ethyl (ethyl 4,5,6-tri-O-benzyl-2-deoxy-3-thio-α-L-fuco-3-octulopyranosid)onate | 168568-28-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: ethyl (ethyl 4,5,6-tri-O-benzyl-2-deoxy-3-thio-α-L-fuco-3-octulopyranosid)onate
• CAS: 168568-28-3
• 化学式: C₃₃H₄₀O₆S
• 分子量: 564.743
• InChiKey: ASGGLEHVUIICID-SKMAMYAWSA-N

反应信息

• 作为反应物：
  描述：

  ethyl (ethyl 4,5,6-tri-O-benzyl-2-deoxy-3-thio-α-L-fuco-3-octulopyranosid)onate 在 lithium aluminium tetrahydride 作用下， 以 四氢呋喃 为溶剂， 反应 15.0h， 生成 ethyl 4,5,6-tri-O-benzyl-2-deoxy-3-thio-α-L-fuco-3-octulopyranoside
  参考文献：
  名称：

  Synthesis and glycosylating properties of ketopyranosyl donors

  摘要：

  The preparation of heptulopyranosyl donors 13-15, 28, 29 and 3-octulopyranosyl donors 34, 35, having a non-participating group at C-3 or C-4, respectively, is described. Glycosylations of various accepters with these donors gave exclusively cc-linked ketosides. On the other hand, condensation of 3-O-benzoyl heptulopyranosyl donor 19 with art acceptor furnished an anomeric mixture of ketodisaccharides.

  DOI：

  10.1016/0040-4020(95)00225-w
• 作为产物：
  描述：

  ethyl 4,5,6-tri-O-benzyl-2-deoxy-3-O-trimethylsilyl-α-L-fuco-3-octulopyranosonate 、 乙硫醇 在 三氟甲磺酸三甲基硅酯 、 4 A molecular sieve 作用下， 以 二氯甲烷 为溶剂， 反应 0.17h， 以94%的产率得到ethyl (ethyl 4,5,6-tri-O-benzyl-2-deoxy-3-thio-α-L-fuco-3-octulopyranosid)onate
  参考文献：
  名称：

  Synthesis and glycosylating properties of ketopyranosyl donors

  摘要：

  The preparation of heptulopyranosyl donors 13-15, 28, 29 and 3-octulopyranosyl donors 34, 35, having a non-participating group at C-3 or C-4, respectively, is described. Glycosylations of various accepters with these donors gave exclusively cc-linked ketosides. On the other hand, condensation of 3-O-benzoyl heptulopyranosyl donor 19 with art acceptor furnished an anomeric mixture of ketodisaccharides.

  DOI：

  10.1016/0040-4020(95)00225-w