6,7-diazabicyclo[3.2.1]oct-6-en-8-ol | 1233348-28-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 6,7-diazabicyclo[3.2.1]oct-6-en-8-ol
• CAS: 1233348-28-1
• 化学式: C₆H₁₀N₂O
• 分子量: 126.158
• InChiKey: RVYPNEHYWPIEHE-FMCRUOTFSA-N

物化性质

• 沸点：
  214.7±29.0 °C(Predicted)
• 密度：
  1.60±0.1 g/cm3(Predicted)

反应信息

• 作为反应物：
  描述：

  6,7-diazabicyclo[3.2.1]oct-6-en-8-ol 在 palladium 10% on activated carbon 、 氢气 作用下， 以 甲醇 为溶剂， 20.0 ℃ 、413.69 kPa 条件下， 反应 9.0h， 以97%的产率得到2,6-diaminocyclohexanol
  参考文献：
  名称：

  On the [3 + 2] Annulation of Cyclic Allylsilanes with N-Phenyltriazolinedione: An Enantio- and Diastereoselective Synthesis of cis-1,3-Diaminocyclitols

  摘要：

  Improved conditions were found to trigger [3 + 2] annulation of cyclic allylsilanes with N-phenyltriazolinedione (PTAD); the products from this reaction were readily tailored into cis-1,3-diaminocyclitols in highly enantioenriched form with full stereochemical control of up to four contiguous stereogenic centers.

  DOI：

  10.1021/jo100724w
• 作为产物：
  描述：

  在 盐酸 、 ammonium hydroxide 、 copper dichloride 作用下， 以 水 、 异丙醇 为溶剂， 以90 mg的产率得到6,7-diazabicyclo[3.2.1]oct-6-en-8-ol
  参考文献：
  名称：

  On the [3 + 2] Annulation of Cyclic Allylsilanes with N-Phenyltriazolinedione: An Enantio- and Diastereoselective Synthesis of cis-1,3-Diaminocyclitols

  摘要：

  Improved conditions were found to trigger [3 + 2] annulation of cyclic allylsilanes with N-phenyltriazolinedione (PTAD); the products from this reaction were readily tailored into cis-1,3-diaminocyclitols in highly enantioenriched form with full stereochemical control of up to four contiguous stereogenic centers.

  DOI：

  10.1021/jo100724w