methyl (α-L-rhamnopyranosyl)-(1->4)-(methyl α-D-galactopyranosyluronate)-(1->2)-(α-L-rhamnopyranosyl)-(1->4)-(methyl α-D-galactopyranosid)uronate | 1012860-78-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: methyl (α-L-rhamnopyranosyl)-(1->4)-(methyl α-D-galactopyranosyluronate)-(1->2)-(α-L-rhamnopyranosyl)-(1->4)-(methyl α-D-galactopyranosid)uronate
• 英文别名: methyl (2S,3R,4R,5R,6S)-3-[(2S,3R,4R,5R,6S)-3-[(2S,3R,4R,5R,6S)-3,4-dihydroxy-6-methoxycarbonyl-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-4,5-dihydroxy-6-methyloxan-2-yl]oxy-4,5-dihydroxy-6-methoxyoxane-2-carboxylate
• CAS: 1012860-78-4
• 化学式: C₂₇H₄₄O₂₁
• 分子量: 704.634
• InChiKey: IKXNZGZSTBYMCF-AOOXKICASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -5.8
• 重原子数：
  48
• 可旋转键数：
  11
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  309
• 氢给体数：
  9
• 氢受体数：
  21

反应信息

• 作为反应物：
  描述：

  methyl (α-L-rhamnopyranosyl)-(1->4)-(methyl α-D-galactopyranosyluronate)-(1->2)-(α-L-rhamnopyranosyl)-(1->4)-(methyl α-D-galactopyranosid)uronate 在 sodium hydroxide 作用下， 以 水 为溶剂， 以77%的产率得到methyl α-L-rhamnopyranosyl-(1->4)-α-D-galactopyranosyluronate-(1->2)-α-L-rhamnopyranosyl-(1->4)-(α-D-galactopyranosid)uronate
  参考文献：
  名称：

  Synthesis of two repeat units corresponding to the backbone of the pectic polysaccharide rhamnogalacturonan I

  摘要：

  A tetrasaccharide corresponding to a sequence of the rhamnogalacturonan I backbone has been synthesized. This synthesis relies on only two protected monosaccharides and proceeds through a common disaccharide intermediate. Synthesis of this tetrasaccharide has been designed to allow for the addition of branching elements at the 4-positions of the rhamnosyl units, or further chain elongation at the 2-position. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carres.2007.10.030
• 作为产物：
  描述：

  在 palladium diacetate 氢气 作用下， 以 甲醇 、 溶剂黄146 、 乙酸乙酯 为溶剂， 反应 1.0h， 生成 methyl (α-L-rhamnopyranosyl)-(1->4)-(methyl α-D-galactopyranosyluronate)-(1->2)-(α-L-rhamnopyranosyl)-(1->4)-(methyl α-D-galactopyranosid)uronate
  参考文献：
  名称：

  Synthesis of two repeat units corresponding to the backbone of the pectic polysaccharide rhamnogalacturonan I

  摘要：

  A tetrasaccharide corresponding to a sequence of the rhamnogalacturonan I backbone has been synthesized. This synthesis relies on only two protected monosaccharides and proceeds through a common disaccharide intermediate. Synthesis of this tetrasaccharide has been designed to allow for the addition of branching elements at the 4-positions of the rhamnosyl units, or further chain elongation at the 2-position. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carres.2007.10.030