Pentanedioic acid mono-[4-((2R,3R,4S,5R,6R)-3,5-bis-benzyloxy-4-hydroxy-6-methoxy-tetrahydro-pyran-2-ylmethoxymethyl)-phenyl] ester | 464177-64-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Pentanedioic acid mono-[4-((2R,3R,4S,5R,6R)-3,5-bis-benzyloxy-4-hydroxy-6-methoxy-tetrahydro-pyran-2-ylmethoxymethyl)-phenyl] ester
• 英文别名: 5-[4-[[(2R,3R,4S,5R,6R)-4-hydroxy-6-methoxy-3,5-bis(phenylmethoxy)oxan-2-yl]methoxymethyl]phenoxy]-5-oxopentanoic acid
• CAS: 464177-64-8
• 化学式: C₃₃H₃₈O₁₀
• 分子量: 594.659
• InChiKey: XAUWCCRQOOJGOW-CQVIXTSXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  43
• 可旋转键数：
  17
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.39
• 拓扑面积：
  130
• 氢给体数：
  2
• 氢受体数：
  10

反应信息

• 作为反应物：
  描述：

  Pentanedioic acid mono-[4-((2R,3R,4S,5R,6R)-3,5-bis-benzyloxy-4-hydroxy-6-methoxy-tetrahydro-pyran-2-ylmethoxymethyl)-phenyl] ester 在 2,3-二氯-5,6-二氰基-1,4-苯醌 作用下， 生成 [(2R,3S,4S,5R,6R)-3,5-Bis-benzyloxy-6-methoxy-4-((3R,4S,5S,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-2-yl]-methanol
  参考文献：
  名称：

  Demixing libraries of saccharides using a multi-linker approach in combination with a soluble polymeric support

  摘要：

  A new method for demixing libraries of compounds that are attached to a soluble polymeric support by tagging starting materials with selective cleavable linkers is described. (C) 2002 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(02)00851-1
• 作为产物：
  描述：

  (2R,3S,4S,5R,6R)-2-(4-Allyloxy-benzyloxymethyl)-5-benzyloxy-6-methoxy-4-(4-methoxy-benzyloxy)-tetrahydro-pyran-3-ol 在 4-二甲氨基吡啶 、 四(三苯基膦)钯 、 sodium hydride 、 三氟乙酸 作用下， 以 吡啶 、 乙醇 、 二氯甲烷 、 N,N-二甲基甲酰胺 为溶剂， 生成 Pentanedioic acid mono-[4-((2R,3R,4S,5R,6R)-3,5-bis-benzyloxy-4-hydroxy-6-methoxy-tetrahydro-pyran-2-ylmethoxymethyl)-phenyl] ester
  参考文献：
  名称：

  Demixing libraries of saccharides using a multi-linker approach in combination with a soluble polymeric support

  摘要：

  A new method for demixing libraries of compounds that are attached to a soluble polymeric support by tagging starting materials with selective cleavable linkers is described. (C) 2002 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(02)00851-1

文献信息

• Demixing libraries of saccharides using a multi-linker approach in combination with a soluble polymeric support
  作者：Galal A. Elsayed、Tong Zhu、Geert-Jan Boons

  DOI：10.1016/s0040-4039(02)00851-1

  日期：2002.5

  A new method for demixing libraries of compounds that are attached to a soluble polymeric support by tagging starting materials with selective cleavable linkers is described. (C) 2002 Elsevier Science Ltd. All rights reserved.