1,2-bis(quinolin-2-yl)diazene

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 1,2-bis(quinolin-2-yl)diazene
• 英文别名: Azoquinoline；di(quinolin-2-yl)diazene
• 化学式: C₁₈H₁₂N₄
• 分子量: 284.32
• InChiKey: ZAFQJJHRAORSEQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  22
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  50.5
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  N,N'-di-[2]quinolyl-hydrazine 在 三氯化铁 作用下， 以 水 、 丙酮 为溶剂， 以81%的产率得到1,2-bis(quinolin-2-yl)diazene
  参考文献：
  名称：

  A Convenient Method for Dehydrogenation of Symmetric Hydrazo Compounds

  摘要：

  A convenient method using FeCl3 as oxidant to dehydrogenate symmetric hydrate compounds is reported for the first time. The method is superior to other known methods for dehydrogenating ArNHNHAr. It needs only cheap and less toxic reagents, mild conditions and short reaction time. Eight symmetric ate compounds are prepared in good yields.

  DOI：

  10.1080/00397919908085972

文献信息

• Regioselective halogenation of pyridinium N-(benzoazynyl) aminides as a way to produce N-benzyl-α-aminobenzoazines
  作者：Elena Gala、M. Luisa Izquierdo、Julio Alvarez-Builla

  DOI：10.1016/j.tet.2018.03.064

  日期：2018.5

  N-(benzoazynyl) aminides with N-halosuccinimides provides a mild and regioselective method to functionalize the negatively charged diazine moiety in most cases. In some examples, however, formation of other products is explained. Finally, alkylation of the exocyclic nitrogen and reduction of the N–N bond provides a simple and straightforward strategy to obtain functionalized N-benzyl-benzoazynyl-α-amines.

  在大多数情况下，用N-卤代琥珀酰亚胺卤化吡啶鎓N-（苯并炔基）氨基化物提供了温和的区域选择性方法，以使带负电的二嗪部分官能化。但是，在某些示例中，将解释其他产品的形成。最后，环外氮的烷基化和N–N键的还原为获得官能化的N-苄基-苯并炔基-α-胺提供了一种简单明了的策略。
• A Convenient Method for Dehydrogenation of Symmetric Hydrazo Compounds
  作者：Cai-Lan Wang、Xiao-Xia Wang、Xiao-Yang Wang、Jun-Ping Xiao、Yu-Lu Wang

  DOI：10.1080/00397919908085972

  日期：1999.10

  A convenient method using FeCl3 as oxidant to dehydrogenate symmetric hydrate compounds is reported for the first time. The method is superior to other known methods for dehydrogenating ArNHNHAr. It needs only cheap and less toxic reagents, mild conditions and short reaction time. Eight symmetric ate compounds are prepared in good yields.