45-O-(2-hydroxyethyl)-trallyl ziracin | 226074-44-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 45-O-(2-hydroxyethyl)-trallyl ziracin
• CAS: 226074-44-8
• 化学式: C₈₁H₁₁₃Cl₂NO₃₉
• 分子量: 1795.68
• InChiKey: UXVCQXGPTQINCZ-ZPYULCSZSA-N

反应信息

• 作为反应物：
  描述：

  45-O-(2-hydroxyethyl)-trallyl ziracin 在 四(三苯基膦)钯 、 三正丁基氢锡 、 zinc(II) chloride 作用下， 以 四氢呋喃 为溶剂， 生成
  参考文献：
  名称：

  Chemical modifications and structure activity studies of ziracin and related everninomicin antibiotics

  摘要：

  Chemical modifications of everninomicin antibiotics, particularly ziracin (1), were carried out to study the SARs as well as the chemical properties of this class of compounds. Use of allyl ether group for protection and selective deprotection of phenolic groups provided access to a variety of novel analogs of the title compounds, some of which exhibited the same high in vitro potency as the parent compounds. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0960-894x(99)00163-8
• 作为产物：
  描述：

  在 四丁基氟化铵 作用下， 以 四氢呋喃 为溶剂， 生成 45-O-(2-hydroxyethyl)-trallyl ziracin
  参考文献：
  名称：

  Chemical modifications and structure activity studies of ziracin and related everninomicin antibiotics

  摘要：

  Chemical modifications of everninomicin antibiotics, particularly ziracin (1), were carried out to study the SARs as well as the chemical properties of this class of compounds. Use of allyl ether group for protection and selective deprotection of phenolic groups provided access to a variety of novel analogs of the title compounds, some of which exhibited the same high in vitro potency as the parent compounds. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0960-894x(99)00163-8