(1R)-3c-isobutyl-2,2-dimethyl-cyclopropane-r-carboxylic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: (1R)-3c-isobutyl-2,2-dimethyl-cyclopropane-r-carboxylic acid
• 英文别名: (1R)-3c-Isobutyl-2,2-dimethyl-cyclopropan-r-carbonsaeure；(1R,3S)-2,2-dimethyl-3-(2-methylpropyl)cyclopropane-1-carboxylic acid
• 化学式: C₁₀H₁₈O₂
• 分子量: 170.252
• InChiKey: ADKZOSLKLWAPEF-YUMQZZPRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  (1R-顺式)-2,2-二甲基-3-(2-甲基丙-1-烯基)环丙烷羧酸 在 乙酸乙酯 、 铂 作用下， 生成 (1R)-3c-isobutyl-2,2-dimethyl-cyclopropane-r-carboxylic acid
  参考文献：
  名称：

  Part-list cuing in amnesic patients: Evidence for a retrieval deficit

  摘要：

  Part-list cuing-the detrimental effect of the presentation of a subset of learned items on recall of the remaining items-was examined in amnesic patients and healthy control subjects. Subjects studied two types of categorized item lists: lists in which each category consisted of strong and moderate items and lists in which each category consisted of weak and moderate items. The subjects recalled a category's strong and weak items in either the presence of or absence of the moderate items serving as retrieval cues. In healthy subjects, part-list cuing impaired recall of the strong items but not of the weak items; in amnesics, part-list cuing impaired recall of both types of items. Part-list cuing is often attributed to a change in the retrieval process from a more effective one when cues are. absent to a less effective one when they are present. On the basis of this view, our results indicate that part-list cuing causes a stronger retrieval inefficiency in amnesic patients than in healthy people.

  DOI：

  10.3758/bf03195772

文献信息

• Part-list cuing in amnesic patients: Evidence for a retrieval deficit
  作者：Karl-Heinz Bäuml、Johanna Kissler、Annette Rak

  DOI：10.3758/bf03195772

  日期：2002.9

  Part-list cuing-the detrimental effect of the presentation of a subset of learned items on recall of the remaining items-was examined in amnesic patients and healthy control subjects. Subjects studied two types of categorized item lists: lists in which each category consisted of strong and moderate items and lists in which each category consisted of weak and moderate items. The subjects recalled a category's strong and weak items in either the presence of or absence of the moderate items serving as retrieval cues. In healthy subjects, part-list cuing impaired recall of the strong items but not of the weak items; in amnesics, part-list cuing impaired recall of both types of items. Part-list cuing is often attributed to a change in the retrieval process from a more effective one when cues are. absent to a less effective one when they are present. On the basis of this view, our results indicate that part-list cuing causes a stronger retrieval inefficiency in amnesic patients than in healthy people.