diosmetin 7-O-glucoside | 20126-59-4

• 物质功能分类: 生物化工 - 提取物 - 植物提取物
• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: diosmetin 7-O-glucoside
• 英文别名: Hesperetin7-O-glucoside；5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-[(3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one
• CAS: 20126-59-4
• 化学式: C₂₂H₂₂O₁₁
• 分子量: 462.41
• InChiKey: WKUHPOMCLBLCOV-JQQDRUSQSA-N

物化性质

• 熔点：
  253-255℃
• 沸点：
  803.6±65.0 °C(Predicted)
• 密度：
  1.609
• 溶解度：
  溶于氯仿、二氯甲烷、乙酸乙酯、DMSO、丙酮等。

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  33
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.32
• 拓扑面积：
  175
• 氢给体数：
  6
• 氢受体数：
  11

安全信息

• 危险性防范说明：
  P264,P270,P301+P312,P330,P501
• 危险性描述：
  H302

制备方法与用途

生物活性 Diosmetin-7-O-β-D-glucopyranoside 是从菊花中提取的一种天然产物，具有抗氧化活性。

化学性质 这是一种黄色粉末，可溶于甲醇、乙醇和DMSO等有机溶剂。它来源于柠檬、香叶树皮以及菊花。

用途 该物质适用于含量测定、鉴定及药理实验等。

文献信息

• ANTIOXIDANT MATERIAL, ANTI-DETERIORATION AGENT AND FOOD OR BEVERAGE
  申请人：POKKA CORPORATION

  公开号：EP1783193A1

  公开（公告）日：2007-05-09

  An antioxidant material of the present invention contains flavonoid aglycon and vitamin C. The flavonoid aglycon is eriodictyol and/or diosmetin obtained by treatment of a raw material containing flavonoid glycoside derived from lemons, limes, or sudachis to form the aglycones thereof. It is preferred that this antioxidant material be produced through a step of mixing the flavonoid aglycon and the vitamin C after the treatment to form the aglycones. The treatment to form the aglycones is glycosidase treatment using a β-glycosidase derived from a microorganism of the genus Aspergillus or Penicillium multicolor, or microbial fermentative treatment using a microorganism of the genus Aspergillus. An anti-deterioration agent and a food or beverage of the present invention contain the antioxidant material.

  本发明的一种抗氧化剂材料含有黄酮苷元和维生素 C。黄酮苷元是通过处理从柠檬、酸橙或苏打树提取的含有黄酮苷元的原料以形成其苷元而获得的二碘酪醇（eriodictyol）和/或二锇醇（diosmetin）。这种抗氧化剂材料最好是在处理形成苷元后，通过将黄酮苷元和维生素 C 混合的步骤生产出来。形成苷元的处理方法是使用从曲霉属或多色青霉属微生物中提取的β-糖苷酶进行糖苷酶处理，或使用曲霉属微生物进行微生物发酵处理。本发明的抗变质剂和食品或饮料含有抗氧化材料。
• Beverage composition and method of preventing degradation of vitamins in beverages
  申请人：PepsiCo, Inc.

  公开号：EP1782701A1

  公开（公告）日：2007-05-09

  A vitamin fortified composition comprising vitamin stabilizers which are C6-C3 phenylpropenoic carbonyl compounds to prevent the degradation of the vitamins is provided. In addition, a method of preventing the degradation of vitamins in a vitamin fortified composition is provided.

  本发明提供了一种维生素强化组合物，其中包含维生素稳定剂（C6-C3 苯丙烯酰羰基化合物），以防止维生素降解。此外，还提供了一种防止维生素强化组合物中维生素降解的方法。
• Beverage composition and method of reducing degradation of monatin
  申请人：PepsiCo, Inc.

  公开号：EP2543264A1

  公开（公告）日：2013-01-09

  A beverage comprising a first ingredient which comprises a C6-C3 phenylpropenoic carbonyl compound in an effective amount to reduce degradation of a second ingredient in the beverage, the second ingredient being monatin, and to reduce a corresponding change in a characteristic of the beverage. In addition, a method of preventing the degradation of monatin in a monatin-containing composition is provided.

  一种饮料，其第一成分包含 C6-C3 苯丙烯羰基化合物，其有效含量可减少饮料中第二成分的降解，第二成分为莫纳汀，并减少饮料特性的相应变化。此外，还提供了一种防止含莫纳汀成分中莫纳汀降解的方法。
• METHOD FOR PRODUCING FLAVONOID CLATHRATE
  申请人：Taiyo Kagaku Co., Ltd.

  公开号：EP3453766A1

  公开（公告）日：2019-03-13

  A method for producing a flavonoid inclusion compound, including a cleaving step including treating a sparingly soluble flavonoid having a rhamnoside structure with an enzyme having a rhamnosidase activity in the presence of a cyclodextrin to cleave a rhamnose. According to the production method of the present invention, a flavonoid inclusion compound and a composition of flavonoid glycosides having excellent solubility in water can be efficiently produced, so that the compound and composition can be suitably utilized in the fields of medicaments, foodstuff, health foods, foods for specified health use, cosmetics, and the like.

  一种生产类黄酮包合物的方法，包括裂解步骤，该步骤包括在环糊精存在下，用具有鼠李糖酶活性的酶处理具有鼠李糖苷结构的稀溶性类黄酮，以裂解鼠李糖。根据本发明的生产方法，可以有效地生产出在水中具有良好溶解性的黄酮类包合物和黄酮苷组合物，从而可以将该化合物和组合物适当地用于药物、食品、保健食品、特定保健用食品、化妆品等领域。
• FLAVONOID INCLUSION COMPOUNDS
  申请人：Taiyo Kagaku Co., Ltd.

  公开号：EP3733860A1

  公开（公告）日：2020-11-04

  The present invention comprises a flavonoid inclusion compound which is an inclusion compound of a flavonoid without rhamnoside structure and a cyclic oligosaccharide selected from cyclodextrin, cyclodextran, cyclofructan, cycloalteman, and cluster dextrin, wherein the flavonoid portion has a solubility in water of 2% or more at 25°C.

  本发明包括一种类黄酮包合物，它是一种不含鼠李糖苷结构的类黄酮和环状寡糖的包合物，环状寡糖选自环糊精、环葡聚糖、环果糖、环麦芽糖和簇状糊精，其中类黄酮部分在 25°C 时在水中的溶解度为 2% 或以上。