| 945222-50-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• CAS: 945222-50-4
• 化学式: C₁₄H₁₇NO₅
• 分子量: 279.293
• InChiKey: WAHRDUYGIPPUOS-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  在 palladium on activated charcoal 盐酸羟胺 、 氢气 、 sodium acetate 作用下， 以 乙醇 为溶剂， 生成 Tert-butyl 2-amino-5-(1-aminopropyl)benzoate
  参考文献：
  名称：

  Development of 6-benzyl substituted 4-aminocarbonyl-1,4-diazepane-2,5-diones as orally active human chymase inhibitors

  摘要：

  A novel series of 6-benzyl substituted 4-aminocarbonyl-1,4-diazepane-2,5-diones was designed, synthesized, and evaluated as human chymase inhibitors. From this series, we identified several compounds which were effective, via oral administration, in a mouse model of chronic dermatitis. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2007.03.085
• 作为产物：
  描述：

  在 potassium tert-butylate 、 盐酸 作用下， 以 1,4-二氧六环 为溶剂， 生成
  参考文献：
  名称：

  Development of 6-benzyl substituted 4-aminocarbonyl-1,4-diazepane-2,5-diones as orally active human chymase inhibitors

  摘要：

  A novel series of 6-benzyl substituted 4-aminocarbonyl-1,4-diazepane-2,5-diones was designed, synthesized, and evaluated as human chymase inhibitors. From this series, we identified several compounds which were effective, via oral administration, in a mouse model of chronic dermatitis. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2007.03.085