3,4-bis-(2,4-dimethoxy-phenyl)-4-oxo-butyric acid methyl ester | 54584-19-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3,4-bis-(2,4-dimethoxy-phenyl)-4-oxo-butyric acid methyl ester
• 英文别名: 3,4-Bis-(2,4-dimethoxy-phenyl)-4-oxo-buttersaeure-methylester；methyl 3,4-bis(2,4-dimethoxyphenyl)-4-oxobutanoate
• CAS: 54584-19-9
• 化学式: C₂₁H₂₄O₇
• 分子量: 388.417
• InChiKey: LOCIACFZNONICY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  28
• 可旋转键数：
  10
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  80.3
• 氢给体数：
  0
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  3,4-bis-(2,4-dimethoxy-phenyl)-4-oxo-butyric acid methyl ester 、 氢氧化钾 生成 3,4-Bis-<2,4-dimethoxy-phenyl>-4-keto-buttersaeure
  参考文献：
  名称：

  MOLYNEUX R. J.; JURD L., AUSTRAL. J. CHEM. , 1974, 27, NO 12, 2697-2702

  摘要：

  DOI：
• 作为产物：
  描述：

  间苯二甲醚 在 二硫化碳 、 三氯化铝 作用下， 生成 3,4-bis-(2,4-dimethoxy-phenyl)-4-oxo-butyric acid methyl ester
  参考文献：
  名称：

  Optical tweezers for confocal microscopy

  摘要：

  In confocal laser scanning microscopes (CLSMs), lasers can be used for image formation as well as tools for the manipulation of microscopic objects. In the latter case, in addition to the imaging lasers, the light of an extra laser has to be focused into the object plane of the CLSM, for example as optical tweezers. Imaging as well as trapping by optical tweezers can be done using the same objective lens. In this case, z-sectioning for 3D imaging shifts the optical tweezers with the focal plane of the objective along the optical axis, so that a trapped object remains positioned in the focal plane. Consequently, 3D imaging of trapped objects is impossible without further measures. We present an experimental set-up keeping the axial trapping position of the optical tweezers at its intended position whilst the focal plane can be axially shifted over a distance of about 15 mum. It is based on fast-moving correctional optics synchronized with the objective movement. First examples of application are the 3D imaging of chloroplasts of Elodea densa (Canadian waterweed) in a vigorous cytoplasmic streaming and the displacement of zymogen granules in pancreatic cancer cells (AR42 J).

  DOI：

  10.1007/s003400000454