1-Hydroxymethyl-2-octylcyclopropan | 66595-08-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-Hydroxymethyl-2-octylcyclopropan
• 英文别名: (2-Octylcyclopropyl)methanol
• CAS: 66595-08-2
• 化学式: C₁₂H₂₄O
• 分子量: 184.322
• InChiKey: WMLNTZCXPCPNDP-UHFFFAOYSA-N

物化性质

• 沸点：
  239.3±8.0 °C(Predicted)
• 密度：
  0.884±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  13
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1-Hydroxymethyl-2-octylcyclopropan 在 三甲基乙酰氯 、 N,N-二甲基甲酰胺 作用下， 以 二氯甲烷 为溶剂， 反应 0.5h， 以80%的产率得到1-(Chloromethyl)-2-octylcyclopropane
  参考文献：
  名称：

  新戊酰氯/ DMF：一种将醇转化为氯化物的新试剂

  摘要：

  描述了将醇转化为相应的氯化物的有效方法。新戊酰氯/ DMF复合物用作温和且便宜的试剂。提出了一种可能的反应机理。

  DOI：

  10.1016/j.tetlet.2009.11.131
• 作为产物：
  描述：

  2-辛基环丙烷羧酸乙酯 生成 1-Hydroxymethyl-2-octylcyclopropan
  参考文献：
  名称：

  Synthesis and bactericidal properties of quaternary ammonium salts from 2-alkylcyclopropylmethyl bromides

  摘要：

  DOI：

  10.1007/bf00923904

文献信息

• [EN] INCENSE ODORANT<br/>[FR] ODORISANT D'ENCENS
  申请人：FIRMENICH & CIE

  公开号：WO2022207448A1

  公开（公告）日：2022-10-06

  The present invention relates to the field of perfumery. More particularly, it concerns a composition of matter comprising a compound of formula (I) as defined below wherein the weight ratio of the cis-diastereoisomers to the trans-diastereoisomers is comprised in the range between 90:10 and 99.5:0.5 and comprising at least 10% w/w of cis-(1S,2R) diastereoisomer. Said composition of matter is a useful perfumery ingredient, and therefore the present invention comprises the invention composition of matter as part of a perfuming composition or of a perfuming consumer product.

  本发明涉及香料领域，更具体地涉及一种物质组合物，该组合物包括以下公式（I）中定义的化合物，其中顺式异构体与反式异构体的重量比在90:10到99.5:0.5之间，并且至少包含10％w/w的顺式-(1S,2R)对映异构体。所述物质组合物是一种有用的香料成分，因此本发明包括将该发明物质组合物作为香料组合物或香料消费品的一部分的发明。
• 2-octylcyclopropyl-1-carboxylic acid and the isomers thereof, and uses of same
  申请人：Vieille Albert

  公开号：US11236287B2

  公开（公告）日：2022-02-01

  The invention relates to 2-octylcyclopropyl-1-carboxylic acid, in particular in the form of one of the isomers thereof in isolated form or in the form of a mixture of at least two of said isomers. The invention further relates to a method for synthesizing 2-octylcyclopropyl-1-carboxylic acid or at least one of the isomers thereof. Finally, the invention relates to the use of 2-octylcyclopropyl-1-carboxylic acid or of one of said isomers in isolated form or of one of the mixtures of at least two of the isomers thereof, as a perfuming agent. The invention further relates to the compositions including 2-octylcyclopropyl-1-carboxylic acid or one of said isomers in isolated form or one of the mixtures of at least two of the isomers thereof, as a perfuming agent.

  本发明涉及 2-辛基环丙基-1-羧酸，特别是其中一种异构体的分离形式或至少两种异构体的混合物形式。本发明还涉及一种合成 2-辛基环丙基-1-羧酸或其至少一种异构体的方法。最后，本发明涉及 2-辛基环丙基-1-羧酸或上述异构体之一的分离形式或其至少两种异构体的混合物之一作为香水剂的用途。本发明还涉及包括 2-辛基环丙基-1-羧酸或上述异构体之一的单独形式或其至少两种异构体的混合物之一的组合物作为香料。
• EHPSHTEJN A. E.; DOLGIJ I. E.; LIMANOV V. E.; SKVORTSOVA E. K.; NEFEDOV O+, IZV. AN CCCP, CEP. XIM., 1978, HO 2, 500-503
  作者：EHPSHTEJN A. E.、 DOLGIJ I. E.、 LIMANOV V. E.、 SKVORTSOVA E. K.、 NEFEDOV O+

  DOI：——

  日期：——
• ACIDE 2-OCTYLCYCLOPROPYL-1-CARBOXYLIQUE ET SES ISOMÈRES ET UTILISATIONS
  申请人：Albert, Vieille

  公开号：EP3221290A1

  公开（公告）日：2017-09-27
• 2-OCTYLCYCLOPROPYL-1-CARBOXYLIC ACID AND THE ISOMERS THEREOF, AND USES OF SAME
  申请人：VIEILLE ALBERT

  公开号：US20180163157A1

  公开（公告）日：2018-06-14

  The invention relates to 2-octylcyclopropyl-1-carboxylic acid, in particular in the form of one of the isomers thereof in isolated form or in the form of a mixture of at least two of said isomers. The invention further relates to a method for synthesizing 2-octylcyclopropyl-1-carboxylic acid or at least one of the isomers thereof. Finally, the invention relates to the use of 2-octylcyclopropyl-1-carboxylic acid or of one of said isomers in isolated form or of one of the mixtures of at least two of the isomers thereof, as a perfuming agent. The invention further relates to the compositions including 2-octylcyclopropyl-1-carboxylic acid or one of said isomers in isolated form or one of the mixtures of at least two of the isomers thereof, as a perfuming agent.