2-methyl-1-[4-piperazinophenyl]-2-morpholinopropan-1-one | 886463-09-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-methyl-1-[4-piperazinophenyl]-2-morpholinopropan-1-one
• 英文别名: 2-methyl-2-morpholin-4-yl-1-(4-piperazinylphenyl)propan-1-one；2-Methyl-1-[4-piperazinophenyl]-2-morpholino propan-1-one；2-methyl-2-morpholin-4-yl-1-(4-piperazin-1-ylphenyl)propan-1-one
• CAS: 886463-09-8
• 化学式: C₁₈H₂₇N₃O₂
• 分子量: 317.431
• InChiKey: GYHTWUIMDHGUGQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.61
• 拓扑面积：
  44.8
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  2-methyl-1-[4-piperazinophenyl]-2-morpholinopropan-1-one 、 二乙二醇双氯甲酸酯 在 三乙胺 作用下， 以 甲苯 为溶剂， 反应 2.0h， 生成 2-[2-[4-[4-(2-Methyl-2-morpholin-4-ylpropanoyl)phenyl]piperazine-1-carbonyl]oxyethoxy]ethyl 4-[4-(2-methyl-2-morpholin-4-ylpropanoyl)phenyl]piperazine-1-carboxylate
  参考文献：
  名称：

  WO2006/82477

  摘要：

  公开号：
• 作为产物：
  描述：

  2-(4-chloro-phenyl)-2-methoxy-3,3-dimethyl-oxirane 在 palladium diacetate 、 2-(二叔丁基膦)联苯 potassium tert-butylate 作用下， 以 四氢呋喃 、 甲苯 为溶剂， 反应 68.0h， 生成 2-methyl-1-[4-piperazinophenyl]-2-morpholinopropan-1-one
  参考文献：
  名称：

  MICHAEL ADDITION REACTION PRODUCT AND ACTIVE ENERGY RAY-CURABLE COMPOSITION

  摘要：

  公开号：

  EP2450344B1

文献信息

• Piperazino Based Photoinitiators
  申请人：Herlihy Lawrence Shaun

  公开号：US20080045620A1

  公开（公告）日：2008-02-21

  Compounds of formula (I): [where: the substituents R 1 are individually selected from C 1 -C 10 alkyl groups and optionally substituted benzyl groups; the substituents R 2 are individually selected from alkyl groups or, together with the nitrogen atom to which they are attached, represent a nitrogen-containing heterocyclic group; Z is selected from C 6 -C 10 arylene groups groups of formula —(CHR 3 ) n —, where R 3 is hydrogen, hydroxy or a C 1 -C 4 alkyl group, and n is 0 to 6; Y is carbonyl or a residue of a mono- or poly-hydroxy compound; and x is 1 to 6; and esters thereof] are useful as multi-functional photoinitiators for use in coating compositions to be cured by radiant energy.

  公式（I）的化合物：[其中：取代基R1分别选自C1-C10烷基和可选取代苯基；取代基R2分别选自烷基或与它们连接的氮原子一起表示含氮杂环基团；Z选自C6-C10芳基烷基团的公式-（CHR3）n-，其中R3为氢，羟基或C1-C4烷基，n为0到6；Y为羰基或单或多羟基化合物的残基；x为1到6；以及它们的酯]在由辐射能固化的涂料组合物中作为多功能光引发剂是有用的。
• Piperazino based photoinitiators
  申请人：Sun Chemical Corporation

  公开号：US07612122B2

  公开（公告）日：2009-11-03

  Compounds of formula (I): [where: the substituents R1 are individually selected from C1-C10 alkyl groups and optionally substituted benzyl groups; the substituents R2 are individually selected from alkyl groups or, together with the nitrogen atom to which they are attached, represent a nitrogen-containing heterocyclic group; Z is selected from C6-C10 arylene groups and groups of formula —(CHR3)n—, where R3 is hydrogen, hydroxy or a C1-C4 alkyl group, and n is 0 to 6; Y is carbonyl or —CH2—; Q is a residue of a mono- or poly-hydroxy compound; and x is 1 to 6; and esters thereof] are useful as multi-functional photoinitiators for use in coating compositions to be cured by radiant energy.

  化合物的化学式为（I）：[其中：取代基R1分别选自C1-C10烷基和可选取代苯基基团；取代基R2分别选自烷基或与它们连接的氮原子一起表示含氮杂环基团；Z选自C6-C10芳基基团和公式—（CHR3）n—的基团，其中R3是氢、羟基或C1-C4烷基基团，n为0到6；Y为羰基或—CH2—；Q为单或多羟基化合物的残基；x为1到6；以及它们的酯]，用作多功能光引发剂，用于通过辐射能固化的涂料组合物中。
• Michael addition reaction product and active energy ray-curable composition
  申请人：Fabian Kutzner

  公开号：US08674089B2

  公开（公告）日：2014-03-18

  The present invention provides a Michael addition reaction product between a specified compound having a group which functions as a Michael donor and a monomer or polymer having a group which functions as a Michael acceptor, a photoinitiator containing the Michael addition reaction product, and an active energy ray-curable composition containing the photoinitiator. The compound having a group functioning as a Michael donor used in the present invention is a phenyl ketone derivative and is characterized by having an amino group or a mercapto group as the group functioning as a Michael donor.

  本发明提供了一种迈克尔加成反应产物，该产物是由具有作为迈克尔供体的基团的指定化合物和具有作为迈克尔受体的基团的单体或聚合物之间的反应产生的，还包括含有该迈克尔加成反应产物的光引发剂以及含有该光引发剂的活性能量射线可固化组合物。本发明中使用的具有作为迈克尔供体的基团的化合物是苯基酮衍生物，其特征在于其作为迈克尔供体的基团具有氨基或巯基。
• PIPERAZINO BASED PHOTOINITIATORS
  申请人：Sun Chemical Limited

  公开号：EP1812414B1

  公开（公告）日：2012-12-26
• COMPOUND, ACTIVE ENERGY RAY CURABLE COMPOSITION, CURED ARTICLE THEREOF, PRINTING INK, AND INKJET RECORDING INK
  申请人：DIC Corporation

  公开号：US20170152391A1

  公开（公告）日：2017-06-01

  A compound obtained through Michael addition reaction of an α-aminoacetophenone skeleton-containing compound (I) represented by the following general formula (1) and a reactive compound (II) having a function as a Michael acceptor is used as a photopolymerization initiator. In the general formula (1), R 1 represents an aliphatic group, R 2 to R 3 each independently represent an aliphatic group, etc., R 4 to R 7 each independently represent a hydrogen atom, X 1 represents a single bond or a C1-6 alkylene group, X 2 represents a carbonyl group, Y 1 and Y 2 represent a group represented by the following general formula (2). However, when Y 1 and Y 2 both have a structure represented by the general formula (2), X 5 in at least one of them is —NH—. In the general formula (2), X 3 and X 4 each independently represent a linear or branched alkylene group having 2 to 6 carbon atoms, X 5 represents a single bond, —O— or —NH—.