8-[(2-pyridylmethoxy)methyl]quinoline | 1196073-64-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 8-[(2-pyridylmethoxy)methyl]quinoline
• 英文别名: 8-(Pyridin-2-ylmethoxymethyl)quinoline
• CAS: 1196073-64-9
• 化学式: C₁₆H₁₄N₂O
• 分子量: 250.3
• InChiKey: PUUOWUZITDGAGW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  19
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  35
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  tris(triphenylphosphine)ruthenium(II) chloride 、 8-[(2-pyridylmethoxy)methyl]quinoline 以 甲醇 为溶剂， 以60%的产率得到(8-[(2-pyridylmethoxy)methyl]quinoline)RuCl2(triphenylphosphine)
  参考文献：
  名称：

  Preparation, characterization, and catalytic properties of (triphenylphosphine)ruthenium complexes bearing N,O,N′-tridentate ligands

  摘要：

  Preparation and characterization of (triphenylphosphine)ruthenium complexes bearing N,O,N'-tridentate ligands, [(L-1)RuCl(PPh3)(2)](BF4) (L-1 = 2-[(2-pyridylmethoxy)methyl] pyridine), 1), [(L-2)RuCl(PPh3)(2)](BF4) (L-2 = 8-(2-pyridylmethoxy)quinoline, 2) and [(L-3)RuCl2(PPh3)] (L-3 = 2-[(2-pyridylmethoxy)methyl] quinoline, 3) are described. Complexes 1-3 have been characterized by NMR and elemental analyses. Molecular structures of 2 and 3 have been determined by X-ray crystallography. Both compounds exhibit the octahedral geometry. L-2 adopts the facial configuration in 2 while L-3 is in a mer-arrangement in 3. Complexes 1-3 have proven to be able to catalyze the transfer hydrogenation of several ketones to alcohols in the presence of KOH and 2-propanol at refluxing, among which complex 3 was found to be the most active. (C) 2009 Elsevier B. V. All rights reserved.

  DOI：

  10.1016/j.ica.2009.06.055

文献信息

• Synthesis, structures and ethylene polymerization activity of chromium(III) complexes with N,O,N′-tridentate ligands
  作者：Fei Chen、Xiang-Yong Lu、Xue-Tai Chen、Hua-Yi Li、You-Liang Hu

  DOI：10.1016/j.ica.2012.02.037

  日期：2012.5

  This paper reports the synthesis and characterization of four neutral chromium(III) complexes bearing N,O,N'-tridentate ligands, [LCrCl3], (L = 2-[(2-pyridylmethoxy)methyl]pyridine, 1; L = 8-(2-pyridylmethoxy) quinoline, 2; L = 8-[(2-pyridylmethoxy)methyl]quinoline, 3; L = 8-(quinolin-8-ylmethoxy)quinoline,4). Molecular structures of 1-3 have been determined by X-ray crystallography, which show that L-1 and L-3 exhibit facial configuration in 1 and 3 while L-2 adopts meridional arrangement in 2. The ethylene polymerization experiments show that complexes 1-4 are moderately active precatalysts for ethylene polymerization with activation with MAO. (C) 2012 Elsevier B.V. All rights reserved.