(2R,4R)-1,2-cyclohexylidenedioxy-4-methyl-5-hexen-3-one | 1196678-56-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2R,4R)-1,2-cyclohexylidenedioxy-4-methyl-5-hexen-3-one
• CAS: 1196678-56-4
• 化学式: C₁₃H₂₀O₃
• 分子量: 224.3
• InChiKey: MZGJPWVXHCRYSH-GHMZBOCLSA-N

反应信息

• 作为反应物：
  描述：

  (2R,4R)-1,2-cyclohexylidenedioxy-4-methyl-5-hexen-3-one 在 potassium tri-sec-butyl-borohydride 作用下， 以 四氢呋喃 为溶剂， 生成 (2R,3R,4R)-1,2-cyclohexylidenedioxy-4-methylhex-5-en-3-ol
  参考文献：
  名称：

  Metal-dependent modulation of diastereoselectivity in the Barbier-type crotylation of (R)-cyclohexylideneglyceraldehyde

  摘要：

  The diastereoselectivity of the Barbier-type crotylation of (R)-cyclohexylideneglyceraldehyde could be tuned by changing the metal atom and solvent. The Ga-mediated reaction in [bmim][Br] produced the best diastereoselectivity, furnishing the all-anti product in good yield. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2009.08.013
• 作为产物：
  描述：

  (2R,3S,4R)-1,2-cyclohexylidenedioxy-4-methylhex-5-en-3-ol 在 sodium acetate 、 pyridinium chlorochromate 作用下， 以 二氯甲烷 为溶剂， 反应 3.0h， 以75%的产率得到(2R,4R)-1,2-cyclohexylidenedioxy-4-methyl-5-hexen-3-one
  参考文献：
  名称：

  Metal-dependent modulation of diastereoselectivity in the Barbier-type crotylation of (R)-cyclohexylideneglyceraldehyde

  摘要：

  The diastereoselectivity of the Barbier-type crotylation of (R)-cyclohexylideneglyceraldehyde could be tuned by changing the metal atom and solvent. The Ga-mediated reaction in [bmim][Br] produced the best diastereoselectivity, furnishing the all-anti product in good yield. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2009.08.013