N-[3-(4-chlorophenylsulfonyl)-4-hydroxy-5-isopropyl-2-methylphenyl]-4-methoxybenzenesulfonamide | 924825-77-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: N-[3-(4-chlorophenylsulfonyl)-4-hydroxy-5-isopropyl-2-methylphenyl]-4-methoxybenzenesulfonamide
• 英文别名: N-[3-(4-chlorophenyl)sulfonyl-4-hydroxy-2-methyl-5-propan-2-ylphenyl]-4-methoxybenzenesulfonamide
• CAS: 924825-77-4
• 化学式: C₂₃H₂₄ClNO₆S₂
• 分子量: 510.032
• InChiKey: MIUVGQDXMFXWPI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.5
• 重原子数：
  33
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  127
• 氢给体数：
  2
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  N-(5-isopropyl-2-methyl-4-oxocyclohexa-2,5-dien-1-ylidene)-4-methoxybenzenesulfonamide 、 sodium p-chlorobenzenesulphinate 以 溶剂黄146 为溶剂， 以91%的产率得到N-[3-(4-chlorophenylsulfonyl)-4-hydroxy-5-isopropyl-2-methylphenyl]-4-methoxybenzenesulfonamide
  参考文献：
  名称：

  Reaction of N-substituted 2,5-dialkyl-1,4-benzoquinone imines with arenesulfinic acids

  摘要：

  Reactions of N-aroyl-, N-arylsulfonyl-, and N-(N-arylsulfonylbenzimidoyl)-2,5-dialkyl-1,4-benzoquinone imines with sodium arenesulfinates in acetic acid gave the corresponding 1,4-, 6,1-, and 1,6-addition products. Variation of the size and donor power of substituents in positions 2 and 5 of the quinoid ring almost does not affect the ratio of the addition products, which is determined mainly by the nature of substituent on the nitrogen atom.

  DOI：

  10.1134/s1070428009030063

文献信息

• Reaction of N-substituted 2,5-dialkyl-1,4-benzoquinone imines with arenesulfinic acids
  作者：A. P. Avdeenko、S. A. Konovalova、D. A. Roman’kov、O. N. Ludchenko、I. L. Marchenko

  DOI：10.1134/s1070428009030063

  日期：2009.3

  Reactions of N-aroyl-, N-arylsulfonyl-, and N-(N-arylsulfonylbenzimidoyl)-2,5-dialkyl-1,4-benzoquinone imines with sodium arenesulfinates in acetic acid gave the corresponding 1,4-, 6,1-, and 1,6-addition products. Variation of the size and donor power of substituents in positions 2 and 5 of the quinoid ring almost does not affect the ratio of the addition products, which is determined mainly by the nature of substituent on the nitrogen atom.