1-tert.-Butyl-cycloocten-(1) | 53723-39-0

• 分子结构分类: 有机化合物 - 碳氢化合物 - 不饱和烃
• 英文名称: 1-tert.-Butyl-cycloocten-(1)
• 英文别名: (1E)-1-tert-butylcyclooctene
• CAS: 53723-39-0
• 化学式: C₁₂H₂₂
• 分子量: 166.307
• InChiKey: YAEDRVJWOGAOFS-PKNBQFBNSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  1-tert.-Butyl-cycloocten-(1) 在 sodium hydroxide 、 双氧水 、 diborane(6) 作用下， 反应 10.0h， 生成 1-tert-butylcyclooctanol
  参考文献：
  名称：

  Complete retention in substitution and stereospecificity in transannular reactions of cis- and trans-3-tert-butylcyclooctyl tosylates

  摘要：

  DOI：

  10.1021/ja00402a040
• 作为产物：
  描述：

  1-tert-butyl-1,2-cyclooctadiene 在 palladium on activated charcoal 氢气 作用下， 生成 1-tert.-Butyl-cycloocten-(1)
  参考文献：
  名称：

  小环环状枯草烯：动力学稳定的八元环亚丙基的合成

  摘要：

  从环庚酮分四步制备1-叔丁基-1，2-环戊二烯，发现对二聚反应稳定。

  DOI：

  10.1016/s0040-4039(00)85036-4

文献信息

• Conformational analysis. LXII. solvolysis and deamination studies of the 5-t-butylcylooctyl system.
  作者：N.L. Allinger、W. Szkrybalo

  DOI：10.1016/s0040-4020(01)98666-1

  日期：1968.1

  The solvolyses of cis- and trans-5-t-butylcyclooctyl tosylates in acetic acid have been studied, and the rates and products are reported. The fast rate and rearranged product from the cis isomer are interpreted in terms of neighboring group participation by hydride. Improved syntheses of the compounds are given. Deamination reactions of the corresponding amines were also studied, and a product study

  的solvolyses顺-和反式醋酸-5叔butylcyclooctyl苯磺酸进行了研究，并率和产品的报道。顺式异构体的快速生成和重排产物是通过氢化物的邻近基团参与来解释的。给出了化合物的改进的合成。还研究了相应胺的脱氨基反应，并根据公认的反应机理描述和解释了产物研究。
• The addition of alkyllithium reagents to trans-cyclooctene. The facile elimination of lithium hydride in the cyclooctyl ring
  作者：Robert D. Bach、Kenneth W. Bair、Carl L. Willis

  DOI：10.1016/s0022-328x(00)89417-6

  日期：1974.9

  The addition of s-butyllithium and t-butyllithium to trans-cyclooctene has been shown to occur very readily. The facile elimination of lithium hydride from s-cyclooctyllithium compounds affording cyclooctenes is also reported.

  已显示非常容易地将仲丁基锂和叔丁基锂加到反式环辛烯中。还报道了从提供环辛烯的s-环辛基锂化合物中容易地除去氢化锂。
• η³-Allylpalladium Complexes from Medium-Ring Cycloalkenes
  作者：Jean-Marie Rosset、Matthew P. Glenn、John D. Cotton、Anthony C. Willis、Colin H. L. Kennard、Karl A. Byriel、Bruce H. Riches、William Kitching

  DOI：10.1021/om971132c

  日期：1998.5.1

  The dimeric eta(3)-allylpalladium chloride complexes formed from various cycloalkenes (C-7-C-13) and some methyl-and tert-butyl-substituted cycle alkenes have be en characterized by H-1 and C-13 NMR spectroscopy and in selected cases by X-ray crystallography. The formation of syn and anti isomers in the larger ring systems is demonstrated, and complexes with a rearranged ring system are formed from tert-butylcyclodecene and tert-butylcyclododecene. The sesquiterpene, carophyllene, is shown to form an eta(3)-allyl exocyclic complex, exclusively from the (E)-double bond. Cis and trans isomers, with respect to allyl group orientation in these halo-bridged dimers, have been identified by low-temperature (190K) NMR spectroscopy, and their interconversion (Delta G(double dagger) approximate to 11 kcal/mol) is considered to involve a "cubic" eta(3)-allylpalladium chloride tetramer.
• Regioselective Formation of Cyclic and Allylic Hydroperoxides
  作者：Manolis Stratakis、Michael Orfanopoulos

  DOI：10.1080/00397919308009797

  日期：1993.2

  A regioselective photosensitized oxygenation is reported for the preparation of cyclic and allylic hydroperoxides.
• SCHNEIDER H.-J.; HEISKE D., J. AMER. CHEM. SOC., 1981, 103, NO 12, 3501-3505
  作者：SCHNEIDER H.-J.、 HEISKE D.

  DOI：——

  日期：——