2,6-Dihydroxy-8-isopropyl-7-methoxy-1,1-dimethyl-1,2-dihydro-dibenzo[a,d]cyclohepten-10-one

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 2,6-Dihydroxy-8-isopropyl-7-methoxy-1,1-dimethyl-1,2-dihydro-dibenzo[a,d]cyclohepten-10-one
• 英文别名: 4,13-Dihydroxy-5-methoxy-12,12-dimethyl-6-propan-2-yltricyclo[9.4.0.03,8]pentadeca-1,3,5,7,10,14-hexaen-9-one；4,13-dihydroxy-5-methoxy-12,12-dimethyl-6-propan-2-yltricyclo[9.4.0.03,8]pentadeca-1,3,5,7,10,14-hexaen-9-one
• 化学式: C₂₁H₂₄O₄
• 分子量: 340.419
• InChiKey: XOGZLEYOOYFYAS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  25
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  66.8
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  美丽红豆杉素-A 在 sodium tetrahydroborate 、 cerium(III) chloride 作用下， 以 乙醇 为溶剂， 反应 10.0h， 以10%的产率得到6,10-Dihydroxy-8-isopropyl-7-methoxy-1,1-dimethyl-1,10-dihydro-dibenzo[a,d]cyclohepten-2-one
  参考文献：
  名称：

  Diterpenes from Taxus mairei

  摘要：

  Eleven new diterpenes including one isopimarane, five abietanes and five 9(10-->20)abeo-abietanes were isolated from the twigs of Taxus mairei. Their structures were determined by chemical and spectroscopic methods. (C) 1998 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0031-9422(98)00443-9

文献信息

• Diterpenes from Taxus mairei
  作者：Shung-Jim Yang、Jim-Min Fang、Yu-Shia Cheng

  DOI：10.1016/s0031-9422(98)00443-9

  日期：1998.12

  Eleven new diterpenes including one isopimarane, five abietanes and five 9(10-->20)abeo-abietanes were isolated from the twigs of Taxus mairei. Their structures were determined by chemical and spectroscopic methods. (C) 1998 Elsevier Science Ltd. All rights reserved.