6-双环[2.2.1]庚基乙酸酯 | 34640-76-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 中文名称: 6-双环[2.2.1]庚基乙酸酯
• 英文名称: 2-Norbonylacetat
• 英文别名: endo-norbornyl acetate；exo-norbornyl acetate；exo-2-norbornyl acetate；norborneol acetate；2-Acetoxymethyl-bicyclo<2.2.1>heptan；2-Acetoxybicyclo<2.2.1>heptan；2-Acetoxynorbornan (exo)；norbornyl acetate；2-bicyclo[2.2.1]heptanyl acetate
• CAS: 34640-76-1
• 化学式: C₉H₁₄O₂
• 分子量: 154.209
• InChiKey: YXNICIBZSREEPY-UHFFFAOYSA-N

物化性质

• LogP：
  2.319 (est)
• 保留指数：
  1114;1114.3;1112;1112

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.888
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 海关编码：
  2915390090

SDS

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Section 1. IDENTIFICATION OF THE SUBSTANCE/MIXTURE
Product identifiers
Product name : 2-Norbornyl acetate
CAS-No. : 34640-76-1
Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances

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Section 2. HAZARDS IDENTIFICATION
Classification of the substance or mixture
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.
Label elements
Caution - substance not yet tested completely.
Other hazards - none

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Section 3. COMPOSITION/INFORMATION ON INGREDIENTS
Substances
Synonyms : bicyclo[2.2.1]hept-2-yl acetate
Formula : C9H14O2
Molecular Weight : 154,21 g/mol

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Section 4. FIRST AID MEASURES
Description of first aid measures
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration.
In case of skin contact
Wash off with soap and plenty of water.
In case of eye contact
Flush eyes with water as a precaution.
If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water.
Most important symptoms and effects, both acute and delayed
To the best of our knowledge, the chemical, physical, and toxicological properties have not been
thoroughly investigated.
Indication of any immediate medical attention and special treatment needed
no data available

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Section 5. FIREFIGHTING MEASURES
Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides
Advice for firefighters
Wear self contained breathing apparatus for fire fighting if necessary.
Further information
no data available

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Section 6. ACCIDENTAL RELEASE MEASURES
Personal precautions, protective equipment and emergency procedures
Avoid breathing vapors, mist or gas.
Environmental precautions
Do not let product enter drains.
Methods and materials for containment and cleaning up
Keep in suitable, closed containers for disposal.
Reference to other sections
For disposal see section 13.

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Section 7. HANDLING AND STORAGE
Precautions for safe handling
Normal measures for preventive fire protection.
Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are
opened must be carefully resealed and kept upright to prevent leakage.
Specific end uses
no data available

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Section 8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Control parameters
Components with workplace control parameters
Exposure controls
Appropriate engineering controls
General industrial hygiene practice.
Personal protective equipment
Eye/face protection
Use equipment for eye protection tested and approved under appropriate government standards
such as NIOSH (US) or EN 166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
(without touching glove's outer surface) to avoid skin contact with this product. Dispose of
contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.
The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and
the standard EN 374 derived from it.
Body Protection
impervious clothing, The type of protective equipment must be selected according to the
concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection
Respiratory protection not required. For nuisance exposures use type OV/AG (US) or type ABEK
(EU EN 14387) respirator cartridges. Use respirators and components tested and approved under
appropriate government standards such as NIOSH (US) or CEN (EU).

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Section 9. PHYSICAL AND CHEMICAL PROPERTIES
Information on basic physical and chemical properties
a) Appearance Form: liquid
b) Odour no data available
c) Odour Threshold no data available
d) pH no data available
e) Melting point/freezing no data available
point
f) Initial boiling point and no data available
boiling range
g) Flash point no data available
h) Evaporation rate no data available
i) Flammability (solid, gas) no data available
j) Upper/lower no data available
flammability or
explosive limits
k) Vapour pressure no data available
l) Vapour density no data available
m) Relative density no data available
n) Water solubility no data available
o) Partition coefficient: n- no data available
octanol/water
p) Autoignition no data available
temperature
q) Decomposition no data available
temperature
r) Viscosity no data available
s) Explosive properties no data available
t) Oxidizing properties no data available
Other safety information
no data available

