methyl 5'-acetamido-4',7',8',9'-tetra-O-acetyl-2',6'-anhydro-3',5'-dideoxy-2'-C-(6,7,8-trideoxy-1,2;3,4-di-O-isopropylidene-α-D-galacto-octopyranos-8-yl)-D-erythro-L-manno-nonoate | 1045795-26-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: methyl 5'-acetamido-4',7',8',9'-tetra-O-acetyl-2',6'-anhydro-3',5'-dideoxy-2'-C-(6,7,8-trideoxy-1,2;3,4-di-O-isopropylidene-α-D-galacto-octopyranos-8-yl)-D-erythro-L-manno-nonoate
• CAS: 1045795-26-3
• 化学式: C₃₄H₅₁NO₁₇
• 分子量: 745.775
• InChiKey: SGWMAPZFXFLJGD-AFHPMJFGSA-N

反应信息

• 作为反应物：
  描述：

  methyl 5'-acetamido-4',7',8',9'-tetra-O-acetyl-2',6'-anhydro-3',5'-dideoxy-2'-C-(6,7,8-trideoxy-1,2;3,4-di-O-isopropylidene-α-D-galacto-octopyranos-8-yl)-D-erythro-L-manno-nonoate 在 sodium methylate 作用下， 以 甲醇 为溶剂， 反应 5.0h， 生成
  参考文献：
  名称：

  Cross metathesis for the synthesis of novel C-sialosides

  摘要：

  Cross metathesis of both anomers of C-allyl sialoside (3 alpha/3 beta) with styrene catalyzed by the second generation Grubbs or Hoveyda-Grubbs catalysts gave the corresponding aryl derivatives (4 alpha/4 beta) in virtually quantitative yields. The products were hydrogenated to model compounds 5 alpha/5 beta. Similarly, reaction of the alpha-anomer 3 alpha with galactose derivative 8 gave the olefin-linked disaccharide mimetic 9. Following hydrogenation and deprotection, the ethylene-bridged Neu5Ac alpha(2 -> 6)Gal analogue 11 could be obtained. (c) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carres.2008.03.036
• 作为产物：
  描述：

  在 palladium on activated charcoal 氢气 作用下， 以 甲醇 为溶剂， 以95%的产率得到methyl 5'-acetamido-4',7',8',9'-tetra-O-acetyl-2',6'-anhydro-3',5'-dideoxy-2'-C-(6,7,8-trideoxy-1,2;3,4-di-O-isopropylidene-α-D-galacto-octopyranos-8-yl)-D-erythro-L-manno-nonoate
  参考文献：
  名称：

  Cross metathesis for the synthesis of novel C-sialosides

  摘要：

  Cross metathesis of both anomers of C-allyl sialoside (3 alpha/3 beta) with styrene catalyzed by the second generation Grubbs or Hoveyda-Grubbs catalysts gave the corresponding aryl derivatives (4 alpha/4 beta) in virtually quantitative yields. The products were hydrogenated to model compounds 5 alpha/5 beta. Similarly, reaction of the alpha-anomer 3 alpha with galactose derivative 8 gave the olefin-linked disaccharide mimetic 9. Following hydrogenation and deprotection, the ethylene-bridged Neu5Ac alpha(2 -> 6)Gal analogue 11 could be obtained. (c) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carres.2008.03.036