3-hydroxy-6-isopropyl-2-methylquinoline-4-carboxylic acid | 147613-92-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 3-hydroxy-6-isopropyl-2-methylquinoline-4-carboxylic acid
• 英文别名: 4-Quinolinecarboxylic acid, 3-hydroxy-2-methyl-6-(1-methylethyl)-；3-hydroxy-2-methyl-6-propan-2-ylquinoline-4-carboxylic acid
• CAS: 147613-92-1
• 化学式: C₁₄H₁₅NO₃
• 分子量: 245.278
• InChiKey: GOOXHQZIIGBGAM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  18
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  70.4
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  3-hydroxy-6-isopropyl-2-methylquinoline-4-carboxylic acid 在 氯化亚砜 、 N,N-二甲基甲酰胺 作用下， 以 N-甲基吡咯烷酮 、 氯苯 为溶剂， 反应 17.0h， 生成 4H-1,2,4-三唑-4-乙酸,3-甲基-,酰肼
  参考文献：
  名称：

  [EN] A PROCESS FOR PREPARATION OF QUINOPHTHALONE DERIVATIVES
  [FR] PROCÉDÉ DE PRÉPARATION DE DÉRIVÉS DE QUINOPHTALONE

  摘要：

  本公开涉及一种制备喹酮酞衍生物的过程。喹酮酞衍生物被用作许多商业重要化合物的中间体，例如用于合成纤维、塑料和喷墨记录染料的颜料和染料。一些喹酮酞衍生物也被用于液晶组合物和传热染料。本公开提供了一种简单经济的制备公式I的喹酮酞化合物的方法，产率高且纯度高。

  公开号：

  WO2018091979A1

文献信息

• Quinophthalone dyes, ink composition and transfer sheet containing them
  申请人：MITSUI TOATSU CHEMICALS, Inc.

  公开号：EP0527051A1

  公开（公告）日：1993-02-10

  A dyestuff for heat-sensitive transfer record is here disclosed which can be represented by the formula (1) wherein R₁ is a hydrogen atom, alkyl group having 1 to 8 carbon atoms or cycloalkyl group; R₂ is a hydrogen atom, halogen atom, alkoxy group which may be substituted, alkylthio group which may be substituted or arylthio group which may be substituted; R₃ is a branched alkyl group having 3 to 5 carbon atoms, O-substituted oxycarbonyl group, N-substituted aminocarbonyl group in which an N-substituted group may form a ring, or a substituted or unsubstituted heterocyclic ring having two or more atoms of one or more kinds selected from the group consisting of a nitrogen atom, oxygen atom and sulfur atom; and when R₁ is a hydrogen atom, R₃ is a branched alkyl group having 3 to 5 carbon atoms, or a substituted or unsubstituted heterocyclic ring having two or more atoms of one or more kinds selected from the group consisting of a nitrogen atom, oxygen atom and sulfur atom; and there are also disclosed an ink for heat-sensitive transfer record and a transfer sheet in which the above-mentioned dyestuff is used.

  这里公开了一种用于热敏转移记录的染料，它可以用式（1）来表示 其中 R₁ 是氢原子、具有 1 至 8 个碳原子的烷基或环烷基；R₂ 是氢原子、卤素原子、可被取代的烷氧基、可被取代的烷硫基或可被取代的芳硫基；R₃ 是具有 3 至 5 个碳原子的支链烷基、O-取代的氧羰基、N-取代的氨基羰基（其中 N-取代的基团可形成一个环）或取代或未取代的杂环，该杂环具有两个或两个以上选自氮原子、氧原子和硫原子组成的组中的一种或多种原子；当 R₁ 是氢原子时，R₃ 是具有 3 至 5 个碳原子的支链烷基，或具有两个或两个以上从氮原子、氧原子和硫原子组成的组中选出的一种或多种原子的取代或未取代杂环；还公开了一种用于热敏转印记录的油墨和一种转印纸，其中使用了上述染料。
• Quinophthalone compound
  申请人：MITSUI TOATSU CHEMICALS, Inc.

