骨骼肌松弛药
简称肌松药。这类药物作用于神经肌肉接头处，阻碍神经冲动的正常传递，从而导致骨骼肌松弛。它们在化学结构上均含有双季胺基团。主要作为全身麻醉的辅助用药或制动保定药。
根据作用方式的不同，肌松药可分为以下几类：
- 非去极化型肌松药（竞争型肌松药），如筒箭毒碱（α-tubocurarine）和三碘季胺酚（gallamine triethiodide）。
- 去极化型肌松药，如琥珀胆碱（succinycholine）。
此外，还有一种中枢型肌松药，主要用于缓解脑性或脊髓性肌肉痉挛状态，包括安宁、安定、利眠宁和唛酚生等。
| 中文名称 | 英文名称 | CAS号 | 化学式 |
|---|---|---|---|
| 阿曲库铵 | Atracurium | 64228-79-1 | C53H72N2O12 |
| 苯丙氨酯 | phenprobamate | 673-31-4 | C10H13NO2 |
| 艾哌瑞松 | eperisone | 64840-90-0 | C17H25NO |
| 羟乙桂胺 | N-(Hydroxy-2-aethyl)-cinnamid | 6961-46-2 | C11H13NO2 |
| 美他沙酮 | metaxalone | 1665-48-1 | C12H15NO3 |
| 罗库溴铵 | rocuronium bromide | 119302-91-9 | Br*C32H53N2O4 |
| 罗库溴胺 | Rocuronium | 143558-00-3 | C32H53N2O4+ |
| 维库溴铵 | vecuronium bromide | 50700-72-6 | Br*C34H57N2O4 |
| 米库氯铵 | Mivacurium Chloride | 106861-44-3 | C58H80Cl2N2O14 |
| 硫秋水仙苷 | thiocolchicoside | 602-41-5 | C27H33NO10S |
| 盐酸乙哌立松 | eperisone hydrochloride | 56839-43-1 | C17H25NO*ClH |
| 环苯扎林 | Cyclobenzaprine | 303-53-7 | C20H21N |
| 溴己氨胆碱 | N-[6-[[oxido-[2-(trimethylazaniumyl)ethoxy]methylidene]amino]hexyl]-1-[2-(trimethylazaniumyl)ethoxy]methanimidate;dihydrobromide | 306-41-2 | C18H40Br2N4O4 |
| 泮库溴铵 | Pancuronium Bromide | 15500-66-0 | C35H60Br2N2O4 |
| 氯唑沙宗 | 5-chloro-2-benzoxazolinone | 95-25-0 | C7H4ClNO2 |
| 氯化琥珀胆碱 | Succinylcholine Chloride | 71-27-2 | C14H30N2O4.2Cl |
| 氯二甲箭毒 | Dimethyltubocurarinium chloride | 33335-58-9 | C40H48Cl2N2O6 |
| 氟美吗酮 | 6-(4-(trifluoromethyl)phenyl)morpholin-3-one | 7125-73-7 | C11H10F3NO2 |
| 氟喹酮 | Afloqualone | 56287-74-2 | C16H14FN3O |
| 氟乙西泮 | 7-Chlor-1-(2,2,2-trifluorethyl)-5-(2'-fluorphenyl)-2,3-dihydro-1H-1,4-benzodiazepin | 34482-99-0 | C17H13ClF4N2 |
| 曲美布汀马来酸盐 | Cerekinon | 34140-59-5 | C4H4O4*C22H29NO5 |
| 曲美布汀 | trimebutine | 58997-89-0 | C22H29NO5 |
| 昔美酸沙美特罗 | salmeterol xinafoate | 94749-08-3 | C11H8O3*C25H37NO4 |
| 巴氯芬 | 4-amino-3-(4-chlorophenyl)butanoic acid | 1134-47-0 | C10H12ClNO2 |
| 头孢他啶侧链酸活性酯 | Paramyon | 604-92-2 | C24H38I2N2 |
| 哌库溴铵 | Pipecuronium Bromide | 52212-02-9 | C35H62Br2N4O4 |
| 十烃溴铵 | Decamethonium Bromide | 541-22-0 | C16H38Br2N2 |
| 匹维溴铵 | Pinaverium bromide | 53251-94-8 | Br*C26H41BrNO4 |
| 加拉碘铵 | Gallamine Triethiodide | 65-29-2 | C30H60I3N3O3 |
| 依酚氯铵 | edrophonium chloride | 116-38-1 | C10H16NO*Cl |
| 乙基-(3-羟基苯基)-二甲基氯化铵 | Edrophonium | 312-48-1 | C10H16NO+ |
| 丹曲林钠 | Dantroleno sodium | 14663-23-1 | C14H10N4NaO5 |
| (2beta,3alpha,5alpha,16beta,17beta)-3,17-二乙酰氧基-16-(1-甲基-1-哌啶鎓基)-2-(1-哌啶基)雄甾烷 | Vecuronium | 86029-43-8 | C34H57N2O4+ |
| —— | sodium;1-[(E)-[5-(4-nitrophenyl)furan-2-yl]methylideneamino]imidazolidine-2,4-dione | 24868-20-0 | C14H10N4NaO5+ |
| —— | <i>meso</i>-hexa-<i>N</i>-methyl-4,4'-(1,2-diethyl-ethanediyl)-di-anilinium; diiodide | 604-92-2 | C24H38N2*2I |
| —— | 2β,16α-bis(4',4'-dimethyl-1'-piperazino)-3α,17α-diacetoxy-5α-androstane dibromide | 52212-02-9 | 2Br*C35H62N4O4 |
| —— | 2β,16β-bis(4',4'-dimethyl-1'-piperazino)-3α,17α-diacetoxy-5α-androstane dibromide | 52212-02-9 | 2Br*C35H62N4O4 |
| —— | 15500-66-0 | 2Br*C35H60N2O4 | |
| —— | Vecuronium bromide | 50700-72-6 | Br*C34H57N2O4 |
| —— | Dantamacrin | 24868-20-0 | C28H32N8Na2O17 |
| —— | Poncuronium bromide | 15500-66-0 | C35H60BrN2O4+ |
| —— | Dantrolene sodium salt | 14663-23-1 | C14H10N4NaO5 |
| —— | (E)-but-2-enedioic acid;[2-(dimethylamino)-2-phenylbutyl] 3,4,5-trimethoxybenzoate | 34140-59-5 | C22H29NO5.C4H4O4 |
| —— | Dantrolene Sodium Hydrate | 24868-20-0 | C28H32N8Na2O17 |
| —— | decamethonium bromide | 541-22-0 | 2Br*C16H38N2 |
| —— | pancuronium bromide | 15500-66-0 | 2Br*C35H60N2O4 |
| —— | gallamine triiodoethylate | 65-29-2 | C30H60N3O3*3I |
| —— | succinylcholine chloride | 71-27-2 | C14H30N2O4*2Cl |
| —— | dantrolene sodium | 14663-23-1 | C14H9N4O5*Na |
| —— | Musco-ril | 602-41-5 | C27H33NO10S |
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