2,3,6,7-tetrahydro-1H,5H-benzoquinolizin-1-ol | 101359-27-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 2,3,6,7-tetrahydro-1H,5H-benzoquinolizin-1-ol
• 英文别名: 1-Azatricyclo[7.3.1.05,13]trideca-5,7,9(13)-trien-3-ol
• CAS: 101359-27-7
• 化学式: C₁₂H₁₅NO
• 分子量: 189.257
• InChiKey: CXOVGXHHPLWNEC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  14
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  23.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2,3,6,7-tetrahydro-1H,5H-benzoquinolizin-1-ol 在 phosphorus pentoxide 作用下， 生成 久洛尼定
  参考文献：
  名称：

  Silhankova, Alexandra; Trska, Petr; Vlkova, Daniela, Collection of Czechoslovak Chemical Communications, 1985, vol. 50, # 5, p. 1048 - 1056

  摘要：

  DOI：
• 作为产物：
  描述：

  1-(3-氯-2-羟基丙基)-1,2,3,4-四氢喹啉 生成 2,3,6,7-tetrahydro-1H,5H-benzoquinolizin-1-ol
  参考文献：
  名称：

  SILHANKOVA, A.;TRSKA, P.;VLKOVA, D.;FERLES, M., COLLECT. CZECHOSL. CHEM. COMMUN., 1985, 50, N 5, 1048-1056

  摘要：

  DOI：

文献信息

• [EN] FLUORESCENT RED EMITTING FUNCTIONALIZABLE PH PROBES<br/>[FR] SONDES À PH FONCTIONNALISABLES ÉMETTANT DANS LE ROUGE FLUORESCENT
  申请人：PARIS SCIENCES LETTRES QUARTIER LATIN

  公开号：WO2015097262A1

  公开（公告）日：2015-07-02

  The present invention relates to pH probes of formula I: wherein: W represents O, NH, N(alkyl), Si(alkyl)2, CH2, CH(alkyl), C(alkyl)2; preferably W represents O; X1 and X1' represent both H, both Me or both -CH2-S03H; X2 and X2' represent both H or both Me; X3 and X 3' represent both H or both Me; X4 and X 4' represent both H or both Me; X5 and X5' represent both H or both Me; X6 and X6' represent both H or both Me; Z1, Z2 and Z3, represent each independently H, electron withdrawing group or electron donating group, L represents a single bound or a linker, Y represents a reactive group, or a bioactive group. The invention also relates to a process for manufacturing said compounds. The invention further relates to the use of the compounds of the invention as pH probes.