2-aminoethyl 4-O-acetyl-2,6-di-O-benzoyl-3-O-sulfo-β-D-galactopyranosyl-(1->3)-2-acetamido-2-deoxy-β-D-galactopyranosyl-(1->4)-3-O-sulfo-β-D-galactopyranosyl-(1->4)-β-D-glucopyranoside | 503159-56-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-aminoethyl 4-O-acetyl-2,6-di-O-benzoyl-3-O-sulfo-β-D-galactopyranosyl-(1->3)-2-acetamido-2-deoxy-β-D-galactopyranosyl-(1->4)-3-O-sulfo-β-D-galactopyranosyl-(1->4)-β-D-glucopyranoside
• CAS: 503159-56-6
• 化学式: C₄₄H₆₀N₂O₃₀S₂
• 分子量: 1161.09
• InChiKey: LPBOSQSMDHPRMP-PPNCVNEFSA-N

反应信息

• 作为反应物：
  描述：

  2-aminoethyl 4-O-acetyl-2,6-di-O-benzoyl-3-O-sulfo-β-D-galactopyranosyl-(1->3)-2-acetamido-2-deoxy-β-D-galactopyranosyl-(1->4)-3-O-sulfo-β-D-galactopyranosyl-(1->4)-β-D-glucopyranoside 在 sodium methylate 作用下， 以 甲醇 为溶剂， 反应 6.0h， 以90%的产率得到2-aminoethyl 3-O-sulfo-β-D-galactopyranosyl-(1->3)-2-acetamido-2-deoxy-β-D-galactopyranosyl-(1->4)-3-O-sulfo-β-D-galactopyranosyl-(1->4)-β-D-glucopyranoside
  参考文献：
  名称：

  Synthesis of a spacer-armed disulfated tetrasaccharide of SB1a, a carbohydrate hapten associated with human hepatocellular carcinoma

  摘要：

  A disulfated tetrasaccharide fragment with a spacer arm of human hepatocellular carcinoma carbohydrate antigen SB1a, namely, 2-aminoethyl 3-O-sulfo-beta-D-galactopyranosyl-(1 --> 3)-2-acetamido-2-deoxy-beta-D-galactopyranosyl-(1 --> 4)-3-O-sulfo-beta-D-galactopyranosyl-(1 --> 4)-beta-D-glucopyranoside was synthesized via a [2 + 1 + 1] block building mode. In the last coupling step toward the trisaccharide acceptor 8, benzoyl protected galactosyl bromide donor 14 was found to be much more reactive than the acetyl-protected donors. (C) 2002 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0008-6215(02)00291-4
• 作为产物：
  描述：

  2-azidoethyl 4-O-acetyl-2,6-di-O-benzoyl-3-O-sulfo-β-D-galactopyranosyl-(1->3)-2-acetamido-4,6-O-benzylidene-2-deoxy-β-D-galactopyranosyl-(1->4)-2,6-di-O-benzyl-3-O-sulfo-β-D-galactopyranosyl-(1->4)-2,3,6-tri-O-benzyl-β-D-glucopyranoside 在 palladium on activated charcoal 盐酸 、 氢气 作用下， 以 甲醇 、 水 为溶剂， 反应 60.0h， 以88%的产率得到2-aminoethyl 4-O-acetyl-2,6-di-O-benzoyl-3-O-sulfo-β-D-galactopyranosyl-(1->3)-2-acetamido-2-deoxy-β-D-galactopyranosyl-(1->4)-3-O-sulfo-β-D-galactopyranosyl-(1->4)-β-D-glucopyranoside
  参考文献：
  名称：

  Synthesis of a spacer-armed disulfated tetrasaccharide of SB1a, a carbohydrate hapten associated with human hepatocellular carcinoma

  摘要：

  A disulfated tetrasaccharide fragment with a spacer arm of human hepatocellular carcinoma carbohydrate antigen SB1a, namely, 2-aminoethyl 3-O-sulfo-beta-D-galactopyranosyl-(1 --> 3)-2-acetamido-2-deoxy-beta-D-galactopyranosyl-(1 --> 4)-3-O-sulfo-beta-D-galactopyranosyl-(1 --> 4)-beta-D-glucopyranoside was synthesized via a [2 + 1 + 1] block building mode. In the last coupling step toward the trisaccharide acceptor 8, benzoyl protected galactosyl bromide donor 14 was found to be much more reactive than the acetyl-protected donors. (C) 2002 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0008-6215(02)00291-4