4-Vinyloxy-acetophenon | 1849-92-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 4-Vinyloxy-acetophenon
• 英文别名: p-(Vinyloxy)-acetophenon；p-Acetyl-phenoxy-aethylen；1-[4-(Ethenyloxy)phenyl]ethan-1-one；1-(4-ethenoxyphenyl)ethanone
• CAS: 1849-92-9
• 化学式: C₁₀H₁₀O₂
• 分子量: 162.188
• InChiKey: QFQKJEXAGQXTHR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  4-Vinyloxy-acetophenon 在 过氧化氢苯甲酰 作用下， 以 氯仿 为溶剂， 反应 2.0h， 以25%的产率得到4-acetylphenoxyoxirane
  参考文献：
  名称：

  Sone, Tomomichi; Isobe, Masakazu; Takabatake, Eigo, Chemical and pharmaceutical bulletin, 1989, vol. 37, # 7, p. 1922 - 1924

  摘要：

  DOI：

文献信息

• Novel silane compounds carrying a hydrazone or diazo functional group in order to functionalize solid supports and immobilize biological molecules on these supports
  申请人：Martin Franck

  公开号：US20090208374A1

  公开（公告）日：2009-08-20

  The invention relates to novel silane compounds corresponding to the following formula (I): in which R 1 can represent a methyl group, R 2 and R 3 can represent a hydrogen atom, A can represent —O—, E can represent an alkylene group, X can represent a methoxysilane group, Z can represent a simple bond and Y can represent an —N 2 or —N—NH 2 group. Use of these silane compounds to functionalize solid supports and to immobilize biological molecules on these supports.

  该发明涉及与以下式（I）相对应的新型硅烷化合物： 其中R1可以代表一个甲基基团，R2和R3可以代表一个氢原子，A可以代表—O—，E可以代表一个烷基基团，X可以代表一个甲氧硅烷基团，Z可以代表一个简单键，Y可以代表一个—N2或—N—NH2基团。利用这些硅烷化合物对固体支持物进行功能化，并将生物分子固定在这些支持物上。
• Uv-crosslinkable copolymers
  申请人：Meyer Harald

  公开号：US20050080213A1

  公开（公告）日：2005-04-14

  The present invention relates to the use of acetophenone or benzophenone derivatives of the formula I where R is unsubstituted or substituted C 1 to C 3 alkyl, C 6 to C 10 aryl or aralkyl having from 6 to 10 carbon atoms in the aryl moiety and from 1 to 6 carbon atoms in the alkyl moiety as copolymerizable photoinitiators. The invention further relates to copolymers containing acetophenone or benzophenone derivatives of the formula I in copolymerized form, to processes for preparing said copolymers, and to the use of said copolymers in UV crosslinkable compositions.

  本发明涉及使用公式I中的苯乙酮或苯基苯酮衍生物，其中R为未取代或取代的C1到C3烷基，C6到C10芳基或含有6到10个碳原子的芳基烷基，以及含有1到6个碳原子的烷基，作为共聚光引发剂。本发明还涉及含有公式I中的苯乙酮或苯基苯酮衍生物的共聚物，用于紫外线交联的组合物的制备过程以及使用该共聚物在紫外线交联组合物中的应用。
• Cyclic Amine Compound and Use Thereof for the Prophylaxis or Treatment of Hypertension
  申请人：Kuroita Takanobu

  公开号：US20100121048A1

  公开（公告）日：2010-05-13

  The present invention relates to a compound represented by the formula: (I) wherein ring A is a 5- or 6-membered aromatic heterocycle optionally having substituent (s); U, V and W are each independently C or N, provided that when any one of U, V and W is N, then the others should be C; Ra and Rb are each independently a cyclic group optionally having substituent(s), a C 1-10 alkyl group optionally having substituent(s), a C 2-10 alkenyl group optionally having substituent(s), or a C 2-10 alkynyl group optionally having substituent(s); X is a bond, or a spacer having 1 to 6 atoms in the main chain; Y is a spacer having 1 to 6 atoms in the main chain; Rc is a hydrocarbon group optionally containing heteroatom(s) as the constituting atom(s), which optionally has substituent(s); m and n are each independently 1 or 2; and ring B optionally further has substituent(s), or a salt thereof. The compound of the present invention has excellent renin inhibitory activity, and thus is useful as an agent for the prophylaxis or treatment of hypertension, various organ damages attributable to hypertension, and the like.

  本发明涉及一种由式(I)表示的化合物：其中，环A是一种5或6成员的芳香杂环，可选地具有取代基；U、V和W分别独立地为C或N，但当U、V和W中的任何一个为N时，其他的应为C；Ra和Rb分别独立地为一个环状基团，可选地具有取代基；一个C1-10烷基，可选地具有取代基；一个C2-10烯基，可选地具有取代基；或一个C2-10炔基，可选地具有取代基；X是一条键或具有1到6个原子的主链间隔；Y是具有1到6个原子的主链间隔；Rc是一个含有杂原子作为构成原子的碳氢基团，可选地具有取代基；m和n分别独立地为1或2；环B可选地具有取代基，或其盐。本发明的化合物具有优异的肾素抑制活性，因此可用作预防或治疗高血压、高血压引起的各种器官损伤等的药物。
• Thiol compound derivative, hardening compositions containing these derivatives and molded articles thereof
  申请人：——

  公开号：US20040162368A1

  公开（公告）日：2004-08-19

  The present invention relates to a thiol compound derivative represented by the following formula (1), a curable composition containing the derivative, and a molded product made of the composition. More particularly, the invention relates to a thiol compound derivative which is added to a polymer having reactivity to a thiol derivative substituent to provide a curable composition, a curable composition containing the derivative and a crosslinkable halogen-containing crosslinking polymer, and a crosslinked molded product of the composition. 1 wherein X 1 , X 2 and X 3 are each a group represented by the following formula (2). 2

  本发明涉及由下式（1）表示的硫醇化合物衍生物、含有该衍生物的可固化组合物以及由该组合物制成的模塑产品。更具体地说，本发明涉及一种硫醇化合物衍生物，将其添加到对硫醇衍生物取代基具有反应活性的聚合物中，以提供一种可固化组合物、一种含有该衍生物和一种可交联含卤交联聚合物的可固化组合物，以及一种由该组合物制成的交联模塑产品。 1 其中 X 1 , X 2 和 X 3 分别是下式（2）所代表的一个基团。 2
• FeCl₃/ZnI₂-Catalyzed Synthesis of Benzo[<i>d</i>]imidazo[2,1-<i>b</i>]thiazole through Aerobic Oxidative Cyclization between 2-Aminobenzothiazole and Ketone
  作者：Subhajit Mishra、Kamarul Monir、Shubhanjan Mitra、Alakananda Hajra

  DOI：10.1021/ol5028893

  日期：2014.12.5

  The FeCl3/ZnI2-catalyzed aerobic oxidative cyclization between 2-aminobenzothiazole and ketone/chalcone for the synthesis of benzo[d]imidazo[2,1-b]thiazole is described. A variety of fused benzoimidazothiazole derivatives are obtained by this protocol.