[(2S,3S,6S)-6-[(2R,3R,4R,6S)-3-benzylsulfonyloxy-6-[(2R,3R,4R,6S)-6-[(2S,3S,6S)-6-[(2R,3R,4R,6S)-3-benzylsulfonyloxy-2-methyl-6-[(2R,3R,4R,6S)-2-methyl-4-phenylmethoxy-6-[4-(2-trimethylsilylethoxymethoxy)phenoxy]oxan-3-yl]oxyoxan-4-yl]oxy-2-methyloxan-3-yl]oxy-2-methyl-4-phenylmethoxyoxan-3-yl]oxy-2-methyloxan-4-yl]oxy-2-methyloxan-3-yl] 4-oxopentanoate | 1237527-10-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: [(2S,3S,6S)-6-[(2R,3R,4R,6S)-3-benzylsulfonyloxy-6-[(2R,3R,4R,6S)-6-[(2S,3S,6S)-6-[(2R,3R,4R,6S)-3-benzylsulfonyloxy-2-methyl-6-[(2R,3R,4R,6S)-2-methyl-4-phenylmethoxy-6-[4-(2-trimethylsilylethoxymethoxy)phenoxy]oxan-3-yl]oxyoxan-4-yl]oxy-2-methyloxan-3-yl]oxy-2-methyl-4-phenylmethoxyoxan-3-yl]oxy-2-methyloxan-4-yl]oxy-2-methyloxan-3-yl] 4-oxopentanoate
• CAS: 1237527-10-4
• 化学式: C₈₁H₁₁₀O₂₅S₂Si
• 分子量: 1575.97
• InChiKey: MDUSEKFVPKPYSE-CQNMPTCCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  12.55
• 重原子数：
  109
• 可旋转键数：
  37
• 环数：
  11.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  295
• 氢给体数：
  0
• 氢受体数：
  25

反应信息

• 作为反应物：
  描述：

  [(2S,3S,6S)-6-[(2R,3R,4R,6S)-3-benzylsulfonyloxy-6-[(2R,3R,4R,6S)-6-[(2S,3S,6S)-6-[(2R,3R,4R,6S)-3-benzylsulfonyloxy-2-methyl-6-[(2R,3R,4R,6S)-2-methyl-4-phenylmethoxy-6-[4-(2-trimethylsilylethoxymethoxy)phenoxy]oxan-3-yl]oxyoxan-4-yl]oxy-2-methyloxan-3-yl]oxy-2-methyl-4-phenylmethoxyoxan-3-yl]oxy-2-methyloxan-4-yl]oxy-2-methyloxan-3-yl] 4-oxopentanoate 在 sodium methylate 作用下， 以 四氢呋喃 、 甲醇 为溶剂， 生成
  参考文献：
  名称：

  10.1002/asia.200900640.

  摘要：

  DOI：

  10.1002/asia.200900640.
• 作为产物：
  描述：

  [(2S,3S,6S)-6-[(2R,3R,4R,6S)-3-benzylsulfonyloxy-2-methyl-6-[(2R,3R,4R)-2-methyl-4-phenylmethoxy-6-(2,2,2-trichloroethanimidoyl)oxyoxan-3-yl]oxyoxan-4-yl]oxy-2-methyloxan-3-yl] 4-oxopentanoate 、 [(2R,3R,4R,6S)-4-[(2S,5S,6S)-5-hydroxy-6-methyloxan-2-yl]oxy-2-methyl-6-[(2R,3R,4R,6S)-2-methyl-4-phenylmethoxy-6-[4-(2-trimethylsilylethoxymethoxy)phenoxy]oxan-3-yl]oxyoxan-3-yl] phenylmethanesulfonate 在 三乙基硅烷 、 碘 作用下， 以 甲苯 为溶剂， 反应 3.5h， 生成 [(2S,3S,6S)-6-[(2R,3R,4R,6S)-3-benzylsulfonyloxy-6-[(2R,3R,4R,6S)-6-[(2S,3S,6S)-6-[(2R,3R,4R,6S)-3-benzylsulfonyloxy-2-methyl-6-[(2R,3R,4R,6S)-2-methyl-4-phenylmethoxy-6-[4-(2-trimethylsilylethoxymethoxy)phenoxy]oxan-3-yl]oxyoxan-4-yl]oxy-2-methyloxan-3-yl]oxy-2-methyl-4-phenylmethoxyoxan-3-yl]oxy-2-methyloxan-4-yl]oxy-2-methyloxan-3-yl] 4-oxopentanoate 、 [(2S,3S,6S)-6-[(2R,3R,4R,6S)-3-benzylsulfonyloxy-6-[(2R,3R,4R,6R)-6-[(2S,3S,6S)-6-[(2R,3R,4R,6S)-3-benzylsulfonyloxy-2-methyl-6-[(2R,3R,4R,6S)-2-methyl-4-phenylmethoxy-6-[4-(2-trimethylsilylethoxymethoxy)phenoxy]oxan-3-yl]oxyoxan-4-yl]oxy-2-methyloxan-3-yl]oxy-2-methyl-4-phenylmethoxyoxan-3-yl]oxy-2-methyloxan-4-yl]oxy-2-methyloxan-3-yl] 4-oxopentanoate
  参考文献：
  名称：

  10.1002/asia.200900640.

  摘要：

  DOI：

  10.1002/asia.200900640.