dibenzyl (3,4,6-tri-O-benzyl-2-deoxy-α-D-lyxo-hexopyranosyl)-1-phosphate | 1190870-90-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: dibenzyl (3,4,6-tri-O-benzyl-2-deoxy-α-D-lyxo-hexopyranosyl)-1-phosphate
• CAS: 1190870-90-6
• 化学式: C₄₁H₄₃O₈P
• 分子量: 694.761
• InChiKey: YVWPURDCFLQYJY-GAKQXGIYSA-N

反应信息

• 作为反应物：
  描述：

  dibenzyl (3,4,6-tri-O-benzyl-2-deoxy-α-D-lyxo-hexopyranosyl)-1-phosphate 在 10% palladium on activated carbon 、 氢气 作用下， 以 甲醇 、 水 、 乙酸乙酯 为溶剂， 20.0 ℃ 、5.0 MPa 条件下， 反应 10.0h， 以65%的产率得到Gal2deoxy-1-P
  参考文献：
  名称：

  En route to deoxygenated N-acetyllactosamine analogues employing uridyl and galactosyl transferases

  摘要：

  All monodeoxygenated galactoses were treated with galactokinase, and for the 2-, 3-, and 4-deoxy compounds, transformation into the corresponding galactopyranosyl phosphates could be observed. In case of the 2-deoxy derivative, further reaction via UDP-2-deoxy-D-lyxo-hexose (UDP-2-deoxygalactose), which was also obtained chemically, the multiple enzymatic system could be employed to prepare 2'-deoxy-N-acetyllactosamine. (C) 2009 Elsevier Ltd. Ail rights reserved.

  DOI：

  10.1016/j.carres.2009.05.015
• 作为产物：
  描述：

  在 间氯过氧苯甲酸 作用下， 以 二氯甲烷 为溶剂， 生成 dibenzyl (3,4,6-tri-O-benzyl-2-deoxy-α-D-lyxo-hexopyranosyl)-1-phosphate
  参考文献：
  名称：

  En route to deoxygenated N-acetyllactosamine analogues employing uridyl and galactosyl transferases

  摘要：

  All monodeoxygenated galactoses were treated with galactokinase, and for the 2-, 3-, and 4-deoxy compounds, transformation into the corresponding galactopyranosyl phosphates could be observed. In case of the 2-deoxy derivative, further reaction via UDP-2-deoxy-D-lyxo-hexose (UDP-2-deoxygalactose), which was also obtained chemically, the multiple enzymatic system could be employed to prepare 2'-deoxy-N-acetyllactosamine. (C) 2009 Elsevier Ltd. Ail rights reserved.

  DOI：

  10.1016/j.carres.2009.05.015