肼,[(4-苯氧基苯基)甲基]- | 91280-39-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 肼,[(4-苯氧基苯基)甲基]-
• 英文名称: 10-Methyl-1-decalon
• 英文别名: 9-Methyl-dacalon-1；9-Methyl-1-decalon；10-Methyl-decalon；1(2H)-Naphthalenone, octahydro-8a-methyl-, cis-；8a-methyl-2,3,4,4a,5,6,7,8-octahydronaphthalen-1-one
• CAS: 91280-39-6
• 化学式: C₁₁H₁₈O
• mdl: MFCD00598450
• 分子量: 166.263
• InChiKey: DEOBYOFNFVUIGX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.909
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  肼,[(4-苯氧基苯基)甲基]- 在 正丁基锂 、 potassium tert-butylate 作用下， 以 四氢呋喃 、 正己烷 、 苯 为溶剂， 反应 5.0h， 生成 1-(1,3-dithian-2-yl)-8a-methylspiro[4,4a,5,6,7,8-hexahydro-3H-naphthalene-2,1'-cyclopentane]-1-ol
  参考文献：
  名称：

  A New Redundant Rearrangement of Aromatic Ring Fused Cyclic α-Hydroxydithiane Derivatives. Synthesis of Aromatic Ring Fused Cyclic 1,2-Diketones with One-Carbon Ring Expansion

  摘要：

  A new reaction involving rearrangement of aromatic ring fused cyclic dithiane alcohol by N-chlorosuccinimide in CH2Cl2-H2O to the corresponding one-carbon ring expanded 1,2-diketone has been developed. A wide range of structurally varied dithiane alcohols have been found to undergo this rearrangement in high yields. The general criteria and reaction mechanism for this rearrangement have also been worked out.

  DOI：

  10.1021/jo990634s
• 作为产物：
  描述：

  9-phenylthiomethyl-1-decalone 在 镍 作用下， 生成 肼,[(4-苯氧基苯基)甲基]-
  参考文献：
  名称：

  Regiospecific α-methylenation and α-methylation of ketones: titanium tetrachloride promoted phenylthiomethylation of silyl enol ethers

  摘要：

  DOI：

  10.1016/s0040-4039(01)86072-x

文献信息

• Campbell; Petragnani; Brocksom, Farmaco, Edizione Scientifica, 1978, vol. 33, # 6, p. 421 - 433
  作者：Campbell、Petragnani、Brocksom、Tsuchiya

  DOI：——

  日期：——
• PATERSON, IAN, TETRAHEDRON, 44,(1988) N 13, 4207-4219
  作者：PATERSON, IAN

  DOI：——

  日期：——
• Regiospecific α-methylenation and α-methylation of ketones: titanium tetrachloride promoted phenylthiomethylation of silyl enol ethers
  作者：Ian Peterson、Ian Fleming

  DOI：10.1016/s0040-4039(01)86072-x

  日期：1979.1
• A New Redundant Rearrangement of Aromatic Ring Fused Cyclic α-Hydroxydithiane Derivatives. Synthesis of Aromatic Ring Fused Cyclic 1,2-Diketones with One-Carbon Ring Expansion
  作者：Brindaban C. Ranu、Umasish Jana

  DOI：10.1021/jo990634s

  日期：1999.8.1

  A new reaction involving rearrangement of aromatic ring fused cyclic dithiane alcohol by N-chlorosuccinimide in CH2Cl2-H2O to the corresponding one-carbon ring expanded 1,2-diketone has been developed. A wide range of structurally varied dithiane alcohols have been found to undergo this rearrangement in high yields. The general criteria and reaction mechanism for this rearrangement have also been worked out.