2,2-Dimethyl-propionic acid (2R,3R,4S,5R,6S)-5-acetoxy-6-[(2R,3S,4R,5R,6R)-4-acetoxy-2-benzyloxymethyl-5-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-6-methoxy-tetrahydro-pyran-3-yloxy]-3,4-dihydroxy-tetrahydro-pyran-2-ylmethyl ester | 187938-33-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2,2-Dimethyl-propionic acid (2R,3R,4S,5R,6S)-5-acetoxy-6-[(2R,3S,4R,5R,6R)-4-acetoxy-2-benzyloxymethyl-5-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-6-methoxy-tetrahydro-pyran-3-yloxy]-3,4-dihydroxy-tetrahydro-pyran-2-ylmethyl ester
• CAS: 187938-33-6
• 化学式: C₃₇H₄₅NO₁₅
• 分子量: 743.762
• InChiKey: ZGMCCJNRGVZNCC-QHCIZUIGSA-N

反应信息

• 作为反应物：
  描述：

  2,2-Dimethyl-propionic acid (2R,3R,4S,5R,6S)-5-acetoxy-6-[(2R,3S,4R,5R,6R)-4-acetoxy-2-benzyloxymethyl-5-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-6-methoxy-tetrahydro-pyran-3-yloxy]-3,4-dihydroxy-tetrahydro-pyran-2-ylmethyl ester 、 2,2-Dimethyl-propionic acid (2R,3S,4S,5R,6S)-3,4,5-triacetoxy-6-[(2R,3S,4R,5R,6S)-4-acetoxy-2-benzyloxymethyl-5-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-6-phenylsulfanyl-tetrahydro-pyran-3-yloxy]-tetrahydro-pyran-2-ylmethyl ester 在 N-碘代丁二酰亚胺 、 三氟甲磺酸 作用下， 反应 1.0h， 以54%的产率得到
  参考文献：
  名称：

  Synthesis of 3-O-sialyl and 6-O-sulfo derivatives of dimeric N-acetyl lactosamine as specific acceptors for α-l-fucosyltransferases

  摘要：

  3-O-唾液酰基和6-O-磺基二聚乳糖胺衍生物1-4的立体选择性合成可通过使用关键的糖基供体13和15来实现。

  DOI：

  10.1039/a605439k
• 作为产物：
  描述：

  2,2-Dimethyl-propionic acid (3aS,4R,6S,7R,7aS)-7-acetoxy-6-[(2R,3S,4R,5R,6R)-4-acetoxy-2-benzyloxymethyl-5-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-6-methoxy-tetrahydro-pyran-3-yloxy]-2,2-dimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran-4-ylmethyl ester 在 溶剂黄146 作用下， 反应 2.5h， 以66%的产率得到2,2-Dimethyl-propionic acid (2R,3R,4S,5R,6S)-5-acetoxy-6-[(2R,3S,4R,5R,6R)-4-acetoxy-2-benzyloxymethyl-5-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-6-methoxy-tetrahydro-pyran-3-yloxy]-3,4-dihydroxy-tetrahydro-pyran-2-ylmethyl ester
  参考文献：
  名称：

  Synthesis of 3-O-sialyl and 6-O-sulfo derivatives of dimeric N-acetyl lactosamine as specific acceptors for α-l-fucosyltransferases

  摘要：

  3-O-唾液酰基和6-O-磺基二聚乳糖胺衍生物1-4的立体选择性合成可通过使用关键的糖基供体13和15来实现。

  DOI：

  10.1039/a605439k