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Section 10. STABILITY AND REACTIVITY
Reactivity
no data available
Chemical stability
no data available
Possibility of hazardous reactions
no data available
Conditions to avoid
no data available
Incompatible materials
Strong oxidizing agents
Hazardous decomposition products
Other decomposition products - no data available

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Section 11. TOXICOLOGICAL INFORMATION
Information on toxicological effects
Acute toxicity
no data available
Skin corrosion/irritation
no data available
Serious eye damage/eye irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as
probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
no data available
Specific target organ toxicity - single exposure
no data available
Specific target organ toxicity - repeated exposure
no data available
Aspiration hazard
no data available
Potential health effects
Inhalation
May be harmful if inhaled. May cause respiratory tract irritation.
Ingestion May be harmful if swallowed.
Skin May be harmful if absorbed through skin. May cause skin irritation.
Eyes May cause eye irritation.
Signs and Symptoms of Exposure
To the best of our knowledge, the chemical, physical, and toxicological properties have not been
thoroughly investigated.
Additional Information
RTECS: Not available

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Section 12. ECOLOGICAL INFORMATION
Toxicity
no data available
Persistence and degradability
no data available
Bioaccumulative potential
no data available
Mobility in soil
no data available
Results of PBT and vPvB assessment
no data available
Other adverse effects
no data available

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Section 13. DISPOSAL CONSIDERATIONS
Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contaminated packaging
Dispose of as unused product.

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Section 14. TRANSPORT INFORMATION
UN number
ADR/RID: - IMDG: - IATA: -
UN proper shipping name
ADR/RID: Not dangerous goods
IMDG: Not dangerous goods
IATA: Not dangerous goods
Transport hazard class(es)
ADR/RID: - IMDG: - IATA: -
Packaging group
ADR/RID: - IMDG: - IATA: -
Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
Special precautions for user
no data available

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SECTION 15 - REGULATORY INFORMATION
N/A

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SECTION 16 - ADDITIONAL INFORMATION
N/A

反应信息

• 作为反应物：
  描述：

  6-双环[2.2.1]庚基乙酸酯 在 甲醇 、 水 、 potassium hydroxide 作用下， 反应 1.5h， 以105.5 g的产率得到双环[2.2.1]-2-庚醇
  参考文献：
  名称：

  一种带桥环结构（甲基）丙烯酸酯的制备方法

  摘要：

  本发明涉及一种带桥环结构（甲基）丙烯酸酯的制备方法，通过三步反应合成，首先利用饱和脂肪酸与桥环烯烃或其衍生物进行直接加成，精馏提纯，去除桥环烯烃自聚产生的副产物；然后进行水解，得到对应的桥环醇或其衍生物；最后利用（甲基）丙烯酸甲酯与之进行酯交换反应得到带桥环结构（甲基）丙烯酸酯。本发明制备方法简单，步骤易于操作，通过三步反应得到目标产物且收率高，克服了直接酯化工艺精馏过程要求高、收率低的缺点，产品残留环烯烃单体含量低，应用于树脂合成时，可明显改善树脂黄变以及粘度增加的缺点。

  公开号：

  CN108299194A
• 作为产物：
  描述：

  2-Acetoxy-2-norbornylquecksilberchlorid 在 sodium tetrahydroborate 作用下， 以 二氯甲烷 、 水 为溶剂， 反应 0.5h， 以83%的产率得到6-双环[2.2.1]庚基乙酸酯
  参考文献：
  名称：

  Giese, Bernd; Erfort, Ulrich, Chemische Berichte, 1983, vol. 116, # 3, p. 1240 - 1251

  摘要：

  DOI：

文献信息

• Aluminium dodecatungstophosphate (AlPW12O40) as a highly efficient catalyst for the selective acetylation of –OH, –SH and –NH2 functional groups in the absence of solvent at room temperature
  作者：Habib Firouzabadi、Nasser Iranpoor、Farhad Nowrouzi、Kamal Amani

  DOI：10.1039/b300775h

  日期：2003.3.6

  AlPW12O40 was found to be an effective catalyst for the selective acetylation of alcohols, thiols, and amines in the absence of solvent at room temperature.

