(2S,3R)-2-methyl-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3-dihydropyran-6-one | 54835-71-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2S,3R)-2-methyl-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3-dihydropyran-6-one
• CAS: 54835-71-1
• 化学式: C₁₂H₁₈O₈
• 分子量: 290.27
• InChiKey: KZOPXYPPFZYEHT-RKPZXMFYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.6
• 重原子数：
  20
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  126
• 氢给体数：
  4
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  (2S,3R)-2-methyl-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3-dihydropyran-6-one 、 乙酸酐 、 吡啶 生成 [(2R,3S,4S,5R,6R)-3,4,5-triacetyloxy-6-[[(2S,3R)-2-methyl-6-oxo-2,3-dihydropyran-3-yl]oxy]oxan-2-yl]methyl acetate
  参考文献：
  名称：

  NUMATA, ATSUSHI;TAKAHASHI, CHIKA;FUJIKI, RYOKO;KITANO, EISAKU;KITAJIMA, A+, CHEM. AND PHARM. BULL., 38,(1990) N0, C. 2862-2865

  摘要：

  DOI：

文献信息

• NUMATA, ATSUSHI;TAKAHASHI, CHIKA;FUJIKI, RYOKO;KITANO, EISAKU;KITAJIMA, A+, CHEM. AND PHARM. BULL., 38,(1990) N0, C. 2862-2865
  作者：NUMATA, ATSUSHI、TAKAHASHI, CHIKA、FUJIKI, RYOKO、KITANO, EISAKU、KITAJIMA, A+

  DOI：——

  日期：——
• METHODS OF DIAGNOSING DISEASE
  申请人：4D Pharma Cork Limited

  公开号：EP3947743A1

  公开（公告）日：2022-02-09
• COMPOSITION COMPRISING OSMUNDACETONE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF FOR PREVENTING OR TREATING BONE DISEASE
  申请人：KORPHARM CO., LTD.

  公开号：US20200129450A1

  公开（公告）日：2020-04-30

  The present invention relates to a composition comprising osmundacetone or a pharmaceutically acceptable salt thereof for preventing or treating bone diseases. More specifically, the present invention relates to: a composition comprising osmundacetone, a pharmaceutically acceptable salt thereof, or an Osmunda japonica extract as an effective ingredient, for preventing or treating osteoporosis, rheumatoid arthritis, arthralgia, Paget disease, bone metastatic cancer, or fracture; a food composition for improvement; a use of a salt; and a treatment method. The composition according to the present invention shows a strong inhibitory activity against proliferation and differentiation of osteoclast which causes bone loss, and activation of differentiation of osteoblast, and thus can be usefully utilized in developing medicines for safe and effective treatment of bone diseases or functional foods for improving symptoms of bone diseases
• [EN] METHODS OF DIAGNOSING DISEASE<br/>[FR] PROCÉDÉS DE DIAGNOSTIC D'UNE MALADIE
  申请人：4D PHARMA CORK LTD

  公开号：WO2020201457A1

  公开（公告）日：2020-10-08

  The application provides new and improved methods for diagnosing IBS.