phenyl 6-O-acetyl-2,4-di-O-benzoyl-3-O-(2-naphthylmethyl)-1-thio-β-D-galactopyranoside | 1190749-39-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: phenyl 6-O-acetyl-2,4-di-O-benzoyl-3-O-(2-naphthylmethyl)-1-thio-β-D-galactopyranoside
• CAS: 1190749-39-3
• 化学式: C₃₉H₃₄O₈S
• 分子量: 662.76
• InChiKey: RCKHBAXPKMGRJX-SZSPXRLCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.26
• 重原子数：
  48.0
• 可旋转键数：
  11.0
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.21
• 拓扑面积：
  97.36
• 氢给体数：
  0.0
• 氢受体数：
  9.0

反应信息

• 作为反应物：
  描述：

  phenyl 6-O-acetyl-2,4-di-O-benzoyl-3-O-(2-naphthylmethyl)-1-thio-β-D-galactopyranoside 在 溴 作用下， 以 二氯甲烷 为溶剂， 反应 1.0h， 生成 (2R,3S,4S,5R,6R)-2-(acetoxymethyl)-6-bromo-4-(naphthalen-2-ylmethoxy)tetrahydro-2H-pyran-3,5-diyl dibenzoate
  参考文献：
  名称：

  Synthesis of 3,6-branched arabinogalactan-type tetra- and hexasaccharides for characterization of monoclonal antibodies

  摘要：

  Synthesis of tetra- and hexasaccharides built up from a beta-(1 -> 6)-linked galactopyranosyl backbone with arabinofuranosyl side chains at position 3 and with a 3-aminopropyl spacer related to arabinogalactans is described. These oligosaccharides were prepared for investigation of monoclonal antibodies raised against arabinogalactan proteins (AGPs) from pressed juice of Echinacea purpurea. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carres.2009.04.025
• 作为产物：
  描述：

  phenyl 2,4-di-O-benzoyl-3-O-(2-naphthylmethyl)-1-thio-β-D-galactopyranoside 、 乙酸酐 在 吡啶 作用下， 反应 2.0h， 以95%的产率得到phenyl 6-O-acetyl-2,4-di-O-benzoyl-3-O-(2-naphthylmethyl)-1-thio-β-D-galactopyranoside
  参考文献：
  名称：

  Synthesis of 3,6-branched arabinogalactan-type tetra- and hexasaccharides for characterization of monoclonal antibodies

  摘要：

  Synthesis of tetra- and hexasaccharides built up from a beta-(1 -> 6)-linked galactopyranosyl backbone with arabinofuranosyl side chains at position 3 and with a 3-aminopropyl spacer related to arabinogalactans is described. These oligosaccharides were prepared for investigation of monoclonal antibodies raised against arabinogalactan proteins (AGPs) from pressed juice of Echinacea purpurea. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carres.2009.04.025