  AlPW12O40被发现是一种有效的催化剂，可在室温无溶剂条件下选择性乙酰化醇、硫醇和胺。
• Consecutive addition esterification and hydrolysis of cyclic olefins catalyzed by multi-SO₃H functionalized multi heteropolyanion-based ionic hybrids undersolvent-free conditions
  作者：Guocai Zheng、Xinzhong Li

  DOI：10.1080/00397911.2019.1580743

  日期：2019.4.3

  for the synthesis of cycloalkyl carboxylates and alcohols from cyclic olefins is described. The cyclic olefins were converted to corresponding target molecules under solvent-free conditions catalyzed by two novel multi-SO3H functionalized multi heteropolyanion-based ionic hybrids through one-pot consecutive addition esterification and hydrolysis reactions. This approach has several advantages, including

  摘要 描述了从环烯烃合成环烷基羧酸盐和醇的有效方案。环烯烃在无溶剂条件下通过一锅连续加成酯化和水解反应由两种新型多 SO3H 官能化多杂多阴离子基离子杂化物催化转化为相应的目标分子。这种方法有几个优点，包括高产率、简单的后处理和简单的纯化。图形概要
• Fluorine-Containing Sulfonic Acid Salt, Fluorine-Containing Sulfonic Acid Salt Resin, Resist Composition, and Pattern Forming Method Using Same
  申请人：Central Glass Company, Limited

  公开号：US20150198879A1

  公开（公告）日：2015-07-16

  Disclosed is a fluorine-containing sulfonic acid salt resin having a repeating unit represented by the following general formula (3). In the formula, each A independently represents a hydrogen atom, a fluorine atom or a trifluoromethyl group, and n represents an integer of 1-10. W represents a bivalent linking group, R 01 represents a hydrogen atom or a monovalent organic group, and M + represents a monovalent cation. A resist composition containing this resin is further superior in sensitivity, resolution and reproducibility of mask pattern and is capable of forming a pattern with a low LER.

  本公开了一种含氟磺酸盐树脂，其具有以下通用式（3）所代表的重复单元。在该式中，每个A独立地表示氢原子、氟原子或三氟甲基基团，n表示1-10的整数。W表示二价连接基团，R01表示氢原子或一价有机基团，M+表示一价阳离子。含有该树脂的抗蚀组合物在感光性、分辨率和掩膜图案的重现性方面更加优越，并且能够形成具有较低LER的图案。
• Reaction of Organoboranes with Lead(IV) Acetate Azide. A Synthesis of Azidoalkanes from Alkenes<i>via</i>Hydroboration
  作者：Yuzuru Masuda、Masayuki Hoshi、Akira Arase

  DOI：10.1246/bcsj.57.1026

  日期：1984.4

  Trialkylboranes prepared from alkenes via hydroboration react with lead(IV) acetate azide in dichloromethane at −25 °C to form the corresponding azidoalkanes in a one-pot manner. One or two of the alkyl groups of trialkylboranes are utilized in the reaction. For example, 1-azidohexane is afforded from 1-hexene in 50% yield based on the alkene employed.

  由烯烃通过硼氢化反应制备的三烷基硼烷与醋酸铅（IV）叠氮化物在二氯甲烷中在 -25°C 下以一锅法反应形成相应的叠氮烷烃。反应中使用了三烷基硼烷的一个或两个烷基。例如，基于所使用的烯烃，1-叠氮己烷以50%的产率由1-己烯提供。
• The novel synthesis of alkyl cyanides by the reaction of sodium trialkylcyanoborate with sodium cyanide and lead(IV) acetate
  作者：Yuzuru Masuda、Masayuki Hoshi、Tetsuo Yamada、Akira Arase

  DOI：10.1039/c39840000398

  日期：——

  Sodium trialkylcyanoborates gave good yields to the corresponding alkyl cyanides in the reactions with sodium cyanide and lead(IV) acetate.

  在氰化钠和乙酸铅（IV）的反应中，三烷基氰基硼酸钠对相应的烷基氰化物具有良好的收率。

表征谱图