroxyazorellane. Their structures were determined by spectroscopic and chemical methods. (C) 2001 Elsevier Science Ltd. All rights reserved.

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