1-allyl-3-(5-chloro-2-methoxyphenylaminomethylene)quinoline-2,4-(1H,3H)-dione | 1226970-49-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 1-allyl-3-(5-chloro-2-methoxyphenylaminomethylene)quinoline-2,4-(1H,3H)-dione
• CAS: 1226970-49-5
• 化学式: C₂₀H₁₇ClN₂O₃
• 分子量: 368.82
• InChiKey: FEXQRXVINWSQCR-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  1-allyl-3-(5-chloro-2-methoxyphenylaminomethylene)quinoline-2,4-(1H,3H)-dione 在 溴 、 溶剂黄146 、 水 作用下， 以61%的产率得到2-bromomethyl-5-oxo-1,2-dihydro-5H-oxazolo[3,2-a]quinoline-4-carbaldehyde
  参考文献：
  名称：

  4-hydroxy-2-quinolones. 169*. synthesis and bromination of 1-allyl-3-(arylamino-methylene)quinoline-2,4-(1h,3h)-diones

  摘要：

  Bromination of 1-allyl-substituted 3-(arylaminomethylene)quinoline-2,4-(1H,3H)-diones with one equivalent of molecular bromine in glacial acetic acid and subsequent dilution of the reaction mixture with water is accompanied by halocyclization and hydrolysis to form 2-bromomethyl-5-oxo-1,2 dihydro-5H- oxazolo[3,2-a]quinoline-4-carbaldehyde.

  DOI：

  10.1007/s10593-010-0412-6