  公开号：EP0527049A1

  公开（公告）日：1993-02-10

  A novel quinophthalone compound is here disclosed which is represented by the formula (1) [wherein when R₁ is an alkyl group having 8 or less carbon atoms which may branch, or cycloalkyl group, R₂ is a hydrogen atom, halogen atom, alkoxy group which may be substituted, alkylthio group, arylthio group which may be substituted, each of R₃ and R₄ is a hydrogen atom, alkyl group, N-substituted aminocarbonyl group, or substituted or unsubstituted heterocyclic ring having two or more atom of one or more kinds selected from the group consisting of a nitrogen atom, oxygen atom and sulfur atom, and R₃ and R₄ may be bonded to each other to form a ring; however, when R₁ is a hydrogen atom, each of R₃ and R₄ is a hydrogen atom, or substituted or unsubstituted heterocyclic ring having two or more atoms of one or more kinds selected from the group consisting of a nitrogen atom, oxygen atom and sulfur atom]. The above-mentioned compound is useful for coloring of polymeric materials, liquid crystal materials and the like.

  这里公开的一种新型喹酞酮化合物由式（1）表示 [其中，当 R₁ 是具有 8 个或 8 个以下碳原子且可分支的烷基或环烷基时，R₂ 是氢原子、卤素原子、可被取代的烷氧基、烷硫基、可被取代的芳硫基，R₃ 和 R₄ 各为氢原子、R₃和 R₄ 均为氢原子、烷基、N-取代的氨基羰基、或具有两个或两个以上从氮原子、氧原子和硫原子组成的组中选出的一种或多种原子的取代或未取代的杂环，且 R₃ 和 R₄ 可相互键合形成环； 然而，当 R₁ 是氢原子时，R₃ 和 R₄ 中的每一个都是氢原子，或具有两个或两个以上选自氮原子、氧原子和硫原子组成的组中的一种或多种原子的取代或未取代杂环]。 上述化合物可用于聚合物材料、液晶材料等的着色。
• YELLOW COMPOUND AND WATER-BASED INK-JET RECORDING INK CONTAINING THE COMPOUND
  申请人：Mitsui Chemicals, Inc.

  公开号：EP1125990A1

  公开（公告）日：2001-08-22

  Aqueous ink for ink-jet recording which contains at least a water-insoluble coloring matter, water and a resin as main components and which takes the form of an emulsion, in which is characterized by containing at least one yellow hue coloring matter selected from the group consisting of a quinophthalone compound represented by the formula (1); and a pyridone azo compound represented by the formula (2); The ink is ink for ink-jet recording having excellent light resistance and storage stability, and enables formation of a high quality image without blotting, and obtained recording image is excellent in water resistance as ink for ink-jet recording.

  喷墨记录用水性墨水，至少含有一种水不溶性着色剂、水和一种树脂作为主要成分，呈乳液状，其特征在于至少含有一种黄色色调着色剂，该着色剂选自由式（1）代表的喹酞酮化合物 和式 (2) 所代表的吡啶酮偶氮化合物； 该墨水是喷墨记录用墨水，具有优异的耐光性和储存稳定性，可形成高质量图像而无需晕染，所获得的记录图像作为喷墨记录用墨水具有优异的耐水性。
• JPH0539269A
  申请人：——

  公开号：JPH0539269A

  公开（公告）日：1993-02-19
• CURABLE COLORING COMPOSITION, COLOR FILTER AND METHOD FOR PRODUCING SAME, AND QUINOPHTHALONE DYE
  申请人：Fujie Yoshihiko

  公开号：US20120112142A1

  公开（公告）日：2012-05-10

  To provide a curable coloring composition that has good color hue, high transmittance properties, high light fastness and heat fastness, and excellent stability over time and solvent resistance after curing, a color filter that has good color hue, high transmittance properties, and excellent light fastness, heat fastness, and solvent resistance, and is compatible with high resolution, and a method for producing same. A curable coloring composition that includes at least one type of quinophthalone dye represented by Formula (1), a color filter employing the curable coloring composition, a method for producing the color filter, and a quinophthalone dye represented by Formula (2).