cis-3,4-Dimethyl-cis,cis-cycloocta-1,5-diene | 40391-80-8

• 分子结构分类: 有机化合物 - 碳氢化合物 - 不饱和烃
• 英文名称: cis-3,4-Dimethyl-cis,cis-cycloocta-1,5-diene
• 英文别名: cis-3,4-Dimethyl-cyclooctadien-1,5；3r,4c-dimethyl-cycloocta-1c,5c-diene；3r,4c-Dimethyl-cycloocta-1c,5c-dien；(1Z,3S,4R,5Z)-3,4-dimethylcycloocta-1,5-diene
• CAS: 40391-80-8
• 化学式: C₁₀H₁₆
• 分子量: 136.237
• InChiKey: SAOXWIPRWNIEIH-PUGGOQMBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  反-1,3-戊二烯 在 对苯二酚 作用下， 生成 cis-3,4-Dimethyl-cis,cis-cycloocta-1,5-diene
  参考文献：
  名称：

  Car-driving abilities of people with tetraplegia

  摘要：

  Objectives: To examine the relationship between the spinal cord injury (SCI) level, age,, and car-driving ability in people with tetraplegia and to explore the association between car-driving ability and social activity.Design: Retrospective clinical survey.Setting: Rehabilitation center in Japan.Patients: Sixty-two subjects with traumatic complete tetraplegia.Interventions: Driving evaluation; comprehensive driver's training (muscle strengthening, transfer training, adjustment of equipment, on-road training); and questionnaire (car-driving status, employment, participation in sports).Main Outcome Measures: The SCI level (Zancolli's classification), age, functional status of activities of daily living (ADLs), and driving ability were obtained from the medical records. Vocational status and engagement in sports activities were investigated by questionnaire.Results: The SCI level and age strongly influenced the patients' ability to drive a car independently. The highest neurologic level in which independent driving was achievable was C6A. Toilet transfer ability almost paralleled the ability to drive a car. Eighty-four percent of the people with tetraplegia who had a defined job could drive independently and 70% of the driving-independent individuals held a job. Half of driving-independent individuals participated in some sports activities.Conclusions: Toilet transfer ability is a reliable indicator for driver's training. Driving ability is an important factor that allows individuals with tetraplegia to participate in work and sports-related activities.

  DOI：

  10.1053/apmr.2001.26089

文献信息

• Formation and thermal rearrangements of some dimers of butadiene and piperylene. Tests of the validity of thermochemical-kinetic arguments for identification of common biradical intermediates
  作者：Jerome A. Berson、Peter B. Dervan、Roger Malherbe、Jerry A. Jenkins

  DOI：10.1021/ja00435a031

  日期：1976.9

  dimerization of butadiene and piperylene and the thermal rearrangements of the corresponding dimers are investigated by kinetic and stereochemical techniques. Particular attention is given to the question whether, in the Diets-Alder dimerization of the dienes la or lb, intermediates are involved that are common to the 1,3-sigmatropic rearrangements of the corresponding (2 + 2] dimers 3a and 3b. Substituents

  通过动力学和立体化学技术研究了丁二烯和戊间二烯二聚的机理以及相应二聚体的热重排。特别注意以下问题：在二烯 1a 或 lb 的 Diets-Alder 二聚化中，是否涉及相应的 (2 + 2] 二聚体 3a 和 3b 的 1,3-σ 重排所共有的中间体。在 cis-1,2-divinylcyelobutane (Sa) 的末端乙烯基位置阻止正常的立体定向船状 Cope 重排为 3,4-二甲基-顺,cis-cycloocta-1,5-diene 并允许检测新的“非船”过程，whicp 导致立体异构体 pr6duct。船状速率常数随着 Sa > cTT-8 > cCT-8 > cCC-8 系列中末端顺式甲基取代基的增加而下降。效应的总范围等于 1.81 XI 05。反式-1,2-二丙烯基环丁烷也产生 Cope 重排产物，但该反应仅通过间接机制发生：先差向异构化为顺式异构体，然后 Cope 重排后者。反式-3