ALPHA-榄香醇酸 | 28282-27-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 中文名称: ALPHA-榄香醇酸
• 中文别名: 3-羟基甘遂酸
• 英文名称: 3α-hydroxy-tirucalla-8,24-dien-21-oic acid
• 英文别名: alpha-Elemolic acid；(2S)-2-[(3R,5R,10S,13S,14S,17S)-3-hydroxy-4,4,10,13,14-pentamethyl-2,3,5,6,7,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-methylhept-5-enoic acid
• CAS: 28282-27-1
• 化学式: C₃₀H₄₈O₃
• 分子量: 456.709
• InChiKey: NBSBUIQBEPROBM-IMJUUJEHSA-N

物化性质

• 熔点：
  218-222℃
• 沸点：
  566.9±50.0 °C(Predicted)
• 密度：
  1.07
• 物理描述：
  Solid

计算性质

• 辛醇/水分配系数(LogP)：
  7.5
• 重原子数：
  33
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  57.5
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• Modification of cyclooxygenase and lipoxygenase activity with asteridae extracts and optionally boswellic acid
  申请人：Shaklee Corporation

  公开号：US20040166182A1

  公开（公告）日：2004-08-26

  Extracts from plants in the Asteridae subfamily, such as Carthamus tinctorious , are effective to selectively inhibit COX-2 activity and/or enhance COX-1 activity. When Asteridae extracts are combined with boswellic acid, the combination exhibits a synergistic inhibitory effect on both COX-2 and LO. Such extracts and combinations are used in methods of selectively inhibiting COX-2, inhibiting LO, and/or enhancing COX-1 activity as well as in the methods of treating conditions that would respond favorably to any of these effects.
• US7195790B2
  申请人：——

  公开号：US7195790B2

  公开（公告）日：2007-03-27